Y
Yuan Ruan
Researcher at California Institute of Technology
Publications - 2
Citations - 484
Yuan Ruan is an academic researcher from California Institute of Technology. The author has contributed to research in topics: Multicellular organism & Single-cell analysis. The author has an hindex of 2, co-authored 2 publications receiving 319 citations.
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Journal ArticleDOI
Observing the cell in its native state: Imaging subcellular dynamics in multicellular organisms
Tsung-Li Liu,Srigokul Upadhyayula,Daniel E. Milkie,Ved P. Singh,Kai Wang,Ian A. Swinburne,Kishore R. Mosaliganti,Zach M. Collins,Tom W. Hiscock,Jamien Shea,Abraham Q. Kohrman,Taylor N Medwig,Daphné Dambournet,Ryan Forster,Brian Cunniff,Brian Cunniff,Yuan Ruan,Hanako Yashiro,Steffen Scholpp,Steffen Scholpp,Elliot M. Meyerowitz,Dirk Hockemeyer,David G. Drubin,Benjamin L. Martin,David Q. Matus,Minoru Koyama,Sean G. Megason,Tom Kirchhausen,Eric Betzig +28 more
TL;DR: AO-LLSM takes high-resolution live-cell imaging of subcellular processes from the confines of the coverslip to the more physiologically relevant 3D environment within whole transparent organisms and creates new opportunities to study the phenotypic diversity of intracellular dynamics, extracellular communication, and collective cell behavior across different cell types, organisms, and developmental stages.
Posted ContentDOI
Observing the Cell in Its Native State: Imaging Subcellular Dynamics in Multicellular Organisms
Tsung-Li Liu,Srigokul Upadhyayula,Daniel E. Milkie,Ved P. Singh,Kai Wang,Ian A. Swinburne,Kishore R. Mosaliganti,Zach M. Collins,Tom W. Hiscock,Jamien Shea,Abraham Q. Kohrman,Taylor N Medwig,Daphné Dambournet,Ryan Forster,Brian Cunniff,Yuan Ruan,Hanako Yashiro,Steffen Scholpp,Elliot M. Meyerowitz,Dirk Hockemeyer,David G. Drubin,Benjamin L. Martin,David Q. Matus,Minoru Koyama,Sean G. Megason,Tom Kirchhausen,Eric Betzig +26 more
TL;DR: Combining lattice light sheet microscopy with adaptive optics enables high speed, high resolution in vivo 3D imaging of dynamic processes inside cells under physiological conditions within their parent organisms.