Yuan Soon Ho

TL;DR: Results suggest that SP1 plays a critical role in the p27/Kip1 gene transcriptional activation that may be subsequently involved in the TB-induced A431 cancer cell differentiation process.

TL;DR: In this paper, the authors provide polyclonal anti-α-enolase I antibodies and monoclonal single-chain variable fragment (scFv) anti-β-enolate antibodies for diagnosis and treatment of cancers, autoimmune disorders, ischemia and bacterial infection.

TL;DR: Logistic regression analysis showed that individuals with the MSH2 rs2303425 C/C genotype had a significantly increased risk of breast cancer compared to those with the T/T genotype, particularly in early-onset breast cancer patients with the luminal A subtype.

TL;DR: The results revealed that the apoptotic effect induced by TB in the HL60 cell was not through the general differentiation mechanisms evidenced by evaluation of three recognized markers, including CD11b, CD33, and morphological features, and implied that additional mediators other than mitochondria membrane permeability might contribute to the TB-induced cellular apoptosis signaling.

TL;DR: Evidence is provided that glutathione S-transferase mu 3 may play an important role in preventing breast cancer treatment-induced cellular cytotoxicity and in suppressing tumourigenic ability of MCF-7 cells and increase tumour cell apoptosis.