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Yuan Soon Ho

Researcher at Taipei Medical University

Publications -  160
Citations -  7212

Yuan Soon Ho is an academic researcher from Taipei Medical University. The author has contributed to research in topics: Apoptosis & Cancer cell. The author has an hindex of 42, co-authored 155 publications receiving 6411 citations. Previous affiliations of Yuan Soon Ho include National Taiwan University & Taipei Medical University Hospital.

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Journal ArticleDOI

Signaling mechanism of thrombin-induced gingival fibroblast-populated collagen gel contraction.

Jiiang-Huei Jeng, +9 more
- 01 Jan 2006 - 
TL;DR: Results indicate that thrombin is crucial in the periodontal inflammation and wound healing by promoting GF contraction, mainly mediated via PAR‐1 activation, PLC activation, extracellular calcium influx via L‐type calcium channel, and the calcium/CaM–MLCK and Rho kinase activation pathway.
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Induction of bax protein and degradation of lamin A during p53-dependent apoptosis induced by chemotherapeutic agents in human cancer cell lines

Yuan Soon Ho, +3 more
- 15 Jan 1999 - 
TL;DR: It was found that lamin A and poly-(ADP ribose) polymerase (PARP) protein degradation coincided when the Bax protein level was elevated in the nuclear membrane of cells affected by drug stimuli, and inhibition of Bax expression could specifically block lamination A but not PARP cleavage in apoptotic cancer cells.
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Protease-activated receptor-1-induced calcium signaling in gingival fibroblasts is mediated by sarcoplasmic reticulum calcium release and extracellular calcium influx

Jiiang-Huei Jeng, +10 more
- 01 Jun 2004 - 
TL;DR: Results indicate that mitochondrial calcium efflux and calcium-calmodulin pathways are related to thrombin and PAR-1 induced [Ca2+]i in GF.
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The in vivo antitumor effects on human COLO 205 cancer cells of the 4,7-dimethoxy-5-(2-propen-1-yl)-1,3-benzodioxole (apiole) derivative of 5-substituted 4,7-dimethoxy-5-methyl-l,3-benzodioxole (SY-1) isolated from the fruiting body of Antrodia camphorate

Po Li Wei, +10 more
- 01 Oct 2012 - 
TL;DR: Apiole markedly decreased the growth of COLO 205 human colon cancer cell tumor xenografts in an athymic nude mouse model system through the up-regulation of cell cycle regulators, such as p53, p21/Cip1, and p27/Kip1.
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Advanced glycosylation end products induce nitric oxide synthase expression in C6 glioma cells: involvement of a p38 MAP kinase-dependent mechanism.

Chien-Huang Lin, +5 more
- 12 Oct 2001 - 
TL;DR: In this paper, the role of the p38 MAPK signaling pathway in advanced glycosylation end products (AGEs)-induced iNOS expression in C6 glioma cells was investigated.