Y
Yuan Soon Ho
Researcher at Taipei Medical University
Publications - 160
Citations - 7212
Yuan Soon Ho is an academic researcher from Taipei Medical University. The author has contributed to research in topics: Apoptosis & Cancer cell. The author has an hindex of 42, co-authored 155 publications receiving 6411 citations. Previous affiliations of Yuan Soon Ho include National Taiwan University & Taipei Medical University Hospital.
Papers
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Journal ArticleDOI
Small G protein signalling modulator 2 (SGSM2) is involved in oestrogen receptor-positive breast cancer metastasis through enhancement of migratory cell adhesion via interaction with E-cadherin.
Juo Han Lin,Wen Jui Lee,Han-Chung Wu,Chih Hsiung Wu,Li Ching Chen,Chi-Cheng Huang,Hang Lung Chang,Tzu Chun Cheng,Hui Wen Chang,Chi-Tang Ho,Shih Hsin Tu,Yuan Soon Ho +11 more
TL;DR: The findings demonstrated that SGSM2 is a plasma membrane protein that strongly interacted with E-cadherin/β-catenin that plays a role in modulating cell adhesion and cytoskeleton dynamics during cancer migration.
Patent
Use of outer membrane protein a (ompa) in treatment/prevention/diagnosis of infections caused by klebsiella pneumoniae and other gram-negative bacteria
Yi Yuan Yang,Hsueh-Hsia Wu,Sy Jye Leu,Neng-Yao Shih,I-Jen Huang,Ching-Yu Lin,Wen-Shyang Hsieh,Ko-Jiunn Liu,Shih-Yi Huang,Yueh Lun Lee,Chi Hsin Lee,Yuan Soon Ho,Shih-Lan Hsu +12 more
TL;DR: In this paper, a method for the treatment and prevention of bacterial infection caused by klebsiella pneumoniae and other gram-negative bacteria in central nervous system and/or peripheral blood circulation in a mammal by administering effective amount of outer membrane protein A (OmpA) or its derivatives to a mammal.
Journal ArticleDOI
Chloroquine Potentiates the Anticancer Effect of Pterostilbene on Pancreatic Cancer by Inhibiting Autophagy and Downregulating the RAGE/STAT3 Pathway.
Rong Jane Chen,Yi-Jhen Lyu,Yu Ying Chen,Yen-Chien Lee,Min-Hsiung Pan,Yuan Soon Ho,Ying Jan Wang,Ying Jan Wang,Ying Jan Wang +8 more
TL;DR: In this article, the authors investigated whether the autophagy inhibitor chloroquine could potentiate the anticancer effect of pterostilbene in the PDAC cell lines MIA PaCa-2 and BxPC-3, as well as in an orthotopic animal model.
Journal ArticleDOI
Long-term ethanol exposure causes human liver cancer cells to become resistant to mitomycin C treatment through the inactivation of bad-mediated apoptosis.
Ching Shui Huang,Yi Ru Lee,Ching Shyang Chen,Shih Hsin Tu,Ying Jan Wang,Chia Hwa Lee,Li Ching Chen,Hui Wen Chang,Chien Hsi Chang,Su Chih-Ming,Chih Hsiung Wu,Yuan Soon Ho,Yuan Soon Ho +12 more
TL;DR: In vivo and in vitro studies demonstrated that AKT‐ and extracellular signal‐regulated kinase (ERK)‐mediated survival factors inhibited the Bad‐induced mitochondrial apoptotic signals that were involved in E40 tumor cells and that conferred resistance to MMC.
Journal ArticleDOI
A novel anti-tumor/anti-tumor-associated fibroblast/anti-mPEG tri-specific antibody to maximize the efficacy of mPEGylated nanomedicines against fibroblast-rich solid tumor.
Michael Chen,Ming Thau Sheu,Tian-Lu Cheng,Steve R. Roffler,Shyr-Yi Lin,Shyr-Yi Lin,Chen Yi-Jou,Yi-An Cheng,Jing Jy Cheng,Jing Jy Cheng,Hsin-Yu Chang,Tung-Yun Wu,An-Pei Kao,Yuan Soon Ho,Yuan Soon Ho,Kuo-Hsiang Chuang +15 more
TL;DR: In this article, an anti-HER2/anti-FAP/anti mPEG tri-specific antibody (TsAb) was developed for one-step conversion of methoxypolyethylene glycol (mPEG)-coated liposomal doxorubicin (Lipo-Dox) to immunoliposomes.