Z
Zihua Gong
Researcher at University of Texas MD Anderson Cancer Center
Publications - 6
Citations - 655
Zihua Gong is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Homologous recombination & Cajal body. The author has an hindex of 5, co-authored 6 publications receiving 379 citations. Previous affiliations of Zihua Gong include Cleveland Clinic Lerner Research Institute.
Papers
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Journal ArticleDOI
BAP1 links metabolic regulation of ferroptosis to tumour suppression.
Yilei Zhang,Jiejun Shi,Xiaoguang Liu,Li Feng,Zihua Gong,Zihua Gong,Pranavi Koppula,Pranavi Koppula,Kapil Sirohi,Xu Li,Xu Li,Yongkun Wei,Hyemin Lee,Li Zhuang,Gang Chen,Zhen Dong Xiao,Zhen Dong Xiao,Mien Chie Hung,Junjie Chen,Junjie Chen,Peng Huang,Peng Huang,Wei Li,Boyi Gan,Boyi Gan +24 more
TL;DR: It is shown that BAP1 suppresses SLC7A11 expression and cystine uptake, thereby promoting ferroptosis and inhibiting tumour growth and uncovering a previously unappreciated epigenetic mechanism coupling ferroPTosis to tumour suppression.
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PTIP associates with Artemis to dictate DNA repair pathway choice
Jiadong Wang,Asaithamby Aroumougame,Markus Löbrich,Yujing Li,David J. Chen,Junjie Chen,Zihua Gong +6 more
TL;DR: Artemis is the major downstream effector of the 53BP1 pathway, which prevents end resection and promotes nonhomologous end-joining and therefore directly competes with the homologous recombination repair pathway.
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Proteomic Analysis of the Human Cyclin-dependent Kinase Family Reveals a Novel CDK5 Complex Involved in Cell Growth and Migration
Shuangbing Xu,Xu Li,Zihua Gong,Wenqi Wang,Yujing Li,Binoj Nair,Hai-long Piao,Kunyu Yang,Gang Wu,Junjie Chen +9 more
TL;DR: In this paper, the authors conducted a proteomic analysis of the cyclin-dependent kinases (CDKs) and identified their associated protein complexes in two different cell lines using a modified SAINT (Significance Analysis of INTeractome) method.
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Proteomic Analysis Reveals a Novel Mutator S (MutS) Partner Involved in Mismatch Repair Pathway.
TL;DR: This study uncovers new components involved in the MMR pathway, which provides candidate genes that may be responsible for the development of MSI-positive cancers.
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Fam118B, a newly identified component of Cajal bodies, is required for Cajal body formation, snRNP biogenesis and cell viability.
Yujing Li,Ka Wing Fong,Mengfan Tang,Xin Han,Zihua Gong,Wenbin Ma,Michael D. Hebert,Zhou Songyang,Zhou Songyang,Junjie Chen +9 more
TL;DR: Data indicate that Fam118B, by regulating SmD1 symmetric dimethylarginine modification, plays an important role in Cajal body formation, snRNP biogenesis and cell viability.