American Pharmacists Association

About: American Pharmacists Association is a other organization based out in Washington D.C., District of Columbia, United States. It is known for research contribution in the topics: Pharmacist & Pharmacy. The organization has 2413 authors who have published 1969 publications receiving 30470 citations. The organization is also known as: APhA & American Pharmaceutical Association.

Opioid prescribing is a surrogate for inadequate pain management resources

Abstract: The registrar of the College of Physicians and Surgeons of Ontario stated in 2010 that “opioids are an important part of the modern arsenal for treating chronic non-cancer pain.”[1][1] He noted that clear guidance on the prescribing of opioids was needed and that the National Opioid Use

Synthesis and anti-inflammatory activities of new cyanopyrane derivatives fused with steroidal nuclei.

Abstract: Thirteen new heterocyclic derivatives containing a cyanopyrane ring fused to a steroidal moiety were conveniently synthesized and screened for their anti-inflammatory potencies comparable to that of the glucocorticoid prednisolone. Four compounds 5a, 5b, 6b, and 8 exhibited superior anti-inflammatory indices (in rats, protection against carrageenan induced edema and inhibition of plasma PGE). All the candidates were less toxic than the reference drug concerning LD(50) values. Synthetic steroidal structures fused to a substituted cyanopyrane ring seem to be a promising approach in search for novel leads for potent anti-inflammatory agents.

A study investigating the level of satisfaction with the health services provided by the Pharmacist at ENT hospital, Eastern Region Alahsah, Kingdom of Saudi Arabia.

Abstract: The current study aims to evaluate the patient’s level of satisfaction with health care services provided by the pharmacist at Aljaber ENT hospital, Eastern Region Alahsah, Kingdom of Saudi Arabia. A cross sectional study was planned from 1st March 2011 until 31st May 2011. A 27 item questionnaire was used, scoring of the responses was done to classify the patient satisfaction into sublevels. The maximum possible score was 36; those scoring less than twenty were graded as poor satisfaction level followed by moderate satisfaction level 21–25, good satisfaction level 26–30 and high satisfaction level 31–36. Statistical package for social science version 13® was used to analyze data, One-way ANOVA and independent sample t-test were applied to see the differences in the level of satisfaction. Every third patient visiting pharmacy was given a chance to participate in this study. A total of N = 991 patients were randomized using the pharmacy appointment number. Of whom 657 patients have shown willingness to participate in this study. The response rate of this study was 66.30%, most of the respondents 383 (58.1%) were male ranging from the age group of 21–40 years with a mean age of 32 years SD 9.73. The mean score for all patients was 26.15 SD ±3.4. Among all the demographic variables a significant difference in satisfaction level was found among in terms of age (df = 8, F = 8.36, p = <0.001∗), gender (t = −4.089, df = 656, p=<0.001∗) and race (df = 2, F = 8.47, p = <0.001. The satisfaction level among Saudi nationals was least in comparison to Egyptians and others. In general, it is seen that respondents of age 56–60 years were most satisfied with the healthcare services provided by the pharmacist. In addition, the satisfaction level was higher among female patients in comparison to men.

Comparison of visual and turbidimetric methods for determining short-term compatibility of intravenous critical-care drugs.

Abstract: Visual and turbidimetric methods for determining the short-term compatibility of critical-care i.v. drugs were compared. In phase 1, serial dilutions of calcium chloride and magnesium sulfate were examined visually and turbidimetrically to test the sensitivity of the spectrophotometric method used. In phase 2, i.v. solutions of dobutamine, dopamine, lidocaine, nitroglycerin, and nitroprusside were prepared and studied in all possible combinations of two, three, four and five drugs, for a total of 26 different combinations. In phase 3, 45 two-drug combinations previously reported as physically incompatible were studied. Visual inspection was conducted against a dark and a light background; changes were graded as slight, moderate, or gross. Absorbance was determined at 650 nm; an absorbance value of greater than 0.010 was considered to be evidence of turbidity. Visual, turbidimetric, and pH measurements were done at zero, one, and three hours after mixing. Samples of the calcium chloride-magnesium sulfate mixture that were graded visually as having a slight precipitate had absorbance readings less than 0.010. No physical evidence of incompatibility was observed by either method for dobutamine, dopamine, lidocaine, nitroglycerin, and nitroprusside in any combination. In phase 3, 19 drug combinations were shown to be incompatible; however, only 6 of these (31%) had absorbance readings greater than 0.010 when the visual incompatibility was first observed. There was no physical evidence of incompatibility for several drug combinations that have been listed as incompatible in commonly used references. Turbidimetry does not appear to be as reliable a method for determining the compatibility of drugs as is visual inspection against a dark and a light background.