Institution
American Pharmacists Association
Other•Washington D.C., District of Columbia, United States•
About: American Pharmacists Association is a other organization based out in Washington D.C., District of Columbia, United States. It is known for research contribution in the topics: Pharmacist & Pharmacy. The organization has 2413 authors who have published 1969 publications receiving 30470 citations. The organization is also known as: APhA & American Pharmaceutical Association.
Topics: Pharmacist, Pharmacy, Population, Health care, Clinical pharmacy
Papers published on a yearly basis
Papers
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TL;DR: The increased utilization of generics, coupled with lower expenditure/DDDs for the classes, led to reduced reimbursed expenditure for the proton pump inhibitors, statins and newer antidepressants over time, providing direction to other European countries, especially those with higher expenditures/ DDDs for generics.
Abstract: Aim: To assess the impact of recent national and regional initiatives on the utilization and expenditure of four high-volume classes to provide future guidance. These were proton pump inhibitors, statins and ezetimibe, and renin–angiotensin drugs, as well as newer antidepressants. Methods: An observational study of prescriptions dispensed in ambulatory care in Catalonia was conducted from 2003 to 2007. Utilization was converted into defined daily doses (DDDs) and DDDs per 1000 inhabitants per day, and compared over the study period, as well as with other European countries. Results: As expected, there was increasing utilization of statins and renin–angiotensin drugs during the study period, as well as increased utilization of generics versus originators in each class; the latter figures were substantially greater than those published previously. There was also increased utilization of the proton pump inhibitors, which is a cause for concern. There were substantial reductions in the expenditure/DDDs of gen...
46 citations
Woolcock Institute of Medical Research1, University of Porto2, University of Beira Interior3, University of Naples Federico II4, Medical University of Warsaw5, Lithuanian University of Health Sciences6, American Pharmacists Association7, Scottish Government8, Karolinska University Hospital9, University of North Carolina at Chapel Hill10, Transylvania University11, Ghent University Hospital12, Buck Consultants13, Odense University Hospital14, McMaster University15, Humanitas University16, University of South Florida17, Leiden University Medical Center18, University of Minho19, Federal University of Bahia20, University of Montpellier21, University of Paris22, Université Paris-Saclay23, Saint Louis University24, Ain Shams University25, University of Chile26, University of Helsinki27, Katholieke Universiteit Leuven28, Ukrainian Medical Stomatological Academy29, University of Würzburg30, Charité31, Medical University of Łódź32, Vilnius University33, Oslo University Hospital34, Rashid Hospital35, Biomax Informatics AG36, University of Coimbra37, Royal College of Surgeons in Ireland38, University of Cologne39, University of Barcelona40, Johns Hopkins University41, Russian National Research Medical University42, Nippon Medical School43, Monash University44, Chiba University45, Charles University in Prague46, University of Manchester47, National and Kapodistrian University of Athens48, Ajou University49, University of Marburg50, Boston Children's Hospital51, University of Cape Town52, University of Crete53, Medical University of Graz54, Emek Medical Center55, University of Edinburgh56, University of Salerno57, University of Toronto58, European Union of Medical Specialists59, University of Turku60, University of Bari61, Nova Southeastern University62, Uppsala University63, Harvard University64, Celal Bayar University65, Catholic University of Cordoba66, Beijing Tongren Hospital67, Humboldt University of Berlin68
TL;DR: This paper builds on existing studies and provides tools intended to help pharmacists provide optimal advice/interventions/strategies to patients with rhinitis, including a diagnostic questionnaire specifically focusing attention on key symptoms and markers of the disease.
Abstract: Pharmacists are trusted health care professionals. Many patients use over-the-counter (OTC) medications and are seen by pharmacists who are the initial point of contact for allergic rhinitis management in most countries. The role of pharmacists in integrated care pathways (ICPs) for allergic diseases is important. This paper builds on existing studies and provides tools intended to help pharmacists provide optimal advice/interventions/strategies to patients with rhinitis. The Allergic Rhinitis and its Impact on Asthma (ARIA)-pharmacy ICP includes a diagnostic questionnaire specifically focusing attention on key symptoms and markers of the disease, a systematic Diagnosis Guide (including differential diagnoses), and a simple flowchart with proposed treatment for rhinitis and asthma multimorbidity. Key prompts for referral within the ICP are included. The use of technology is critical to enhance the management of allergic rhinitis. However, the ARIA-pharmacy ICP should be adapted to local healthcare environments/situations as regional (national) differences exist in pharmacy care.
46 citations
TL;DR: There is some evidence that prescription drug monitoring programs are a benefit to both law enforcement and health care delivery, but the programs have strengths and weaknesses, and their overall impact on drug abuse and illegal activity remains unclear.
Abstract: In response to increasing abuse of prescription drugs, forty-four states have implemented—and five more states will soon adopt—monitoring programs to track prescriptions of controlled medications. Although these programs were originally designed to help law enforcement officials and regulatory agencies spot possible illegal activity, health care providers have begun to use data from them to help improve patient safety and quality of care. For this article we reviewed government documents, expert white papers, articles from the peer-reviewed medical literature, and reports of the experiences of local health officials. We found some evidence that prescription drug monitoring programs are a benefit to both law enforcement and health care delivery. However, the programs have strengths and weaknesses, and their overall impact on drug abuse and illegal activity remains unclear. We believe that improving the efficacy of prescription drug monitoring programs will require such changes as more standardization and i...
45 citations
TL;DR: MRF provided by community pharmacists might be an effective strategy to balance the assurance of the benefit from medications and the avoidance of medication-related hospitalizations in aged patients using polypharmacy.
Abstract: Aims
The aims were to assess the impact of a medication review with follow-up (MRF) service provided in community pharmacy to aged polypharmacy patients on the number of medication-related hospital admissions and to estimate the effect on hospital costs
Methods
This was a sub-analysis of a cluster randomized controlled trials carried out in 178 community pharmacies in Spain Pharmacies in the intervention group (IG) provided a comprehensive medication review during 6 months Pharmacists in the comparison group (CG) delivered usual care For the purposes of this sub-analysis, an expert panel of three internal medicine specialists screened the hospitalizations occurring during the main study, in order to identify medication-related hospitalizations Inter-rater reliability was measured using Fleiss's kappa Hospital costs were calculated using diagnosis related groups
Results
One thousand four hundred and three patients were included in the main study and they had 83 hospitalizations Forty-two hospitalizations (506%) were medicine-related, with a substantial level of agreement among the experts (kappa = 065, 95% CI 052, 078, P < 001) The number of medication-related hospitalizations was significantly lower in patients receiving MRF (IG 11, GC 31, P = 0042) The probability of being hospitalized was 37 times higher in the CG (odds ratio 37, 95% CI 12, 113, P = 0021) Costs for a medicine-related hospitalization were €6672 Medication-related hospitalization costs were lower for patients receiving MRF [IG: €94 (SD 917); CG: €301 (SD 2102); 95% CI 359, 3780, P = 0018]
Conclusion
MRF provided by community pharmacists might be an effective strategy to balance the assurance of the benefit from medications and the avoidance of medication-related hospitalizations in aged patients using polypharmacy
45 citations
TL;DR: It is concluded that fluconazole was the highly probable cause of the development of torsade de pointes in a 33-year-old woman with a 5 year history of systemic lupus erythematosus, which recurred several weeks later when the patient was treated with flu Conazole for a second time and disappeared again on withdrawal of the drug.
Abstract: Objective:To describe a patient who developed torsade de pointes while being treated with fluconazoleCase Summary:A 33-year-old woman with a 5 year history of systemic lupus erythematosus was admitted to the intensive care unit because of respiratory insufficiency due to Candida albicans pneumonia Therapy with intravenous fluconazole 200 mg/day, with dose later adjusted according to her renal function, was started Prolongation of the QTc interval and torsade de pointes occurred Initially, domperidone, which had been initiated the day before fluconazole, was suspected as the possible cause and was discontinued; ultimately, both drugs were discontinued However, torsade de pointes recurred several weeks later when the patient was treated with fluconazole for a second time and disappeared again on withdrawal of the drug According to the Naranjo probability scale, this adverse reaction was highly probableDiscussion:The risk of torsade de pointes does not correlate in a linear fashion with prolongation o
45 citations
Authors
Showing all 2426 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| David Taylor | 131 | 2469 | 93220 |
| John Strang | 76 | 651 | 22873 |
| Antoine C. G. Egberts | 67 | 279 | 13896 |
| David M. Burger | 61 | 575 | 18170 |
| Helmut Schmidt | 59 | 366 | 13775 |
| Helene McNulty | 49 | 222 | 7184 |
| Lutz Heide | 48 | 182 | 6627 |
| Larry H. Danziger | 43 | 170 | 6546 |
| Abu T.M. Serajuddin | 42 | 128 | 8165 |
| Leslie Hendeles | 42 | 220 | 6364 |
| Cynthia A. Jackevicius | 42 | 179 | 6826 |
| Vincent Launay-Vacher | 41 | 220 | 5981 |
| Ron A. A. Mathot | 36 | 76 | 3032 |
| L. Lee Dupuis | 35 | 201 | 5106 |
| George A. Kenna | 33 | 63 | 2528 |