Bishop Heber College

About: Bishop Heber College is a based out in . It is known for research contribution in the topics: Thin film & Band gap. The organization has 548 authors who have published 692 publications receiving 7144 citations.

Silver-chitosan nanoparticles induced biochemical variations of chickpea (Cicer arietinum L.)

Abstract: Chitosan-silver (Ag-CS) nanoparticles were synthesized and their physico-chemical characterization was carried out by DLS, TEM and FTIR. The study highlighted the reduced size (20–50 nm)and mono-disperse nature of Ag-CS Nps. Experiments were carried out to study the efficacy of Ag-CS Nps on chickpea seeds. Laboratory synthesized nanoparticles (0.1%, w/v) showed substantial growth promotory effect on chickpea seed germination, seedling length, fresh and dry weight. Regarding the pigment content, nanoparticles treated seedlings showed a remarkable increase of chlorophyll. A consequential increase in enzyme activity including α, β-amylase, ascorbate peroxidase (APX), peroxidase (POD) and catalase (CAT) was observed with nanoparticle treatment. In addition, Ag-CS Nps showed higher expression of MDA content. The overall results confirm the significant growth promotory effect as well as biochemical variation capabilities of Ag-CS Nps. This study opens up the possibility to use Ag-CS Nps as growth promotors in chickpea under the pot and field condition with the knowledge of toxicity levels.

A comprehensive study on cloud computing

Abstract: Cloud computing plays the promising role in recent technology. Many companies are involved themselves in this computing to enjoy full-fledged services. But now the situation are not like that because of security issues. Security issues reduce the growth of the computing. In this paper we are surveying the security related issue and also we discuss the available technique to eradicate the issues. This work aims to provide the ways to reduce the security risk and also promote the performance of the cloud computing.

Electrochemical investigation of Zr-doped ZnO nanostructured electrode material for high-performance supercapacitor

Abstract: Simple electrochemical capacitors are promising energy storage devices because of their power capability, charge/discharge rates and life cycle. Zinc oxide is an inexpensive and eco-friendly material which can be used as a supercapacitor electrode relative to other materials with great features. With a view to enhance the electrochemical performance of ZnO (Csp of 324), the present work is focused to synthesize modified ZnO nanostructures by the dopant Zr in three different compositions (3, 6 and 9 wt% Zr-doped ZnO) via chemical coprecipitation method. The synthesized materials were characterized by physio-chemical methods. The significant capacitive behaviour of ZnO and modified ZnO and 9 wt%Zr-doped ZnO nanostructure were investigated by cyclic voltammetric (CV) studies, galvanostatic charge-discharge (GCD) analysis and electrochemical impedance spectroscopic (EIS) methods in aqueous 1 M KOH. The newly fabricated 9 wt% Zr-doped ZnO electrode exhibited excellent specific capacitance of 518 Fg−1 at a current density of 1 Ag−1. Additionally, it depicted the capacitance retention of 94% even after 5000 successive GCD cycles. Moreover, the as-prepared materials demonstrated electrochemical reversible nature.

Determination of 8-hydroxy-2′-deoxyguanosine oxidative stress biomarker using dysprosium oxide nanoparticles@reduced graphene oxide

Abstract: 8-Hydroxy-2′-deoxyguanosine (8-OHdG) is a risk factor; it plays a crucial role in inducing oxidative stress involved in the physiological processes and it is a biomarker in the response to human disease and injury. Therefore, the development of a robust, low-cost, and portable analytical tool for quantification of 8-hydroxy-2′-deoxyguanosine in human blood and urine samples is required. It is essential to diagnose oxidative stress-related diseases in human body. For this purpose, herein, we report an electrochemical sensor based on Dy2O3 nanoparticle-decorated reduced graphene oxide nanocomposite (Dy2O3 NPs@RGO). A microwave-assisted synthetic route was adopted to prepare Dy2O3 NPs@RGO. Subsequently, its morphological, elemental, and crystal structure properties were analyzed. Electrochemical and interfacial properties were examined to ensure the material's suitability in electrocatalytic sensing. Dy2O3 NPs@RGO-affixed conventional screen-printed electrode (SPCE) was found to exhibit tremendous electrocatalytic capability toward 8-OHdG oxidation. A sensitive and reproducible sensor for the amperometric detection of 8-OHdG was fabricated, which could detect concentrations as low as 1.02 nM. The method worked well even in real samples (human urine and blood serum), and the results were validated by the HPLC method, indicating the reliability of the proposed method in clinical analysis.

Isatin based macrocyclic Schiff base ligands as novel candidates for antimicrobial and antioxidant drug design: In vitro DNA binding and biological studies.

Abstract: In the present work, five macrocyclic compounds, C18H12N2O4 (1), C38H24N8O6 (1a), C38H24N8O4S2 (1b), C40H32N8O4 (2a) and C48H32N8O4 (2b) have been synthesized and thoroughly characterized by elemental analysis, FT-IR, 1D & 2D NMR and electron spray ionization mass spectral analysis. The DNA binding ability of these compounds were investigated in vitro by UV-Visible, fluorescence, circular dichroism (CD) spectroscopy and viscosity measurements. The results indicate that these compounds possess strong DNA binding affinity via intercalation, while the order of binding strength followed the trend 2b (1.52 ± 0.06 × 105 M-1) > 2a (1.12 ± 0.11 × 105 M-1) > 1b (1.05 ± 0.04 × 105 M-1) > 1a (0.97 ± 0.14 × 104 M-1) > 1 (0.75 ± 0.21 × 104 M-1). The radical scavenging potencies of the compounds were explored by employing DPPH, OH and NO assays, in which 1a exhibited highest inhibitory effect on the radicals (IC50 = 23.59 μM (DPPH), 26.14 μM (OH), 28.41 μM (NO)). The in vitro antibacterial studies showed that these compounds have the potential to arrest the growth of bacteria, among which, 1a was found to be vulnerable against the bacterial stains. In addition, in silico molecular docking stimulations were also performed to position these compounds into the active sites of bacterial membrane proteins. The results of in vitro and in silico investigations reveal that the compounds apprehend the bacterial growth significantly. The data obtained from this piece of work would be helpful to design antibacterial drugs incorporating isatin based macrocyclic frameworks.