Bishop Heber College

About: Bishop Heber College is a based out in . It is known for research contribution in the topics: Thin film & Band gap. The organization has 548 authors who have published 692 publications receiving 7144 citations.

Computational gene expression profiling in the exploration of biomarkers, non-coding functional RNAs and drug perturbagens for COVID-19.

Abstract: The coronavirus disease, caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), is a global health crisis that is being endured with an increased alarm of transmission each day. Though the pandemic has activated innumerable research attention to decipher an antidote, fundamental understanding of the molecular mechanisms is necessary to halt the disease progression. The study focused on comparison of the COVID-19 infected lung tissue gene expression datasets -GSE155241 and GSE150316 with the GEO2R-limma package. The significant up- and downregulated genes were annotated. Further evaluation of the enriched pathways, transcription factors, kinases, noncoding RNAs and drug perturbations revealed the significant molecular mechanisms of the host response. The results revealed a surge in mitochondrial respiration, cytokines, neurodegenerative mechanisms and deprived oxygen, iron, copper, and glucose transport. Hijack of ubiquitination by SARS-CoV-2, hox gene differentiation, histone modification, and miRNA biogenesis were the notable molecular mechanisms inferred. Long non-coding RNAs such as C058791.1, TTTY15 and TPTEP1 were predicted to be efficient in regulating the disease mechanisms. Drugs-F-1566-0341, Digoxin, Proscillaridin and Linifanib that reverse the gene expression signatures were predicted from drug perturbations analysis. The binding efficiency and interaction of proscillaridin and digoxin as obtained from the molecular docking studies confirmed their therapeutic potential. Two overlapping upregulated genes MDH1, SGCE and one downregulated gene PFKFB3 were appraised as potential biomarkers candidates. The upregulation of PGM5, ISLR and ANK2 as measured from their expressions in normal lungs affirmed their possible prognostic biomarker competence. The study explored significant insights for better diagnosis, and therapeutic options for COVID-19.Communicated by Ramaswamy H. Sarma.

Effect of sputtering power on properties and photovoltaic performance of CIGS thin film solar cells

Abstract: CuInGaS2 (CIGS) thin films were fabricated by DC magnetron sputtering by varying the sputtering power (70, 90, 110 and 130 W). The X-ray diffraction revealed the formation of tetragonal structure with (1 1 2) preferential orientation. The film prepared at 90 W has better crystallinity with minimum dislocation density and strain. From the scanning electron microscopy analysis, it was found to be a denser and larger in grain formation. The elemental quantification and stoichiometric ratio of the CIGS films were confirmed by energy-dispersive spectra. The optical band gap was found using Tauc plot, and it varied from 1.20 to 1.52 eV. The transport conduction mechanism involved in CIGS films was identified from DC four-probe method. Raman studies reveal that all the films composed of CH and CA ordering. The solar cell measurements indicate that high power conversion efficiency (η) of 0.29% and short-circuit current density of (Jsc) of 4.51 mA/cm2 obtained for the film deposited at 90 W.

A Framework for Mobile Payment Consortia System (MPCS)

Abstract: Researches in mobile commerce have increased significantly with the emphasis on identifying new applications, designing frameworks, and engineering network solutions. Mobile payment is a natural successor to Web centric payments which has emerged as one of the sub domains of mobile commerce applications. A study reveals that there are wide ranges of mobile payment solutions and models which are available with the aid of various services such as short message service (SMS), but there is no specific mobile payment system for educational institutions to collect the fees as well as for student community to pay the fees without huge investment. This paper proposes a novel model called mobile payment consortia system to carry out the transactions from the bank to the academic institutions for the payment of fees by students through mobile phone. Mobile Payment Consortia System provides end-to-end security using symmetric signature scheme while carrying out the payment transactions. This system increases convenience in payment processes and reduces transactional cost for both students and educational institutions. Mobile payment consortia system (MPCS) is a model specifically designed to make payments and financial services in particular payment of fees by students from the customerpsilas bank to the institutionpsilas bank where they study using mobile device anytime and anywhere.