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Institution

Czechoslovak Academy of Sciences

Government
About: Czechoslovak Academy of Sciences is a based out in . It is known for research contribution in the topics: Catalysis & Adsorption. The organization has 13227 authors who have published 17335 publications receiving 272882 citations.


Papers
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Journal ArticleDOI
TL;DR: An electrophysiological study shows that the motor nerve at the third day after injury forms synaptic contacts with regenerating muscle cells, and the regeneration process has proceeded to the stage of early muscle fibres with fully differentiated myofibrils with typical sarcomere structures.
Abstract: Methyl-bupivacaine is a local anaesthetic with a selective myotoxic action. A single subcutaneous injection of the drug into the hind leg of adult rats produces a uniform, complete and irreversible destruction of superficial layers of fibres in the underlying extensor digitorum longus muscle. The degeneration of muscle fibres is followed by phagocytosis and a rapid and complete regeneration. The first stage in the regeneration process is the appearance of presumptive myoblasts within the original basement membrane of the sarcolemmal tube. On the second day after injury aggregates of myoblasts are present and fusion is observed between the cells. The myotubes thus formed increase in size by fusing with additional myoblasts. Myotubes are also observed to fuse with one another. On the fifth day after injury the regeneration process has proceeded to the stage of early muscle fibres with fully differentiated myofibrils with typical sarcomere structures. By ten days only mature muscle fibres of about normal size are present and regeneration appears complete. In previously denervated and methyl-bupivacaine treated muscles the stages of regeneration are similar to those observed in innervated muscles, the only apparent difference being a slowing of cell differentiation and incomplete maturation. An electrophysiological study shows that the motor nerve at the third day after injury forms synaptic contacts with regenerating muscle cells. At that stage of myogenesis the myotubes are highly sensitive to applied acetylcholine. 1 (1-n-butyl-DL-piperidine-2-carboxylic acid-2,6-dimethyl-anilide-hydrochloride); Marcaine®, manufactured by AB Bofors, Nobel-Pharma, Molndal, Sweden.

127 citations

Journal ArticleDOI
TL;DR: In this paper, the authors derived from directionally independent representative P-wave residuals, are in good agreement with magnetotelluric determinations of a layer with increased conductivity in the upper mantle.

127 citations

Journal ArticleDOI
TL;DR: In this paper, the distribution of ADR bound to N -(2-hydroxypropyl)methacrylamide (HPMA) copolymers via biodegradable (Gly-Phe-Leu-Gly) oligopeptide sequences was examined.

127 citations

Journal ArticleDOI
TL;DR: In this paper, a critical evaluation of adsorptive accumulation in stripping analysis, with differential pulse polarography for the measurement step, is described, and generally applicable conditions for this method are given.

126 citations

Journal ArticleDOI
TL;DR: In this paper, the adsorption and oxidation of adsorbed sulphur and of sulphur dioxide on a smooth platinum electrode have been studied by the potentiodynamic method.

126 citations


Authors

Showing all 13227 results

NameH-indexPapersCitations
Milos Lokajicek139151198888
Bo K. Siesjö11346946151
Pavel Hobza10756448080
Robin A. Weiss9433236744
Frantisek Svec9241625688
Stefano Schiaffino8623333691
Farooq Azam8521936142
Jan Vilcek8235326148
David C. Klein8034324219
David L. Denlinger7833819283
Josef Michl7785228731
Henry C. Pitot7646425024
Jindřich Kopeček7634319913
Lynn Nadel7521430376
Petr Novák7551930962
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20222
20211
20149
20135
20119
201019