DAV College, Chandigarh

About: DAV College, Chandigarh is a based out in . It is known for research contribution in the topics: Radon & Adsorption. The organization has 349 authors who have published 676 publications receiving 6233 citations.

Metal assisted approach to develop molecularly imprinted mesoporous material exhibiting pockets for the fast uptake of diethyl phthalate as copper complex.

Abstract: A new molecularly imprinted mesoporous material (MIM) containing specific pockets for the extraction of diethyl phthalate (DEP) as copper complex has been prepared for the first time. The mesoporous material was developed by utilizing copper-phthalate complex (Cu-DEP) as the template molecule, 3-aminopropyltriethoxysilane (APS) as a functional monomer and tetraethoxyorthosilicate (TEOS) as the silica source for polymer network formation. The mesoporous material showed fast uptake kinetics, and equilibrium was obtained within 30 min due to the introduction of copper, which provides an additional site for interaction with the functional monomer. Synthesized polymer was well characterized using UV-Vis spectrophotometry, IR spectroscopy, TGA studies, and TEM. To achieve efficient extraction of the template molecule, various factors including sorption kinetics, quantity of MIM, time required for equilibrium set-up, sorption isotherm and reuse of MIM were optimized. The extracted DEP samples were analyzed quantitatively at 310 nm using an HPLC-DA system. The prepared material is robust and can be reused. In addition, it was found to be selective for DEP as compared to other phthalates.

Mononuclear Pseudostannatranes Possessing Unsymmetrical [4.4.3.01,5]Tridecane Cage: Experimental and Theoretical Aspects of Reverse Kocheshkov Reaction in Phenyl Pseudostannatrane.

Abstract: The synthetic protocols, structural aspects, and spectroscopic aspects of mononuclear pseudostannatranes possessing a [4.4.3.01,5]tridecane cage have been reported. A tripodal ligand N(CH2CH2OH){CH...

Triarylethylene-indolin-2,3-dione molecular conjugates: design, synthesis, docking studies and anti-proliferation evaluation

Abstract: A series of 1H-1,2,3-triazole-linked ospemifene-isatin and O-methylated ospemifene–isatin conjugates were synthesized and assayed for their anti-proliferative activities against estrogen-responsive as well as estrogen-non-responsive cells. The non-cytotoxic conjugate 14e, with an optimal combination of bromo substituents at the C-5/C-7 positions of isatin, proved to be a promising hit with an IC50 value of 31.62 μM against MCF-7 and 19.23 μM against MDA-MB-231. The observed anti-proliferative activities of active conjugates were further corroborated via docking studies carried out on estrogen receptor subtypes α and β.

MX/G/1 state dependent arrival queue with optional service and vacation under randomised policy

Abstract: The present study deals with the performance analysis of a single server queues with state dependent arrival rates in batches. It is considerable that the units join the system for essential and optional services available in the system. The server can avail the at most m-vacations under randomised vacations policy. The system is analysed by using the supplementary variable technique with the assumptions of probability reasoning for study the steady state behaviour of the system and to obtain various performance indices of queue size distribution. The maximum entropy principle is used to find the approximate results of performance measures and comparative study of exact and approximate waiting times of the units is discussed. The numerical illustration is also carried out to facilitate the minimum cost for optimal parameters and validate the other results of the system.

Assessment of Metal(loid) Contamination and Genotoxic Potential of Agricultural Soils.

Abstract: Soil, a connecting link between biotic and abiotic components of terrestrial ecosystem, receives different kinds of pollutants through various point and nonpoint sources. Among different sources of soil pollution, contaminated irrigation water is one of the most prominent sources affecting soils throughout the globe. The irrigation water (both surface and groundwater) is increasingly getting polluted with contaminants such as metal(loid)s due to various anthropogenic activities. The present study was conducted to analyze metal(loid) contents in agricultural soil samples (N = 24) collected from fields along the banks of rivers Beas and Sutlej flowing through Punjab state of India, using wavelength-dispersive X-ray fluorescence (WDXRF) spectroscopy. The soil samples were also analyzed for their genotoxic potential using Allium cepa root chromosomal aberration assay. The rivers Beas and Sutlej are contaminated with municipal and industrial effluents in different parts of Punjab. The soil samples analyzed were found to have higher contents of arsenic, cobalt and chromium in comparison with the reference values given by various international agencies. Pollution assessment using different indices like index of geo-accumulation, enrichment factor and contamination factor revealed that the soil samples were highly polluted with cobalt and arsenic. The Allium cepa assay revealed that maximum genotoxicity was found in soil samples having higher contents of As and Co. Pearson’s correlation analysis revealed strong positive correlation between the different metal(loid)s which indicated common sources of these metal(loid)s. Therefore, efforts must be taken to reduce the levels of these metal(loid)s in these agricultural soils.