Institution
Duquesne University
Education•Pittsburgh, Pennsylvania, United States•
About: Duquesne University is a education organization based out in Pittsburgh, Pennsylvania, United States. It is known for research contribution in the topics: Population & Health care. The organization has 3615 authors who have published 7169 publications receiving 180066 citations. The organization is also known as: Duquesne University of the Holy Spirit.
Papers published on a yearly basis
Papers
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TL;DR: 6MWT performance in persons with multiple sclerosis was explained by balance confidence (ABC) and stair-climbing ability (FST) and may be practical clinical measures for explaining walking ability and determining risk for disablement in people with MS.
Abstract: Purpose: The primary purpose of this study was to determine the extent to which health factors, functional measures, and pulmonary impairment explain performance on 6-Minute Walk Test (6MWT) distance in ambulatory persons with multiple sclerosis (MS). Another purpose was to determine the effect of disability and age on 6MWT performance and explanatory factors.
Methods: A cross-sectional study design was used to evaluate factors that explain performance on the 6MWT in 64 community-dwelling persons with MS-related disability (Expanded Disability Status Scale [EDSS] 3.8±1.6). Of the 64 participants, 43 (67.2%) exhibited mild disability (EDSS <4.0) and 21 (32.8%) had moderate disability (EDSS 4.0–6.5). A regression analysis compared 6MWT performance to measures of health factors (EDSS, number of medications, number of comorbidities, resting HR, systolic and diastolic blood pressure [BP]); physical performance (functional stair test [FST], sit-to-stand test [SST], static standing balance [BAL], Fatigue Severity Scale [FSS], Activities-specific Balance Confidence [ABC] Scale); and pulmonary function (forced expiratory volume in 1 second [FEV1], forced vital capacity [FVC], maximal voluntary ventilation [MVV], maximal inspiratory pressure [MIP], maximal expiratory pressure [MEP]).
Results: EDSS, ABC, FST, SST, BAL, MVV, MIP, and MEP were significantly associated with 6MWT distance after adjusting for age. Multiple step-wise linear regression analysis revealed that ABC, FST, and BAL were significant and independent explanatory factors of 6MWT distance. ABC and FST explained 75% of the variance in 6MWT performance (R2=0.75). Curvilinear regression analysis revealed that the FST is the most significant explanatory factor for 6MWT distance, explaining 79% of the variance (R2=0.79).
Conclusions: 6MWT performance in persons with MS was explained by balance confidence (ABC) and stair-climbing ability (FST). The ABC and FST may be practical clinical measures for explaining walking ability and determining risk for disablement in persons with MS.
67 citations
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67 citations
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TL;DR: A novel RNA-dependent repair mechanism of DSBs in post-mitotic neurons is shown and it is demonstrated that defects in this pathway may contribute to neuronal genomic instability and consequent neurodegenerative phenotypes such as those seen in Alzheimer's disease.
67 citations
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TL;DR: The findings provide evidence of compensatory increases in SHR due to pain associated with full-thickness rotator cuff tear, and the contribution of glenohumeral elevation increased significantly whereas scapular upward and downward rotation tended to decrease.
67 citations
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TL;DR: In this article, a course on classroom assessment is compared to an introductory psychometrics course, and the authors discuss the role of instruction concerning grading and communicating in such a course.
Abstract: How should a course on classroom assessment differ from an introductory psychometrics course? How should such a course be taught? How large a role should instruction concerning grading and communicating play in such a course?
67 citations
Authors
Showing all 3668 results
Name | H-index | Papers | Citations |
---|---|---|---|
Krzysztof Matyjaszewski | 169 | 1431 | 128585 |
William L. Jorgensen | 108 | 586 | 95112 |
John C. Avise | 105 | 413 | 53088 |
Rongchao Jin | 101 | 332 | 42920 |
Paul Knochel | 99 | 2373 | 44786 |
Gwendolen Jull | 87 | 410 | 26556 |
Hugh M. Robertson | 83 | 197 | 27173 |
Peter Wipf | 83 | 767 | 25316 |
Ivet Bahar | 78 | 391 | 24228 |
Luk N. Van Wassenhove | 78 | 322 | 29163 |
Carl H. Snyderman | 76 | 481 | 22390 |
Ronald S. Oremland | 76 | 198 | 19671 |
Jeffrey L. Brodsky | 71 | 256 | 18315 |
Maarten J. Postma | 62 | 753 | 33409 |
Alan J. Russell | 62 | 280 | 13894 |