Institution
Huddersfield Royal Infirmary
Healthcare•Huddersfield, United Kingdom•
About: Huddersfield Royal Infirmary is a healthcare organization based out in Huddersfield, United Kingdom. It is known for research contribution in the topics: Randomized controlled trial & Glaucoma surgery. The organization has 430 authors who have published 335 publications receiving 7538 citations.
Papers published on a yearly basis
Papers
More filters
••
TL;DR: This is the first randomised placebo-controlled trial to show preservation of the visual field with an intraocular-pressure-lowering drug in patients with open-angle glaucoma, and visual field preservation was significantly longer in the latanoprost group than in the placebo group.
453 citations
••
TL;DR: There is some evidence to suggest that the method of payment of primary care physicians affects their behaviour, but the findings' generalisability is unknown, especially in terms of the relative impact of salary versus capitation payments.
Abstract: Background
It is widely believed that the method of payment of physicians may affect their clinical behaviour. Although payment systems may be used to achieve policy objectives (e.g. cost containment or improved quality of care), little is known about the effects of different payment systems in achieving these objectives.
Objectives
To evaluate the impact of different methods of payment (capitation, salary, fee for service and mixed systems of payment) on the clinical behaviour of primary care physicians (PCPs).
Search methods
We searched the Cochrane Effective Practice and Organisation of Care Group specialised register; the Cochrane Controlled Trials Register; MEDLINE (1966 to October 1997); BIDS EMBASE (1980 to October 1997); BIDS ISI (1981 to October 1997); EconLit (1969 to October 1997); HealthStar (1975 to October 1997) Helmis (1984 to October 1997); health economics discussion paper series of the Universities of York, Aberdeen, Sheffield, Bristol, Brunel, and McMaster; Swedish Institute of Health Economics; RAND corporation; and reference lists of articles.
Selection criteria
Randomised trials, controlled before and after studies and interrupted time series analyses of interventions comparing the impact of capitation, salary, fee for service (FFS) and mixed systems of payment on primary care physician satisfaction with working environment; cost and quantity of care; type and pattern of care; equity of care; and patient health status and satisfaction.
Data collection and analysis
Two reviewers independently extracted data and assessed study quality.
Main results
Four studies were included involving 640 primary care physicians and more than 6400 patients. There was considerable variation in study setting and the range of outcomes measured. FFS resulted in more primary care visits/contacts, visits to specialists and diagnostic and curative services but fewer hospital referrals and repeat prescriptions compared with capitation. Compliance with a recommended number of visits was higher under FFS compared with capitation payment. FFS resulted in more patient visits, greater continuity of care, higher compliance with a recommended number of visits, but patients were less satisfied with access to their physician compared with salaried payment.
Authors' conclusions
It is noteworthy that so few studies met the inclusion criteria. There is some evidence to suggest that the method of payment of primary care physicians affects their behaviour, but the findings' generalisability is unknown. More evaluations of the effect of payment systems on PCP behaviour are needed, especially in terms of the relative impact of salary versus capitation payments.
428 citations
••
TL;DR: There is some evidence to suggest that how a primary care physician is paid does affect his/her behaviour but the generalisability of these studies is unknown and most policy changes in the area of payment systems are inadequately informed by research.
Abstract: Objective: To review the impact of payment systems on the behaviour of primary care physicians.Methods: All randomised trials, controlled before and after studies, and interrupted time series studies that compared capitation, salary, fee-for-service or target payments (mixed or separately) that were identified by computerised searches of the literature. Methodological quality assessment and data extraction were undertaken independently by two reviewers using a data checklist. Study results were qualitatively analysed.Results: Six studies met the inclusion criteria. There was considerable variation in the quality of reporting, study setting and the range of outcomes measured. Fee-for-service resulted in a higher quantity of primary care services provided compared with capitation but the evidence of the impact on the quantity of secondary care services was mixed. Fee-for-service resulted in more patient visits, greater continuity of care, higher compliance with a recommended number of visits, but lower pati...
313 citations
••
TL;DR: Higher BPA levels inPCOS women compared to controls and a statistically significant positive association between androgens and BPA point to a potential role of this endocrine disruptor in PCOS pathophysiology.
Abstract: This article appears in The Journal of Clinical Endocrinology & Metabolism, published December 30, 2010, 10.1210/jc.2010-1658
304 citations
••
TL;DR: This work discovers and validate six previously unknown risk loci for PBC and used pathway analysis to identify JAK-STAT/IL12/IL27 signalling and cytokine–cytokine pathways, for which relevant therapies exist.
Abstract: Primary biliary cirrhosis (PBC) is a classical autoimmune liver disease for which effective immunomodulatory therapy is lacking. Here we perform meta-analyses of discovery data sets from genome-wide association studies of European subjects (n=2,764 cases and 10,475 controls) followed by validation genotyping in an independent cohort (n=3,716 cases and 4,261 controls). We discover and validate six previously unknown risk loci for PBC (Pcombined<5 × 10(-8)) and used pathway analysis to identify JAK-STAT/IL12/IL27 signalling and cytokine-cytokine pathways, for which relevant therapies exist.
245 citations
Authors
Showing all 430 results
Name | H-index | Papers | Citations |
---|---|---|---|
John Gregory | 59 | 283 | 15498 |
Wyn G. Lewis | 35 | 207 | 4386 |
David Mitchell | 24 | 89 | 1865 |
Ippokratis Pountos | 23 | 63 | 1918 |
Richard Reece | 21 | 26 | 2421 |
Felicity Astin | 21 | 76 | 1606 |
Eleni Kandaraki | 21 | 40 | 1474 |
Johnathan Joffe | 20 | 52 | 3138 |
Nitin Anand | 19 | 71 | 1318 |
Richard Fuller | 15 | 42 | 824 |
Marilynne N. Kirshbaum | 14 | 57 | 612 |
Stephen G Oxberry | 13 | 27 | 785 |
Y G Karagama | 12 | 21 | 339 |
Rohit Rambani | 11 | 27 | 315 |
Ayman S. Abdelrazeq | 11 | 13 | 392 |