Institution
Kazan Federal University
Education•Kazan’, Russia•
About: Kazan Federal University is a education organization based out in Kazan’, Russia. It is known for research contribution in the topics: Population & Chemistry. The organization has 9868 authors who have published 14390 publications receiving 135726 citations. The organization is also known as: Kazan (Volga region) Federal University & Kazan State University.
Papers published on a yearly basis
Papers
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TL;DR: In this paper, the composition and molecular mass distribution of n-alkanes in asphaltenes of crude oils of different ages and in wax deposits formed in the borehole equipment were studied.
40 citations
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TL;DR: The level of grid refinement characterizes the multiplicity of the grid step splitting and strong dependence of the permeability coefficients on the grid refinement level was revealed for each mathematical model.
40 citations
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TL;DR: The achievements in analysis of information on chemical reactions using machine learning methods using computer-assisted planning of synthesis, analysis and visualization of chemical reaction data, prediction of the quantitative characteristics of reactions and computer-aided design of catalysts are reviewed.
Abstract: The review is devoted to the achievements in analysis of information on chemical reactions using machine learning methods. Four large areas that actively use these methods are outlined: computer-assisted planning of synthesis, analysis and visualization of chemical reaction data, prediction of the quantitative characteristics of reactions and computer-aided design of catalysts. http://dx.doi.org/10.1070/RCR4746
40 citations
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TL;DR: The hormone-mediated recruitment of cyclin D1 to sites of DDR may facilitate the resistance of prostate cancer cells to DNA damage therapies and highlight the need to explore other therapeutic approaches in prostate cancer to prevent or overcome drug resistance.
Abstract: Therapy resistance and poor outcome in prostate cancer is associated with increased expression of cyclin D1. Androgens promote DNA double-strand break repair to reduce DNA damage, and cyclin D1 was also shown to enhance DNA damage repair (DDR). In this study, we investigated the significance of cyclin D1 in androgen-induced DDR using established prostate cancer cells and prostate tissues from cyclin D1 knockout mice. We demonstrate that endogenous cyclin D1 further diminished the dihydrotestosterone (DHT)-dependent reduction of γH2AX foci in vitro. We also show that cyclin D1 was required for the androgen-dependent DNA damage response both in vitro and in vivo. Furthermore, cyclin D1 was required for androgen-enhanced DDR and radioresistance of prostate cancer cells. Moreover, microarray analysis of primary prostate epithelial cells from cyclin D1-deficient and wild-type mice demonstrated that most of the DHT-dependent gene expression changes are also cyclin D1 dependent. Collectively, our findings suggest that the hormone-mediated recruitment of cyclin D1 to sites of DDR may facilitate the resistance of prostate cancer cells to DNA damage therapies and highlight the need to explore other therapeutic approaches in prostate cancer to prevent or overcome drug resistance.
40 citations
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TL;DR: In this paper, the impacts of land use (organic farming, conventional farming and forest) on forms and distribution of P in soil were assessed and the authors concluded that land use and management practices such as crop rotation, residue input and farmyard manure application significantly increase different fractions of organic farming.
40 citations
Authors
Showing all 10096 results
Name | H-index | Papers | Citations |
---|---|---|---|
Richard G. Pestell | 130 | 479 | 54210 |
Alexander Spiridonov | 126 | 1198 | 77296 |
V. Stolyarov | 119 | 238 | 79004 |
Sergei D. Odintsov | 112 | 609 | 62524 |
Hans-Uwe Simon | 96 | 461 | 51698 |
Yuri Lvov | 89 | 342 | 27397 |
Alexei A. Starobinsky | 88 | 340 | 42331 |
Yakov Kuzyakov | 87 | 667 | 37050 |
V. E. Semenov | 74 | 372 | 22577 |
John W. Weisel | 73 | 323 | 17866 |
Klaus T. Preissner | 72 | 333 | 21289 |
Alexander Tropsha | 71 | 288 | 22898 |
Roland Winter | 68 | 468 | 15193 |
Christoph Schick | 68 | 443 | 16664 |
Marat Gilfanov | 62 | 350 | 14987 |