Institution
Kazan Federal University
Education•Kazan’, Russia•
About: Kazan Federal University is a education organization based out in Kazan’, Russia. It is known for research contribution in the topics: Population & Chemistry. The organization has 9868 authors who have published 14390 publications receiving 135726 citations. The organization is also known as: Kazan (Volga region) Federal University & Kazan State University.
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TL;DR: In this paper, the heat transfer oils dibenzyltoluene (dibenzyl-luene) and benzylluene (benzyluene) were used as a new class of liquid organic hydrogen carrier compounds.
Abstract: The heat transfer oils dibenzyltoluene and benzyltoluene are promising materials as a new class of liquid organic hydrogen carrier compounds (LOHC). Thermophysical properties (heat capacity, density, viscosity, and surface tension) of the commercially available thermofluids Marlothem LH (benzyltoluene) and Marlotherm SH (dibenzyltoluene) and their completely hydrogenated derivatives were measured. Thermochemical properties (enthalpies of combustion and enthalpies of vaporization) were derived from experiments. Gas-phase molar enthalpies of formation were derived and validated with group-additivity and high-level quantum chemical calculations. Enthalpies of the hydrogenation/dehydrogenation reactions of the LOHC pairs under study were derived.
172 citations
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TL;DR: The halloysite-doped scaffolds are biocompatible as demonstrated both in vitro and in vivo, and the chitosan-gelatine-agarose doped clay nanotube nanocomposite scaffolds fabricated in this work are promising candidates for tissue engineering applications.
Abstract: Porous biopolymer hydrogels doped at 3–6 wt% with 50 nm diameter/0.8 μm long natural clay nanotubes were produced without any cross-linkers using the freeze-drying method. The enhancement of mechanical strength (doubled pick load), higher water uptake and thermal properties in chitosan–gelatine–agarose hydrogels doped with halloysite was demonstrated. SEM and AFM imaging has shown the even distribution of nanotubes within the scaffolds. We used enhanced dark-field microscopy to visualise the distribution of halloysite nanotubes in the implantation area. In vitro cell adhesion and proliferation on the nanocomposites occur without changes in viability and cytoskeleton formation. In vivo biocompatibility and biodegradability evaluation in rats has confirmed that the scaffolds promote the formation of novel blood vessels around the implantation sites. The scaffolds show excellent resorption within six weeks after implantation in rats. Neo-vascularization observed in newly formed connective tissue placed near the scaffold allows for the complete restoration of blood flow. These phenomena indicate that the halloysite-doped scaffolds are biocompatible as demonstrated both in vitro and in vivo. The chitosan–gelatine–agarose doped clay nanotube nanocomposite scaffolds fabricated in this work are promising candidates for tissue engineering applications.
170 citations
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TL;DR: In this article, the scaling relation between Sunyaev-Zeldovich (SZ) signal and stellar mass for almost 260,000 locally brightest galaxies (LBGs) selected from the Sloan Digital Sky Survey (SDSS) was presented.
Abstract: We present the scaling relation between Sunyaev-Zeldovich (SZ) signal and stellar mass for almost 260,000 locally brightest galaxies (LBGs) selected from the Sloan Digital Sky Survey (SDSS). These are predominantly the central galaxies of their dark matter halos. We calibrate the stellar-to-halo mass conversion using realistic mock catalogues based on the Millennium Simulation. Applying a multi-frequency matched filter to the Planck data for each LBG, and averaging the results in bins of stellar mass, we measure the mean SZ signal down to M-* similar to 2 x 10(11) M-circle dot, with a clear indication of signal at even lower stellar mass. We derive the scaling relation between SZ signal and halo mass by assigning halo properties from our mock catalogues to the real LBGs and simulating the Planck observation process. This relation shows no evidence for deviation from a power law over a halo mass range extending from rich clusters down to M-500 similar to 2 x 10(13) M-circle dot, and there is a clear indication of signal down to M-500 similar to 4 x 10(12) M-circle dot. Planck's SZ detections in such low-mass halos imply that about a quarter of all baryons have now been seen in the form of hot halo gas, and that this gas must be less concentrated than the dark matter in such halos in order to remain consistent with X-ray observations. At the high-mass end, the measured SZ signal is 20 % lower than found from observations of X-ray clusters, a difference consistent with the magnitude of Malmquist bias effects that were previously estimated for the X-ray sample.
170 citations
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TL;DR: The MDE–FACS platform allowed the identification of human butyrylcholinesterase mutants that undergo self-reactivation after inhibition by the organophosphorus agent paraoxon and predicted which genera were associated with inhibitory activity.
Abstract: Ultrahigh-throughput screening (uHTS) techniques can identify unique functionality from millions of variants. To mimic the natural selection mechanisms that occur by compartmentalization in vivo, we developed a technique based on single-cell encapsulation in droplets of a monodisperse microfluidic double water-in-oil-in-water emulsion (MDE). Biocompatible MDE enables in-droplet cultivation of different living species. The combination of droplet-generating machinery with FACS followed by next-generation sequencing and liquid chromatography-mass spectrometry analysis of the secretomes of encapsulated organisms yielded detailed genotype/phenotype descriptions. This platform was probed with uHTS for biocatalysts anchored to yeast with enrichment close to the theoretically calculated limit and cell-to-cell interactions. MDE-FACS allowed the identification of human butyrylcholinesterase mutants that undergo self-reactivation after inhibition by the organophosphorus agent paraoxon. The versatility of the platform allowed the identification of bacteria, including slow-growing oral microbiota species that suppress the growth of a common pathogen, Staphylococcus aureus, and predicted which genera were associated with inhibitory activity.
169 citations
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TL;DR: It is demonstrated that BETi resistance is mediated by adaptive kinome reprogramming, where activation of compensatory pro-survival kinase networks overcomes BET protein inhibition.
169 citations
Authors
Showing all 10096 results
Name | H-index | Papers | Citations |
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Richard G. Pestell | 130 | 479 | 54210 |
Alexander Spiridonov | 126 | 1198 | 77296 |
V. Stolyarov | 119 | 238 | 79004 |
Sergei D. Odintsov | 112 | 609 | 62524 |
Hans-Uwe Simon | 96 | 461 | 51698 |
Yuri Lvov | 89 | 342 | 27397 |
Alexei A. Starobinsky | 88 | 340 | 42331 |
Yakov Kuzyakov | 87 | 667 | 37050 |
V. E. Semenov | 74 | 372 | 22577 |
John W. Weisel | 73 | 323 | 17866 |
Klaus T. Preissner | 72 | 333 | 21289 |
Alexander Tropsha | 71 | 288 | 22898 |
Roland Winter | 68 | 468 | 15193 |
Christoph Schick | 68 | 443 | 16664 |
Marat Gilfanov | 62 | 350 | 14987 |