Lenox Hill Hospital

About: Lenox Hill Hospital is a healthcare organization based out in New York, New York, United States. It is known for research contribution in the topics: Population & Medicine. The organization has 2569 authors who have published 3561 publications receiving 114326 citations.

Delusions in first-episode psychosis: Principal component analysis of twelve types of delusions and demographic and clinical correlates of resulting domains

Abstract: Although delusions represent one of the core symptoms of psychotic disorders, it is remarkable that few studies have investigated distinct delusional themes. We analyzed data from a large sample of first-episode psychosis patients (n=245) to understand relations between delusion types and demographic and clinical correlates. First, we conducted a principal component analysis (PCA) of the 12 delusion items within the Scale for the Assessment of Positive Symptoms (SAPS). Then, using the domains derived via PCA, we tested a priori hypotheses and answered exploratory research questions related to delusional content. PCA revealed five distinct components: Delusions of Influence, Grandiose/Religious Delusions, Paranoid Delusions, Negative Affect Delusions (jealousy, and sin or guilt), and Somatic Delusions. The most prevalent type of delusion was Paranoid Delusions, and such delusions were more common at older ages at onset of psychosis. The level of Delusions of Influence was correlated with the severity of hallucinations and negative symptoms. We ascertained a general relationship between different childhood adversities and delusional themes, and a specific relationship between Somatic Delusions and childhood neglect. Moreover, we found higher scores on Delusions of Influence and Negative Affect Delusions among cannabis and stimulant users. Our results support considering delusions as varied experiences with varying prevalences and correlates.

Pregnancy in peritoneal dialysis: a case report and review of adequacy and outcomes.

Abstract: A case of pregnancy in a 27-year-old woman on peritoneal dialysis is presented. The case report is a detailed description of her course including changes in her peritoneal dialysis regimen and the use of continuous cycling to maximize dialysis adequacy while addressing the patient's recurrent abdominal pain and fullness. Also described is the management of complications including hypertension, gestational diabetes, and premature rupture of membranes. The discussion reviews the diagnosis of pregnancy, factors that may relate to outcome, and a detailed comparison of pregnancy outcomes in patients on dialysis to the general population.

Splenic infarction in human babesiosis: two cases and discussion.

Abstract: We describe 2 patients with Babesia infection who presented with fever and multiple splenic infarcts. There were no other conditions present that could potentially be causes of splenic infarction. Although retinal infarction has been described rarely in patients with babesiosis, splenic infarction has not been reported previously in association with this infection in humans.

Using exercise respiratory measurements to compare methods of exercise prescription.

Abstract: Exercise heart rate (HR) ranges based on peak HR, age-predicted maximal HR and peak oxygen consumption were compared to determine which method is most likely to result in an exercise prescription within guidelines determined from exercise respiratory measurements (upper limit--ventilatory threshold; lower limit--50% peak oxygen consumption). Exercise prescriptions based on either 80% peak HR or 70% peak measured oxygen consumption were significantly more likely to be within these guidelines (p less than 0.05) than other criteria tested; there was no significant difference between these 2 methods. Recommended exercise intensity based on 85% peak HR and 80% peak oxygen uptake resulted in a large percentage of patients with a heart rate above the ventilatory threshold (46% and 54%, respectively), whereas target HR derived from 75% peak HR and 60% peak oxygen consumption resulted in many patients with a heart rate below the lower limit (38% and 42%, respectively). Exercise prescription based on predicted maximal HR was of little value, regardless of the percentage used to determine target heart rate. The best methods identified in this study yielded an exercise intensity exceeding ventilatory threshold 15 to 20% of the time. Exercise prescription based on direct assessment of the ventilatory threshold is therefore preferred.