Showing papers by "Loma Linda University published in 1979"
TL;DR: The clinical significance of inducing scratches in teeth of adolescents was discussed in the light of “normal” enamel surface appearance at various ages, wear of teeth, and remineralization.
202 citations
TL;DR: Partial or total replacement of the ureter by small intestine was performed at the University of California/Los Angeles Hospital and affiliated hospitals 94 times in 92 patients from 1954 to 1978.
169 citations
TL;DR: The present study failed to demonstrate any significant differences between the effect of ultrasonic root debridement and hand instrumentation in the treatment of 4-6 mm deep periodontal pockets.
Abstract: . A study utilizing a split-mouth design in 18 subjects and with four operators was performed in order to compare the effect of hand and ultrasonic instrumentation of periodontal pockets. Contralateral pairs of teeth with pockets of comparable depth were treated by either hand or ultrasonic instruments. Instrumentation was repeated after 4 weeks. Pocket depth, bleeding on probing and gingival fluid measurements were used for evaluation. A gradual reduction of pocket depth and number of bleeding points took place throughout the 8-week experimental period. Clinically significant differences were not observed comparing the effect of hand instruments to ultrasonics for any of the operators. The amounts of gingival fluid were similar for both methods of instrumentation at the final examination. Thus, the present study failed to demonstrate any significant differences between the effect of ultrasonic root debridement and hand instrumentation in the treatment of 4–6 mm deep periodontal pockets.
123 citations
TL;DR: A radionuclide bolus technique has been developed that documents the absence of cerebral blood flow in suspected brain death and supplements the flat EEG, and supports a clinical diagnosis of brain death in prolonged coma.
Abstract: Two isoelectric electroencephalograms obtained 24 hours apart support a clinical diagnosis of brain death in prolonged coma. Without documentation of electrocerebral silence, physicians are reluctant to discontinue vital support systems. A radionuclide bolus technique has been developed that documents the absence of cerebral blood flow in suspected brain death and supplements the flat EEG.
In a recent review of this technique, all 27 adults who had EEG activity maintained the integrity of their cerebral blood flow. This contrasts to our studies of 5 children, all of whom demonstrated persistent EEG activity but had no evidence of cerebral blood flow by either the isotope bolus technique (5 patients) or cerebral angiography (4 patients). These children (mean age, 7 months) lacked cephalic reflexes and were maintained on assisted ventilation for an average of 15 days. Multiple electroencephalographic tracings persistently demonstrated low-voltage cortical activity over this time. Despite the lack of cerebral blood flow, all patients were continued on respiratory support. At autopsy, extensive brain liquefaction necrosis was noted. In comatose children, EEG monitoring may be of limited value while cerebral blood flow measurements can provide more practical and prognostic information.
86 citations
TL;DR: The relationship between various experimental concentrations of CO2 and calcification in Bossiella orbigniana (Decaisne) was studied by measuring Ca-45 incorporation into the crystalline matrix to suggest that calcification is controlled by a biological process that may be sensitive to pH and/or to the relative bicarbonate concentration.
Abstract: The relationship between various experimental concentrations of CO2 and calcification in Bossiella orbigniana (Decaisne) was studied by measuring Ca-45 incorporation into the crystalline matrix. Air containing CO2 at partial pressures (PCO2) of 0.04 to 5.5% was bubbled through synthetic seawater in incubation vessels. The resultant pH values in the presence of plants ranged from 6.5 to 8.7. The maximum calcification rate appears to lie between 0.11 and 1.05% PCO2. The data suggest that calcification is controlled by a biological process that may be sensitive to pH and/or to the relative bicarbonate concentration. The data also suggest that a severalfold increase in CO2 over the present atmospheric level might lead to increased calcification in this marine alga.
80 citations
TL;DR: It is speculated that the spinal cord, even more than cortex, may depend for its viability on the maintenance of PO2 above a certain level, and that much of the metabolic activity following stimulation is associated with the restoration of ionic gradients.
64 citations
TL;DR: Relationships between alveolar bone resorption, osteoporosis, and adequacy of dietary calcium-phosphorus ratios were discussed, and clinical implications of recent research findings were presented.
Abstract: The effect of a calcium and vitamin D dietary supplement on postextraction alveolar bone resorption is reported. Mean alveolar bone loss for patients receiving the supplement was 36% less than that for patients receiving a placebo medication in a 1-year double-blind study of 46 immediate denture patients. Relationships between alveolar bone resorption, osteoporosis, and adequacy of dietary calcium-phosphorus ratios were discussed, and clinical implications of recent research findings were presented.
63 citations
TL;DR: Brand et al. as mentioned in this paper conducted field study of the fossil footprints in Hermit Basin, the Grand Canyon, and laboratory studies of modern amphibian and reptile foot prints on dry sand, damp sand, wet sand, and underwater sand.
62 citations
TL;DR: Etiologic considerations include the possibility that pericardial irrigation with povidone-iodine (Betadine) solution may have contributed to subsequent fibrosis.
Abstract: Although postoperative constrictive pericarditis is rare, the diagnosis should be considered when unexplained right-sided heart failure develops after cardiac surgery. Within a 6 week interval, evidence of constrictive pericarditis developed in three patients who had recently undergone myocardial revascularization. One patient presented with biventricular failure, pericardial effusion and suspected tamponade. Severe constrictive pericarditis was demonstrated at subsequent operation. An apparent postpericardiotomy syndrome preceded evidence of right heart failure in the other two patients. Etiologic considerations include the possibility that pericardial irrigation with povidone-iodine (Betadine) solution may have contributed to subsequent fibrosis.
47 citations
TL;DR: An analysis of forty-seven previously unreported cases of minor salivary gland calculi revealed that they were usually solitary, firm, freely movable, small masses, and exhibited a striking predilection for the upper lip and buccal mucosa of adults.
44 citations
TL;DR: Pressure-volume curves indicate that about one-third to one-half of the total absorption pressure of normal subcutaneous tissue results from the Donnan osmotic pressure and electrostatic repulsion effects of interstitial polysaccharides while the remainder results from some other factor such as compressed elastic forces in the tissue.
TL;DR: During a four and one-half-year period, 32 children referred for neurologic evaluation were diagnosed as having conversion hysteria, with difficulty of diagnosis most apparent in the pseudoseizure population, all of whom could readily mimic seizure activity and most of whom were receiving anticonvulsants.
TL;DR: In this article, a stable submicelle-micelle equilibrium was established in casein reconstituted casein systems with a 2:2:1 weight ratio of ±sI-:µ-:k-casein, in a system containing a 2 mM-Ca2+ and 2.5 mM-P1.
Abstract: In reconstituted casein systems, complete sub-micelles were previously observed only under extreme conditions of ionic strength, namely a NaCl concentration of 2 M or greater. However, studies with the analytical ultracentrifuge on phosphate-containing casein systems revealed that under certain conditions, a stable sub-micelle-micelle equilibrium was established. Conditions which were standard throughout were 7.5 mg/ml protein, 0.04 M-NaCl, pH 6.6 and 37 °C. The concentrations of added CaCl2 (Ca2+) and inorganic phosphate (P1) were variable. With no P1 present, Ca-sensitive caseins precipitated or formed micelles when k-casein was present, between 6 and 7 mM-Ca2+. With 10–20 mM-P1 precipitation or micelle formation began at about 4 mM-Ca2+ and was complete at about 5 mM-Ca2+. Over this interval, during micelle formation, a sub-micelle peak with s20, w of about 13 S was observed in equilibrium with the broad micelle peak. In a system containing a 2:2:1 weight ratio of ±sI-:²-:k-casein, this sub-micelle was isolated at 4 mM-Ca2+ and 2.5 mM-P1. The mol. wt was 760000 and it thus contained approximately 33 monomer caseins. The reconstituted micelle system formed in the absence of P1 was quite temperature sensitive, forming at 37 °C but disappearing upon cooling. In the presence of P1 the micelles formed at 37 °C but were stable to cooling as are natural micelles. Evidently, a combination of hydrophobic and electrostatic interactions are involved in natural micelle formation, probably with the production of salt bridges of Ca and phosphate ions between sub-micelles.
TL;DR: Twenty-five human dental periapical lesions were obtained and three of them were positive for antigen-antibody complexes, and no staining was noted in the two lesions that were histologically diagnosed as periAPical scar tissue.
TL;DR: Glycophorin and the fragments isolated from trypsinizing intact rat, dog, sheep and human red blood cells (rbc's) neutralize the hemolytic action of the Portuguese Man-of-War venom.
TL;DR: The alterations in steady state levels of phospholipid and fatty acids may contribute to the continued activity of brain cellular membranes at temperatures approaching 0°C, according to the analysis of membranes of the brain of the ground squirrel.
TL;DR: Calcitonin-containing cells in serial, 6-micrometer sections of the thyroid glands of Swiss Webster mice, at 1 day, 2 weeks, 4 weeks and 8 weeks of age, were demonstrated by an immunoperoxidase method, using antiserum to human calcitonin.
Abstract: Calcitonin-containing cells in serial, 6-micrometer sections of the thyroid glands of Swiss Webster mice, at 1 day, 2 weeks, 4 weeks and 8 weeks of age, were demonstrated by an immunoperoxidase method, using antiserum to human calcitonin. C-cell nuclei were counted in every sixth section of both left and right lobes. The average number of C-cells counted in the thyroid glands of 8-week-old animals was 18-fold, 5.5-fold and 2.5-fold greater than the number observed in 1-day, 2-week and 4-week-old animals, respectively. C-cell concentration was found to be greatest in 4-week-old mice. Mitoses of C-cells were observed in animals which were 1 day, 2 weeks and four weeks old. No mitotic figures were seen in 8-week-old animals. A few C-cells were seen in close association with neurons. The volume of the thyroid glands of 8-week-old animals was about 14-, 4- and 3-fold greater than the volume in the 1-day-old, 2-week-old and 4-week-old mice, respectively. These changes in the C-cell population during development provide a model for the study of C-cell proliferation and storage of calcitonin.
TL;DR: This research tested the hypotheses that: (1) growth line counts are consistent between specimens of different size or age, from different tidal heights, and of different taxa; and (2) multiple, independent counters obtain consistent results in line counts made on the same sample.
TL;DR: The prophage λcI ts 857 induction test appears to be a simple, quick, and sensitive method for the screening of carcinogens and is even more sensitive than the Ames Salmonella /microsome test.
TL;DR: Alveolar-like structures cultured on a gelatin sponge substrate are composed of cells resembling type II alveolar pneumonocytes that contain aryl hydrocarbon hydroxylase (AHH) as determined by fluorescent measurements of water-soluble product from the metabolism of polycyclic aromatic hydrocarbons.
TL;DR: The MEDUSA (MEdical Dose Uniformity SAmpler) as discussed by the authors is a 16-plane multi-wire proportional chamber for beam profiles, which is used for verification and tuning of the Bevalac radiotherapy beams.
Abstract: MEDUSA (MEdical Dose Uniformity SAmpler), a 16 plane multi-wire proportional chamber, has been built to accurately measure beam profiles. The large number of planes allows for reconstruction of highly detailed beam intensity structures by means of Fourier convolution reconstruction techniques. This instrument is being used for verification and tuning of the Bevalac radiotherapy beams, but has potential applications in many beam profile monitoring situations.
TL;DR: Through a retrospective study of bladder neck contracture, it was found that bladder neck resection and incision were equally effective for treatment of postoperative bladder neckcontractures.
TL;DR: Both transmission and scanning electron microscopy were used in a study of the ultrastructure of the ultimobranchial gland of the rainbow trout, which is a bilateral cystic structure in close relation to the sinus venosus and composed of two cell types which are interspersed throughout the epithelium.
TL;DR: Optimal use of the AP-120B array processor and the pipeline processing provided by using the Eclipse 200s and the Nova 3 make a marked improvement in overall throughput.
Abstract: It has been suggested that recovery of motor and sensory function in the site distal to a peripheral nerve lesion should be improved if the nerve bundles (fasciculi) are matched and individually sutured. Three parameters are proposed to provide quantitative data: the count of the nerve fibers that regenerate, the number of functional regenerated nerve fibers, and a measurement of end organ reinnervation. A thin cross section of a transected and repaired sciatic nerve of a mongrel cat is fixed, stained, photographed, and digitized through a microscope 6 months following nerve repair. The data arrays are then subjected to four basic processing routines: edge enhancing, thresholding, template matching, and peak detection. Finally, the peaks are counted and provide an estimate of the number of nerve fibers in the nerve under study. Comparing counts of nerve fibers proximal and distal to the transection site of the nerve provide data on the proportion of regeneration present at various times. The content of this paper is, to a large extent, describing the implementation of the needed image-processing algorithms for automated counting on the Multi-MiniComputer System (MMCS). Optimal use of the AP-120B array processor and the pipeline processing provided by using the Eclipse 200s and the Nova 3 make a marked improvement in overall throughput.
TL;DR: The antisera of all challenges reacted identically with active and attenuated venoms indicating that the attenuated venom was antigenically equivalent to the active venom in in vitro immunodiffusion reactions and immunogenically equivalent in vivo in its ability to elicit humoral immune responses.
TL;DR: Data from the 1977 records of a private provider of paramedic service in the city of San Bernardino were abstracted to map the geographical pattern of demand by census tract and to obtain information as to age, sex and reason for service.
TL;DR: The experiment described deals mainly with the specific staining problems encountered when using grids coated with Formvar, and significantly reduced the occurrence of artefacts by eliminating the air‐stain interface when staining thin sections of biological material.
Abstract: SUMMARY
A new technique is presented which significantly reduced the occurrence of artefacts by eliminating the air-stain interface when staining thin sections of biological material. It is designed for simultaneous treatment of large numbers of samples. The experiment described deals mainly with the specific staining problems encountered when using grids coated with Formvar.
TL;DR: The amounts of immune IgG which specifically inhibited the hemolytic, phospholipase A 2 and lethal activities of the venom were determined and related to the possible mechanisms of hemolysis and mouse lethality.