Institution
National Nuclear Energy Commission
Government•Rio de Janeiro, Brazil•
About: National Nuclear Energy Commission is a government organization based out in Rio de Janeiro, Brazil. It is known for research contribution in the topics: Dosimetry & Laser. The organization has 3816 authors who have published 4694 publications receiving 59951 citations.
Topics: Dosimetry, Laser, Neutron, Corrosion, Monte Carlo method
Papers published on a yearly basis
Papers
More filters
••
30 citations
••
TL;DR: Radiation-synthesized bovine serum albumin nanoparticles are reported as an attempt to overcome limitations of available albumin particles, as a novel route for the development of crosslinked protein nanocarriers for the administration of chemotherapic agents or radiopharmaceuticals.
30 citations
••
TL;DR: In this article, X-ray diffraction, transmission electron microscopy, cyclic voltammetry, chronoamperommetry, and performance test on direct formic acid fuel cell at 100°C.
Abstract: Pd/C-Sb2O5·SnO2 and PdAu/C-Sb2O5·SnO2 electrocatalysts with different PdAu atomic ratio (90:10, 70:30, and 50:50) were prepared by borohydride reduction method, and characterized by X-ray diffraction, transmission electron microscopy, cyclic voltammetry, chronoamperommetry, and performance test on direct formic acid fuel cell at 100 °C. X-ray diffraction showed for Pd/C-Sb2O5·SnO2 the presence of Pd face-centered cubic (fcc) system, while for PdAu/C-Sb2O5·SnO2 it showed the presence of Pd fcc phase, PdAu fcc alloys and a segregated phases fcc Pd-rich and Au-rich phases. TEM micrographs and histograms for all electrocatalysts showed that the nanoparticles where not well dispersed on the support and some agglomerates were present. The electrochemical studies showed that PdAu/C-Sb2O5·SnO2 (70:30) had superior performance for formic acid electro-oxidation at 25 °C compared to others electrocatalysts prepared while PdAu/C-Sb2O5·SnO2 (90:10) showed superior performance in direct formic acidic fuel cell at 100 °C. These results indicated that the addition of 10–30 % Au to Pd favor the electro-oxidation of formic acid. This effect could be attributed to the synergy between the constituents of the electrocatalyst (metallic Pd and Au, SnO2, and Sb2O5·SnO2).
30 citations
••
TL;DR: The results showed that the RBF networks produced slightly better results than the MLP networks, but, for practical purposes, both can be considered of similar accuracy.
30 citations
••
TL;DR: Lymphocytes from the breast cancer patients presented an initial radiosensitivity similar to that of healthy subjects but a deficient repair mechanism made them more vulnerable to the genotoxic action of ionizing radiation, and additional donors will be necessary for a more accurate evaluation.
Abstract: Genetic damage caused by ionizing radiation and repair capacity of blood lymphocytes from 3 breast cancer patients and 3 healthy donors were investigated using the comet assay. The comets were analyzed by two parameters: comet tail length and visual classification. Blood samples from the donors were irradiated in vitro with a 60Co source at a dose rate of 0.722 Gy/min, with a dose range of 0.2 to 4.0 Gy and analyzed immediately after the procedure and 3 and 24 h later. The basal level of damage and the radioinduced damage were higher in lymphocytes from breast cancer patients than in lymphocytes from healthy donors. The radioinduced damage showed that the two groups had a similar response when analyzed immediately after the irradiations. Therefore, while the healthy donors presented a considerable reduction of damage after 3 h, the patients had a higher residual damage even 24 h after exposure. The repair capacity of blood lymphocytes from the patients was slower than that of lymphocytes from healthy donors. The possible influence of age, disease stage and mutations in the BRCA1 and BRCA2 genes are discussed. Both parameters adopted proved to be sensitive and reproducible: the dose-response curves for DNA migration can be used not only for the analysis of cellular response but also for monitoring therapeutic interventions. Lymphocytes from the breast cancer patients presented an initial radiosensitivity similar to that of healthy subjects but a deficient repair mechanism made them more vulnerable to the genotoxic action of ionizing radiation. However, since lymphocytes from only 3 patients and 3 normal subjects were analyzed in the present paper, additional donors will be necessary for a more accurate evaluation.
30 citations
Authors
Showing all 3838 results
Name | H-index | Papers | Citations |
---|---|---|---|
Giorgio Parisi | 108 | 941 | 60746 |
Sergio Ferrara | 105 | 726 | 44507 |
Richard Wilson | 70 | 809 | 21477 |
Eliana B. Souto | 66 | 447 | 15706 |
Andrea Saltelli | 65 | 184 | 31540 |
Fausto Croce | 51 | 162 | 11753 |
Sílvia M. Rocha | 42 | 163 | 4934 |
Marcos Duarte | 41 | 122 | 5855 |
Luiz Gustavo Cançado | 41 | 106 | 13155 |
Ruggero Caminiti | 41 | 267 | 7296 |
Francesco Romanelli | 40 | 236 | 5756 |
Mario Molinaro | 39 | 111 | 5923 |
Giovanna Cenacchi | 38 | 217 | 4948 |
Claudio Pellegrini | 38 | 235 | 5885 |
Maria Manuela Silva | 37 | 324 | 5258 |