Institution
National Nuclear Energy Commission
Government•Rio de Janeiro, Brazil•
About: National Nuclear Energy Commission is a government organization based out in Rio de Janeiro, Brazil. It is known for research contribution in the topics: Dosimetry & Laser. The organization has 3816 authors who have published 4694 publications receiving 59951 citations.
Topics: Dosimetry, Laser, Neutron, Corrosion, Monte Carlo method
Papers published on a yearly basis
Papers
More filters
••
TL;DR: Findings suggest that native microbial communities in sites contaminated with heavy metals can be immobilized in fixed-bed bioreactors and used to treat metal contaminated water.
50 citations
••
50 citations
••
TL;DR: In this article, the effects of various geometrical parameters of the test section and of the inlet water flow rate on the onset of flooding, on the partial delivery of water and on the zero liquid penetration were investigated.
50 citations
••
TL;DR: In this article, a generalized solution of the eigenvalue problem for any numbers of layers was developed using mathematical induction, establishing recurrence formulas and a transcendental equation for determining the Eigenvalues.
50 citations
••
TL;DR: A facile and direct synthesis route is reported to obtain hybrid functional nanosystems based on silica-P(N-iPAAm) by using a neutral surfactant and without any functionalization method and the assessment of its release rate of a model drug.
Abstract: Recent studies indicate the use of mesoporous silica and polymeric sensitive hydrogels as suitable for drug delivery systems due to their specific characteristics. Polymeric hydrogels, such as poly(N-isopropylacrylamide) [P(N-iPAAm)], show volumetric expansion/contraction behaviour at 306 K, which that can be used to develop a thermosensitive drug delivery system. In this study, we report a facile and direct synthesis route to obtain hybrid functional nanosystems based on silica-P(N-iPAAm) by using a neutral surfactant and without any functionalization method and the assessment of its release rate of a model drug. The materials were characterized by Fourier transform infrared spectroscopy, nitrogen adsorption, scanning electron microscopy, transmission electron microscopy and thermal analysis. A release assay with atenolol monitored by UV–Vis spectroscopy was performed for pure SBA-15 and a hybrid system at different temperatures in order to evaluate the influence of the thermosensitive behaviour of the polymer on the release kinetics. The response of the hybrid system as a drug delivery device is influenced by the volumetric contraction of P(N-iPAAm) up to the lower critical solution temperature (LCST) due to phase transition. Above the LCST, drug release depends essentially on the temperature.
50 citations
Authors
Showing all 3838 results
Name | H-index | Papers | Citations |
---|---|---|---|
Giorgio Parisi | 108 | 941 | 60746 |
Sergio Ferrara | 105 | 726 | 44507 |
Richard Wilson | 70 | 809 | 21477 |
Eliana B. Souto | 66 | 447 | 15706 |
Andrea Saltelli | 65 | 184 | 31540 |
Fausto Croce | 51 | 162 | 11753 |
Sílvia M. Rocha | 42 | 163 | 4934 |
Marcos Duarte | 41 | 122 | 5855 |
Luiz Gustavo Cançado | 41 | 106 | 13155 |
Ruggero Caminiti | 41 | 267 | 7296 |
Francesco Romanelli | 40 | 236 | 5756 |
Mario Molinaro | 39 | 111 | 5923 |
Giovanna Cenacchi | 38 | 217 | 4948 |
Claudio Pellegrini | 38 | 235 | 5885 |
Maria Manuela Silva | 37 | 324 | 5258 |