Institution
Niigata University of Health and Welfare
Education•Niigata, Japan•
About: Niigata University of Health and Welfare is a education organization based out in Niigata, Japan. It is known for research contribution in the topics: Medicine & Isometric exercise. The organization has 523 authors who have published 996 publications receiving 10316 citations.
Papers published on a yearly basis
Papers
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TL;DR: The authors examined whether the global clinical data for bazedoxifene could be extrapolated to a Japanese population by evaluating the results of a phase 2 study in postmenopausal Japanese women with osteoporosis as compared to those of a pivotal, phase 3 study.
Abstract: This study examined whether the global clinical data for bazedoxifene could be extrapolated to a Japanese population by evaluating the results of a phase 2 study in postmenopausal Japanese women with osteoporosis as compared to those of a pivotal, phase 3 study. The efficacy of bazedoxifene 20 and 40 mg versus placebo on lumbar spine bone mineral density (BMD), bone turnover markers, lipid profile, incidence of fractures, and safety parameters was compared between the Japanese phase 2 study (N = 429) and the global phase 3 study (N = 7,492) during a 2-year period. In the primary population for assessment of bridging, differences in the mean percent change from baseline in lumbar spine BMD at 2 years relative to placebo were greater for women treated with bazedoxifene 20 and 40 mg in the phase 2 study than in the phase 3 study. BMD changes in the bazedoxifene groups were confirmed to be similar between the phase 2 study population and a subset of the phase 3 study population with similar baseline characteristics. The effects of bazedoxifene on incidence of fractures, bone turnover markers, and lipid metabolism were similar between studies. There were no major differences in safety parameters between studies. The greater improvement in lumbar spine BMD and similar results in bone turnover markers, fracture incidence, and safety profile observed with bazedoxifene in the phase 2 study compared with the phase 3 study confirmed the feasibility of extrapolating the global clinical data to a Japanese population.
3 citations
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TL;DR: Results indicated that heating treatment just after LC has analgesic effects on DOMS, which might be mediated partly through the improvement of muscle oxidative metabolisms by changes in metabolites and elevated physiological responses.
Abstract: Physiological effects of thermal therapy in the muscle and its mechanisms of analgesic effects remain unclear. The results indicated that heating, but not icing, treatment just after lengthening co...
3 citations
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20 Mar 20203 citations
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TL;DR: The results suggest the importance of the initial stages of chewing sequences in facilitating the synchronization of bilateral masseter activity patterns, which were quantitatively assessed using T50 values.
Abstract: Masseter activity patterns during chewing, which were quantitatively assessed using T50 values, were compared between the right and left sides of healthy young males. Surface electromyograms were recorded from both masseters, and each participant was asked to chew four different agar samples at his own pace across two separate sessions. The four agar samples, each possessing differing textural properties, consisted of two normal and two distinctive agar varieties. The Pearson's correlation coefficient was calculated for each pair of T50 values to evaluate the degree of synchronization of activity patterns between both masseters. A three-way analysis of variance revealed significant main effects of the 'participant' and 'experimental session' factors, but not of the 'test food'. The number of significant coefficients increased stepwise by increasing the number of chews per sequence. These results suggest the importance of the initial stages of chewing sequences in facilitating the synchronization of bilateral masseter activity patterns.
3 citations
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TL;DR: In this paper, a cross-sectional secondary data analysis of the Frailty Registry Study with outpatients aged ≥65 years who visited a frailty clinic at a geriatric hospital was conducted.
3 citations
Authors
Showing all 527 results
Name | H-index | Papers | Citations |
---|---|---|---|
Takeshi Ikeuchi | 49 | 223 | 9765 |
Hideaki E. Takahashi | 35 | 149 | 4295 |
Emi Nakamura | 30 | 93 | 5933 |
Chiho Watanabe | 29 | 133 | 2806 |
Go Omori | 27 | 77 | 1767 |
Tome Ikezoe | 26 | 88 | 2002 |
Takashi Oite | 26 | 95 | 1941 |
Kentaro Kawanaka | 24 | 59 | 2255 |
Hiroko Nishimura | 23 | 61 | 1326 |
Seiji Niimi | 23 | 144 | 1680 |
Hideaki Onishi | 22 | 166 | 1700 |
Masatoshi Nakamura | 22 | 110 | 1832 |
Yoshimitsu Takahashi | 21 | 117 | 1700 |
Hajime Kurosawa | 20 | 86 | 1483 |
Koya Yamashiro | 19 | 58 | 875 |