Shandong University

About: Shandong University is a education organization based out in Jinan, Shandong, China. It is known for research contribution in the topics: Laser & Cancer. The organization has 99070 authors who have published 99160 publications receiving 1625094 citations. The organization is also known as: Shāndōng Dàxué.

Improved measurement of electron antineutrino disappearance at Daya Bay

Abstract: With 2.5× the previously reported exposure, the Daya Bay experiment has improved the measurement of the neutrino mixing parameter sin^2 2θ_(13) = 0.089 ± 0.010(stat) ± 0.005(syst). Reactor anti-neutrinos were produced by six 2.9 GW_(th) commercial power reactors, and measured by six 20-ton target-mass detectors of identical design. A total of 234,217 anti-neutrino candidates were detected in 127 days of exposure. An anti-neutrino rate of 0.944±0.007(stat)±0.003(syst) was measured by three detectors at a flux-weighted average distance of 1648 m from the reactors, relative to two detectors at 470 m and one detector at 576 m. Detector design and depth underground limited the background to 5 ± 0.3% (far detectors) and 2 ± 0.2% (near detectors) of the candidate signals. The improved precision confirms the initial measurement of reactor anti-neutrino disappearance, and continues to be the most precise measurement of θ_(13).

MicroRNA and drug resistance.

Abstract: Chemotherapy is the preferred treatment for malignancies. However, a successful long-term use of chemotherapy is often prevented by the development of drug resistance. Many mechanisms such as gene mutation, DNA methylation and histone modification have important roles in the resistance of cancer cells to chemotherapeutic agents. Climent suggested miR-125b was involved in the development of drug resistance by microRNA (miRNA) dysregulation. miRNAs are endogenously expressed small non-coding RNAs, which are evolutionarily conserved and function as regulators of gene expression. Much effort has been exerted in analyzing the role of miRNAs in the development of drug resistance in a variety of malignancies. Several research groups have shown that the expressions of miRNAs in chemoresistant cancer cells and their parental chemosensitive ones are different. The molecular targets and mechanisms of chemosensitivity and chemoresistance are also elucidated. This article reviews the functions of miRNAs in the development of drug resistance.

Bio-gel derived nickel/carbon nanocomposites with enhanced microwave absorption

Abstract: A bio-gel derived strategy was used to construct Ni/C nanocomposites consisting of three-dimensional (3-D) carbon networks with embedded nickel nanoparticles. The amorphous carbon prevents agglomeration of the nickel nanoparticles and thus contributes to a good impedance match. The microwave absorption properties of the Ni/C nanocomposites were optimized according to percolation theory for good impedance matching. As a result, microwave absorbing coatings, which have the advantages of thin thickness (1.75 and 1.5 mm) and light weight (25 and 30 wt%), were achieved with excellent absorbing properties (90% microwave absorption) and a broad bandwidth (13.6–18 GHz and 13.2–18 GHz). The absorbing properties were mainly attributed to the dielectric relaxation processes at 2–18 GHz from the multilevel interface, porous carbon materials and nanoscale nickel nanoparticles in the Ni/C nanocomposites. It is believed that this work not only helps to elucidate the mechanism of absorption but also provides a new design paradigm for determining the optimal content of absorbers using percolation theory. The bio-gel derived strategy paves a possible way for the mass synthesis of microwave absorbers.

Solvothermal Synthesis and Characterization of Fe3O4 and γ-Fe2O3 Nanoplates

Abstract: γ-Fe2O3 nanoplates were prepared by a simple solution process and could be transformed to Fe3O4 nanoplates while keeping the size and morphology unchanged after reduction in hydrazine solution. The crystal structure and surface organic groups of the nanoplates were characterized in detail. The nanoplates exhibited good dispersibility in polar solvents except water and strong dipolar interactions, which favored the formation of one-dimensional chainlike structure. The poly(vinylpyrrolidone) molecules in this system played a key role for the growth of nanoplates, and it was supposed that the formation of nanoplates was a kinetically controlled process. The γ-Fe2O3 and Fe3O4 nanoplates with strong dipolar interactions are ferromagnetic at room temperature.