Teesside University

About: Teesside University is a education organization based out in Middlesbrough, Middlesbrough, United Kingdom. It is known for research contribution in the topics: Population & Context (language use). The organization has 2155 authors who have published 5540 publications receiving 118373 citations. The organization is also known as: University of Teesside.

Nitric oxide-mediated cutaneous microvascular function is impaired in polycystic ovary sydrome but can be improved by exercise training

Abstract: Polycystic ovary syndrome (PCOS) is associated with cardiovascular disease. The contribution of the nitric oxide (NO) dilator system to cutaneous endothelial dysfunction is currently unknown in PCOS. Our aim was to examine whether women with PCOS demonstrate impaired cutaneous microvascular NO function and whether exercise training can ameliorate any impairment. Eleven women with PCOS (age, 29 ± 7 years; body mass index, 34 ± 6 kg m(-2)) were compared with six healthy obese control women (age, 29 ± 7 years; body mass index, 34 ± 5 kg m(-2)). Six women with PCOS (30 ± 7 years; 31 ± 6 kg m(-2)) then completed 16 weeks of exercise training. Laser Doppler flowmetry, combined with intradermal microdialysis of l-N(G)-monomethyl-l-arginine, a nitric oxide antagonist, in response to incremental local heating of the forearm was assessed in women with PCOS and control women, and again in women with PCOS following exercise training. Cardiorespiratory fitness, homeostasis model assessment for insulin resistance, hormone and lipid profiles were also assessed. Differences between women with PCOS and control women and changes with exercise were analysed using Student's unpaired t tests. Differences in the contribution of NO to cutaneous blood flow [expressed as a percentage of maximal cutaneous vasodilatation (CVCmax)] were analysed using general linear models. At 42°C heating, cutaneous NO-mediated vasodilatation was attenuated by 17.5%CVCmax (95% confidence interval, 33.3, 1.7; P = 0.03) in women with PCOS vs. control women. Exercise training improved cardiorespiratory fitness by 5.0 ml kg(-1) min(-1) (95% confidence interval, 0.9, 9.2; P = 0.03) and NO-mediated cutaneous vasodilatation at 42°C heating by 19.6% CVCmax (95% confidence interval, 4.3, 34.9; P = 0.02). Cutaneous microvascular NO function is impaired in women with PCOS compared with obese matched control women but can be improved with exercise training.

Long-term soccer-specific training enhances the rate of physical development of academy soccer players independent of maturation status.

Abstract: The aim of the study was to compare 3-year changes in physical performance between junior soccer players selected for an elite academy and age-matched controls. The 3-year changes in indicators of the physical performance were quantified in 12–16-year-old Premier League Academy (n=27) and non-academy soccer players (n=18). Data were analysed with an age-group×competitive level general linear model, covariate-adjusted for initial performance level and change in maturation. Covariate adjusted mean±SD changes were greater (standardised effect size>0.7) for the academy players in terms of countermovement jump (7.3±2.6 vs. 5.4±2.5 cm), 10 m sprint (− 0.15±0.05 vs. − 0.10±0.04 s), 20 m sprint (− 0.30±0.16 s vs. − 0.15±0.13 s), agility (− 0.19±0.01 s vs. − 0.08±0.08 s), repeated sprint (− 0.60±0.26 s vs. − 0.41±2.1 s) and intermittent endurance capacity (1 128±406 vs. 315±370 m). These data indicate that a 3-year programme of training in an elite soccer academy is associated with greater changes in physical performance indicators independently from the initial performance level of the child and change in maturation over the same period of time.

Reliability of the anaerobic threshold in cardiopulmonary exercise testing of patients with abdominal aortic aneurysms

Abstract: Anaerobic threshold (AT), determined by cardiopulmonary exercise testing (CPET), is a well-documented measure of pre-operative fitness, although its reliability in patient populations is uncertain. Our aim was to assess the reliability of AT measurement in patients with abdominal aortic aneurysms. Eighteen patients were recruited. CPET was performed four times over a 6-week period. We examined shifts in the mean AT to evaluate systematic bias with random measurement error assessed using typical within-patient error and intraclass correlation coefficient (ICC, 3,1) statistics. There was no significant or clinically substantial change in mean AT across the tests (p = 0.68). The typical within-patient error expressed as a percentage coefficient of variation was 10% (95% CI, 8-13%), with an ICC of 0.74 (95% CI, 0.55-0.89). We consider the reliability of the AT to be acceptable, supporting its clinical validity and utility as an objective marker of pre-operative fitness in this population.

Nternational joint ventures, hrm and viable knowledge migration

Abstract: International joint ventures (IJVs) are an increasingly popular form of voluntary co-operation between organizations of different sizes, sectors and geographical locations to satisfy strategic purposes and manage increasingly complex business environments. However, international joint ventures may fail, and HRM plays an important role in their success or failure. From a systems perspective, IJVs offer several kinds of complexity which may contribute to the generation of conflict and failure. The paper proposes that we explore the role of HRM in IJVs through viable systems theory, especially in relation to knowledge migration and organizational learning. The theory presented distinguishes between the cognitive, organizing and behavioural domains of the IJV as a system in the analysis of the relationship between types of worldview and behaviour in IJVs. It proposes a model of viable knowledge development in IJVs and its relationship to HRM, involving knowledge migration, appreciation and action, leading to ...

A brain-computer interface to a plan-based narrative

Abstract: Interactive Narrative is a form of digital entertainment heavily based on AI techniques to support narrative generation and user interaction, significant progress arriving with the adoption of planning techniques. However, there is a lack of unified models that integrate generation, user responses and interaction. This paper addresses this by revisiting existing Interactive Narrative paradigms, granting explicit status to users' disposition towards story characters as part of narrative generation as well as adding support for new forms of interaction. We demonstrate this with a novel Brain-Computer Interface (BCI) design, incorporating empathy for a main character derived from brain signals within filmic conceptions of narrative which drives generation using planning techniques. Results from an experimental study with a fully-implemented system demonstrate the effectiveness of a EEG neurofeedback-based approach, showing that subjects can successfully modulate empathic support of a character in a medical drama. MRI analysis also shows activations in associated regions of the brain during expression of support.