Institution
University of Minho
Education•Braga, Portugal•
About: University of Minho is a education organization based out in Braga, Portugal. It is known for research contribution in the topics: Context (language use) & Population. The organization has 10585 authors who have published 34736 publications receiving 732436 citations. The organization is also known as: Universidade do Minho & UMinho.
Topics: Context (language use), Population, Computer science, Thin film, Masonry
Papers published on a yearly basis
Papers
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TL;DR: Results exclude dependence of thyroid hormone homeostasis on any major plasma carrier per se and agree with the free hormone hypothesis which states that the biologically significant fraction taken up by the tissues, is the free circulating hormone.
Abstract: Thyroid hormones are essential for normal mammalian development and for normal metabolism. Thyroxine (T4) is the principal product synthesized by the thyroid follicles, and triiodothyronine (T3), the biologically active hormone, derives mainly from tissue T4 deiodination. More than 99% of the circulating hormone is bound to plasma proteins, mainly to thyroxine-binding globulin, transthyretin and albumin in man, and to transthyretin and albumin in rodents. The role of plasma proteins in the transport of hormones to target tissues has, for a long time, been controversial. The liver and the choroid plexus are the major sites of transthyretin synthesis, tissues from which transthyretin is secreted into the blood and the cerebrospinal fluid, respectively. Transthyretin has been proposed to mediate thyroid hormone transfer into the tissues, particularly into the brain across the choroid-plexus-cerebrospinal fluid barrier. Studies in a transthyretin-null mice strain have shown conclusively that transthyretin is not indespensable for thyroid hormones' entry into the brain and other tissues, nor for the maintenance of an euthyroid status. An euthyroid status is also observed in man totally deprived of thyroxine-binding globulin and in rats without albumin. Taken together, these results exclude dependence of thyroid hormone homeostasis on any major plasma carrier per se. This evidence agrees with the free hormone hypothesis which states that the biologically significant fraction, that is taken up by the tissues, is the free circulating hormone.
134 citations
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TL;DR: In the present paper, three commercial adhesive compounds of distinct prices and properties were selected to bond concrete substrate and repairing SFRC and the performance of the adhesives was evaluated considering both the bond strength and their prices.
134 citations
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TL;DR: Laccase structural features and catalytic mechanisms focused on the polymerization of aromatic compounds are reported and a description about the most recent research on the biosynthesis of chemicals and polymers is made.
Abstract: Laccases (benzene diol: oxidoreductases, EC 1.10.3.2) are able to catalyze the oxidation of various compounds containing phenolic and aniline structures using dissolved oxygen in water. Laccase structural features and catalytic mechanisms focused on the polymerization of aromatic compounds are reported. A description about the most recent research on the biosynthesis of chemicals and polymers is made. Selected applications of this technology are considered as well as the advantages, shortcomings and future needs related with the use of laccases.
134 citations
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TL;DR: The results indicated that low concentrations of GO and GNP may be incorporated safely in PLA to improve aspects relevant for biomedical applications, such as mechanical properties.
134 citations
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TL;DR: The results obtained demonstrated that recombinant proteins containing adhesion sequences were able to significantly increase the attachment of HMEC to BC surfaces, especially the RGD sequence.
134 citations
Authors
Showing all 10921 results
Name | H-index | Papers | Citations |
---|---|---|---|
A. Gomes | 150 | 1862 | 113951 |
Kazuhiko Hara | 141 | 1956 | 107697 |
Stefano Giagu | 139 | 1651 | 101569 |
Georges Azuelos | 134 | 1294 | 90690 |
Fumihiko Ukegawa | 133 | 1492 | 94465 |
Luis M. Liz-Marzán | 132 | 616 | 61684 |
Francesco Lacava | 130 | 1042 | 79680 |
Jozsef Toth | 130 | 1151 | 86193 |
Monica Verducci | 129 | 896 | 76002 |
Andrea Messina | 128 | 939 | 75409 |
Rostislav Konoplich | 128 | 811 | 73790 |
Michel Vetterli | 128 | 901 | 76064 |
Nuno Filipe Castro | 128 | 960 | 76945 |
Hideki Okawa | 127 | 839 | 73603 |
Nazim Huseynov | 126 | 833 | 72648 |