Institution
University of Minho
Education•Braga, Portugal•
About: University of Minho is a education organization based out in Braga, Portugal. It is known for research contribution in the topics: Context (language use) & Population. The organization has 10585 authors who have published 34736 publications receiving 732436 citations. The organization is also known as: Universidade do Minho & UMinho.
Topics: Context (language use), Population, Computer science, Thin film, Masonry
Papers published on a yearly basis
Papers
More filters
••
TL;DR: It is demonstrated that the incorporation of carbon nanofibers into porous chitosan scaffolds improved the properties of cardiac tissue constructs, presumably through enhanced transmission of electrical signals between the cells.
301 citations
••
TL;DR: Although plasmacytoid DC did not produce IL-10 upon stimulation, addition of this cytokine exogenously suppressed their production of IL-12, TNF, and IFN-α, showing trans but not autocrine regulation of these cytokines by IL- 10 in plasmacies toid DC.
Abstract: We have previously reported that mouse plasmacytoid dendritic cells (DC) produce high levels of IL-12p70, whereas bone marrow-derived myeloid DC and splenic DC produce substantially lower levels of this cytokine when activated with the TLR-9 ligand CpG. We now show that in response to CpG stimulation, high levels of IL-10 are secreted by macrophages, intermediate levels by myeloid DC, but no detectable IL-10 is secreted by plasmacytoid DC. MyD88-dependent TLR signals (TLR4, 7, 9 ligation), Toll/IL-1 receptor domain-containing adaptor-dependent TLR signals (TLR3, 4 ligation) as well as non-TLR signals (CD40 ligation) induced macrophages and myeloid DC to produce IL-10 in addition to proinflammatory cytokines. IL-12p70 expression in response to CpG was suppressed by endogenous IL-10 in macrophages, in myeloid DC, and to an even greater extent in splenic CD8alpha(-) and CD8alpha(+) DC. Although plasmacytoid DC did not produce IL-10 upon stimulation, addition of this cytokine exogenously suppressed their production of IL-12, TNF, and IFN-alpha, showing trans but not autocrine regulation of these cytokines by IL-10 in plasmacytoid DC.
299 citations
••
TL;DR: In this article, the authors evaluated the efficacy of different solvents (methanol, ethanol, acetone, hexane, ethyl acetate, water, methanol:water mixtures, ethanol: water mixtures) for extracting antioxidant phenolic compounds from brewer's spent grains (BSGs).
298 citations
••
TL;DR: The results indicate that high levels of initial adherence do not necessarily lead to thick biofilm formation and the two aspects of the pathogenesis of medical device related-infection may need to be evaluated independently to ascertain the contribution of each to the virulence of S. epidermidis causing device-related infections.
298 citations
••
TL;DR: In this paper, the role of strains in the structural and electronic properties of graphene and other two-dimensional compounds is discussed. But, the influence of strains on these properties was not considered before, such as electronic transport, spin-orbit coupling, the formation of Moire patterns and optics.
298 citations
Authors
Showing all 10921 results
Name | H-index | Papers | Citations |
---|---|---|---|
A. Gomes | 150 | 1862 | 113951 |
Kazuhiko Hara | 141 | 1956 | 107697 |
Stefano Giagu | 139 | 1651 | 101569 |
Georges Azuelos | 134 | 1294 | 90690 |
Fumihiko Ukegawa | 133 | 1492 | 94465 |
Luis M. Liz-Marzán | 132 | 616 | 61684 |
Francesco Lacava | 130 | 1042 | 79680 |
Jozsef Toth | 130 | 1151 | 86193 |
Monica Verducci | 129 | 896 | 76002 |
Andrea Messina | 128 | 939 | 75409 |
Rostislav Konoplich | 128 | 811 | 73790 |
Michel Vetterli | 128 | 901 | 76064 |
Nuno Filipe Castro | 128 | 960 | 76945 |
Hideki Okawa | 127 | 839 | 73603 |
Nazim Huseynov | 126 | 833 | 72648 |