Institution
University of Saint Mary
Education•Leavenworth, Kansas, United States•
About: University of Saint Mary is a education organization based out in Leavenworth, Kansas, United States. It is known for research contribution in the topics: Population & Galaxy. The organization has 2276 authors who have published 2399 publications receiving 58990 citations. The organization is also known as: University of St. Mary & University of St Mary.
Topics: Population, Galaxy, Active galactic nucleus, Cancer, Health care
Papers published on a yearly basis
Papers
More filters
••
TL;DR: Current therapeutic knowledge is reviewed and the increasing importance of individualization of a treatment plan is recognized, which will hopefully evolve a pattern of care that leads to a decrease in morbidity for those women with early tumours and less morbid but more effective strategies for those with advanced disease.
Abstract: Vulval carcinoma is relatively rare. The disease spreads from the vulva through embolization to the locoregional lymphatic station, the inguinofemoral nodes. Prior to this event cure can be achieved, but rarely predicted with certainty. This chapter reviews current therapeutic knowledge and recognizes the increasing importance of individualization of a treatment plan. The adoption of these principles will hopefully evolve a pattern of care that leads to a decrease in morbidity for those women with early tumours and less morbid but more effective strategies for those with advanced disease.
23 citations
••
TL;DR: The experience of creating a system of response for the diverse people and diagnoses that fall into the medical DRG bundles is described and organizational factors for enabling successful implementation of bundled payments are identified.
Abstract: BACKGROUNDThe Centers for Medicare and Medicaid Services Innovation Center introduced the Bundled Payments for Care Improvement (BPCI) initiative in 2011 as 1 strategy to encourage healthcare organizations and clinicians to improve healthcare delivery for patients, both when they are in the hospital
23 citations
••
TL;DR: The phylogenetic relationships of 21 accessions suggested by sequence data from two single copy nuclear genes showed that there are two versions of the St genome in the tetraploid Elymus caninus, and it is more likely that H. bogdanii is one of the major donors of the H copy in E. caninus.
23 citations
••
TL;DR: It is demonstrated that subthalamic nucleus deep brain stimulation does not protect the nigrostriatal system against α-syn overexpression-mediated toxicity, and whether STN DBS can be protective in other models of synucleinopathy is unknown.
Abstract: Subthalamic nucleus deep brain stimulation (STN DBS) protects dopaminergic neurons of the substantia nigra pars compacta (SNpc) against 6-OHDA and MPTP. We evaluated STN DBS in a parkinsonian model that displays α-synuclein pathology using unilateral, intranigral injections of recombinant adeno-associated virus pseudotype 2/5 to overexpress wildtype human α-synuclein (rAAV2/5 α-syn). A low titer of rAAV2/5 α-syn results in progressive forelimb asymmetry, loss of striatal dopaminergic terminal density and modest loss of SNpc dopamine neurons after eight weeks, corresponding to robust human-Snca expression and no effect on rat-Snca, Th, Bdnf or Trk2. α-syn overexpression increased phosphorylation of ribosomal protein S6 (p-rpS6) in SNpc neurons, a readout of trkB activation. Rats received intranigral injections of rAAV2/5 α-syn and three weeks later received four weeks of STN DBS or electrode implantation that remained inactive. STN DBS did not protect against α-syn-mediated deficits in forelimb akinesia, striatal denervation or loss of SNpc neuron, nor did STN DBS elevate p-rpS6 levels further. ON stimulation, forelimb asymmetry was exacerbated, indicating α-syn overexpression-mediated neurotransmission deficits. These results demonstrate that STN DBS does not protect the nigrostriatal system against α-syn overexpression-mediated toxicity. Whether STN DBS can be protective in other models of synucleinopathy is unknown.
23 citations
••
TL;DR: The effectiveness of occlusion therapy for SDA was evaluated in an attempt to establish realistic treatment outcomes and found no evidence on the effectiveness of any treatment.
Abstract: Background
Stimulus deprivation amblyopia (SDA) develops due to an obstruction to the passage of light secondary to a condition such as cataract. The obstruction prevents formation of a clear image on the retina. SDA can be resistant to treatment, leading to poor visual prognosis. SDA probably constitutes less than 3% of all amblyopia cases, although precise estimates of prevalence are unknown. In developed countries, most patients present under the age of one year; in less developed parts of the world patients are likely to be older at the time of presentation. The mainstay of treatment is removal of the cataract and then occlusion of the better-seeing eye, but regimens vary, can be difficult to execute, and traditionally are believed to lead to disappointing results.
23 citations
Authors
Showing all 2277 results
Name | H-index | Papers | Citations |
---|---|---|---|
David R. Holmes | 161 | 1624 | 114187 |
Jeremy K. Nicholson | 141 | 773 | 80275 |
Shaun Purcell | 120 | 326 | 132973 |
Brad K. Gibson | 94 | 564 | 38959 |
Andrew N. Nicolaides | 90 | 572 | 30861 |
Mark D. Fleming | 81 | 433 | 36107 |
Jill Clayton-Smith | 74 | 308 | 19168 |
Alejandro A. Rabinstein | 72 | 725 | 33802 |
Philip B. Gorelick | 70 | 297 | 26424 |
Lucien C. Manchester | 67 | 113 | 18924 |
Elizabeth Murphy | 66 | 259 | 16966 |
Graeme C.M. Black | 64 | 274 | 15554 |
Raul Urrutia | 60 | 293 | 11664 |
Jane McCusker | 59 | 220 | 11538 |
Christopher J. Mathias | 58 | 278 | 16171 |