Institution
University of Tennessee
Education•Knoxville, Tennessee, United States•
About: University of Tennessee is a education organization based out in Knoxville, Tennessee, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 41976 authors who have published 87043 publications receiving 2828517 citations. The organization is also known as: UTK & UT Knoxville.
Topics: Population, Poison control, CAS Registry Number, Context (language use), Large Hadron Collider
Papers published on a yearly basis
Papers
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TL;DR: Dawn's results confirm predictions that Vesta differentiated and support its identification as the parent body of the HEDs, and present the mineralogical characterization of Vesta, revealing that this asteroid underwent a complex magmatic evolution that led to a differentiated crust and mantle.
Abstract: The Dawn spacecraft targeted 4 Vesta, believed to be a remnant intact protoplanet from the earliest epoch of solar system formation, based on analyses of howardite-eucrite-diogenite (HED) meteorites that indicate a differentiated parent body. Dawn observations reveal a giant basin at Vesta's south pole, whose excavation was sufficient to produce Vesta-family asteroids (Vestoids) and HED meteorites. The spatially resolved mineralogy of the surface reflects the composition of the HED meteorites, confirming the formation of Vesta's crust by melting of a chondritic parent body. Vesta's mass, volume, and gravitational field are consistent with a core having an average radius of 107 to 113 kilometers, indicating sufficient internal melting to segregate iron. Dawn's results confirm predictions that Vesta differentiated and support its identification as the parent body of the HEDs.
470 citations
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TL;DR: In this article, the authors use elevation information to understand community and ecosystem responses to global climate change at much larger spatial and temporal scales than is possible through conventional ecological experiments. But, their work is limited by the complexity of predicting when and why the same variable responds differently among disparate elevational gradients.
Abstract: Community structure and ecosystem processes often vary along elevational gradients. Their responses to elevation are commonly driven by changes in temperature, and many community- and ecosystem-level variables therefore frequently respond similarly to elevation across contrasting gradients. There are also many exceptions, sometimes because other factors such as precipitation can also vary with elevation. Given this complexity, our capacity to predict when and why the same variable responds differently among disparate elevational gradients is often limited. Furthermore, there is utility in using elevational gradients for understanding community and ecosystem responses to global climate change at much larger spatial and temporal scales than is possible through conventional ecological experiments. However, future studies that integrate elevational gradient approaches with experimental manipulations will provide powerful information that can improve predictions of climate change impacts within and across ecosystems.
470 citations
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TL;DR: Based on the US EPA's Models-3/CMAQ model simulation over the Beijing region, Wang et al. as mentioned in this paper estimate that about 34% of PM 2.5 on average and 35-60% of ozone during high ozone episodes at the Olympic Stadium site can be attributed to sources outside Beijing.
470 citations
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TL;DR: It is found that in chronic HCV infection, peripheral HCV-specific T cells express high levels ofPD-1 and that blockade of the PD-1/PD-L1 interaction led to an enhanced proliferative capacity.
Abstract: The majority of people infected with hepatitis C virus (HCV) fail to generate or maintain a T-cell response effective for viral clearance. Evidence from murine chronic viral infections shows that expression of the coinhibitory molecule PD-1 predicts CD8+ antiviral T-cell exhaustion and may contribute to inadequate pathogen control. To investigate whether human CD8+ T cells express PD-1 and demonstrate a dysfunctional phenotype during chronic HCV infection, peripheral and intrahepatic HCV-specific CD8+ T cells were examined. We found that in chronic HCV infection, peripheral HCV-specific T cells express high levels of PD-1 and that blockade of the PD-1/PD-L1 interaction led to an enhanced proliferative capacity. Importantly, intrahepatic HCV-specific T cells, in contrast to those in the periphery, express not only high levels of PD-1 but also decreased interleukin-7 receptor alpha (CD127), an exhausted phenotype that was HCV antigen specific and compartmentalized to the liver, the site of viral replication.
469 citations
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TL;DR: It is hypothesized that mechanical, thermal and chemical effects of ultrasonication resulted in structural changes in BSA that altered the functional properties of the macromolecule which may be attributed to the formation of an ultrasonically induced state that differs from a thermally, mechanically or solvent induced state.
469 citations
Authors
Showing all 42211 results
Name | H-index | Papers | Citations |
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Zhong Lin Wang | 245 | 2529 | 259003 |
David Miller | 203 | 2573 | 204840 |
Bradley Cox | 169 | 2150 | 156200 |
Alexander S. Szalay | 166 | 936 | 145745 |
J. E. Brau | 162 | 1949 | 157675 |
Robert Stone | 160 | 1756 | 167901 |
Robert G. Webster | 158 | 843 | 90776 |
Zhenwei Yang | 150 | 956 | 109344 |
Sevil Salur | 147 | 1470 | 106407 |
Ching-Hon Pui | 145 | 805 | 72146 |
Tim Adye | 143 | 1898 | 109010 |
Teruki Kamon | 142 | 2034 | 115633 |
Nicholas A. Peppas | 141 | 825 | 90533 |
Krzysztof Piotrzkowski | 141 | 1269 | 99607 |
Yuri Gershtein | 139 | 1558 | 104279 |