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Institution

Wishaw General Hospital

HealthcareWishaw, Scotland, United Kingdom
About: Wishaw General Hospital is a healthcare organization based out in Wishaw, Scotland, United Kingdom. It is known for research contribution in the topics: Population & Medicine. The organization has 256 authors who have published 222 publications receiving 4324 citations.


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Journal ArticleDOI
Kenneth A. McLean, James Glasbey, Aditya Borakati, T.M. Brooks  +1162 moreInstitutions (140)
TL;DR: No 30‐day survival benefit was identified for either planned or unplanned postoperative admissions to critical care within this cohort, and substantial inter‐centre variation exists in planned critical care admissions after emergency laparotomies.
Abstract: Background Patient selection for critical care admission must balance patient safety with optimal resource allocation. This study aimed to determine the relationship between critical care admission, and postoperative mortality after abdominal surgery. Methods This prespecified secondary analysis of a multicentre, prospective, observational study included consecutive patients enrolled in the DISCOVER study from UK and Republic of Ireland undergoing major gastrointestinal and liver surgery between October and December 2014. The primary outcome was 30-day mortality. Multivariate logistic regression was used to explore associations between critical care admission (planned and unplanned) and mortality, and inter-centre variation in critical care admission after emergency laparotomy. Results Of 4529 patients included, 37.8% (n=1713) underwent planned critical care admissions from theatre. Some 3.1% (n=86/2816) admitted to ward-level care subsequently underwent unplanned critical care admission. Overall 30-day mortality was 2.9% (n=133/4519), and the risk-adjusted association between 30-day mortality and critical care admission was higher in unplanned [odds ratio (OR): 8.65, 95% confidence interval (CI): 3.51–19.97) than planned admissions (OR: 2.32, 95% CI: 1.43–3.85). Some 26.7% of patients (n=1210/4529) underwent emergency laparotomies. After adjustment, 49.3% (95% CI: 46.8–51.9%, P Conclusions After risk adjustment, no 30-day survival benefit was identified for either planned or unplanned postoperative admissions to critical care within this cohort. This likely represents appropriate admission of the highest-risk patients. Planned admissions in selected, intermediate-risk patients may present a strategy to mitigate the risk of unplanned admission. Substantial inter-centre variation exists in planned critical care admissions after emergency laparotomies.

11 citations

Journal ArticleDOI
TL;DR: The technique of US-guided axillary CVC access can be undertaken successfully in ventilated intensive care patients, even in challenging circumstances, and it is suggested that it be adopted more widely in the intensive care population.
Abstract: Central venous catheter (CVC) insertion is commonly undertaken in the ICU. The use of ultrasound (US) to facilitate CVC insertion is standard and is supported by guidelines. Because the subclavian vein cannot be insonated where it underlies the clavicle, its use as a CVC site is now less common. The axillary vein, however, can be seen on US just distal to the subclavian vein and placement of a CVC at this site gives a result which is functionally indistinguishable from a subclavian CVC. We evaluated placement of US-guided axillary CVCs in mechanically ventilated intensive care patients. Data were collected for 125 consecutive US-guided axillary CVC procedures in ventilated patients in an adult intensive care setting. All lines were inserted using real-time US guidance with an out-of-plane technique. One hundred and twenty-five procedures occurred in 119 patients. Successful line placement was achieved in 117 out of 125 (94%) procedures. Complications included four procedures that required repeating due to catheter malposition and one arterial puncture. The median number of attempts per procedure was one (IQR 1 to 2). Thirty-nine (31%) patients had a body mass index of 30 or above, 43 (34%) patients had a coagulopathy and 70 (56%) patients had significant ventilator dependence (FiO2 of 0.5 or above, or positive end expiratory pressure 10 cmH20 or above). The technique of US-guided axillary CVC access can be undertaken successfully in ventilated intensive care patients, even in challenging circumstances. Taken together with existing work on the utility and safety of this technique, we suggest that it be adopted more widely in the intensive care population.

11 citations

Journal ArticleDOI
TL;DR: LP has a high diagnostic yield, eliminating the need for neurosurgical opinion or investigation in almost 90% of cases and the test is both cost and time efficient and subjects only a small number of patients to the radiation and contrast risks of angiography.
Abstract: Introduction. Acute severe headache is a common medical presentation, and a common area of diagnostic uncertainty. Subarachnoid haemorrhage (SAH) is the cause in a minority of patients and has a high rate of morbidity and mortality. Therefore, its conclusive diagnosis with computed tomography (CT) or lumbar puncture (LP) is paramount. With advancement in imaging technology, emerging evidence now suggests that LP is no longer required for a subset of patients as CT has 100% sensitivity in detecting SAH, when performed under specific conditions. Objectives. To assess the proportion of patients with conclusive CSF xanthochromia results following a negative CT scan in suspected SAH to determine the diagnostic efficacy of LP. Methods. CSF bilirubin and oxyhaemoglobin spectrophotometric absorbance data from all centres in a regional health board were identified for consecutive patients over a 6-month period. Results were stratified as conclusive (positive or negative), or inconclusive according to national guid...

10 citations

Journal ArticleDOI
TL;DR: This account of John Charnley's work is a testimony to the lifetime achievements of one man, whose hard work and dedication have brought enormous benefit to generations of patients the world over.
Abstract: For young doctors embarking on a career in medicine, the decision on which path to take is often influenced by their experiences as an undergraduate student and, in particular, by those doctors and teachers who have stimulated and encouraged them. Likewise, inspiration can be derived from studying the life and work of eminent practitioners of the past. A final year elective module provided me with the opportunity to undertake a detailed critique of an aspect of the history of medicine of my choosing, which enabled me to investigate the history of hip replacement. This opened my eyes to the prodigious contribution of Sir John Charnley in the field of orthopaedics. His commitment to the practice and advancement of medical science is indeed an inspiration. This account of John Charnley's work is a testimony to the lifetime achievements of one man, whose hard work and dedication have brought enormous benefit to generations of patients the world over.

10 citations

Journal ArticleDOI
TL;DR: Resistant mutants were more readily isolated by growth on culture plates that contained ciprofloxacin, and the resulting MIC of the resistant mutant was also more frequently increased.

10 citations


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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20231
20222
202111
20207
20199
201812