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Showing papers in "Acta Tropica in 1990"


Journal ArticleDOI
TL;DR: Simultaneous evaluation of the relative effects of control of development of anaemia in both the pre- weaner calf and its dam, on calf performance, suggested that its measurement in an animal might be feasible at an early post-weaner stage.

73 citations


Journal ArticleDOI
TL;DR: Viable hybrid parasites were produced in the laboratory and were maintained up until the F4 generation, Comparisons of egg morphology, surface structure of adult male worms and enzyme profiles have been made between experimental hybrid lines and field isolates.

59 citations


Journal ArticleDOI
TL;DR: Trypanosomes from 36 midgut infections were isolated in procyclic culture from Glossina morsitans submorsitans and G. palpalis gambiensis in The Gambia to re-emphasise the importance of differentiating infections below the subgeneric level when estimating challenge to domestic animals.

55 citations


Journal ArticleDOI
TL;DR: A mathematical model is developed that describes the population dynamics of the freshwater snail Bulinus globosus, an intermediate host of Schistosoma haematobium, and the role of density-dependent factors and the long-term persistence of the population are discussed.

54 citations


Journal ArticleDOI
TL;DR: The results showed that prolonged maintenance of T.cruzi in mice by successive passages alters the isoenzyme and k-DNA patterns of some strains and that these alterations tend to move towards zymodeme A, suggesting a selective effect of mice over these T. cruzi populations.

53 citations


Journal ArticleDOI
TL;DR: The proportion of children with fever and/or parasitaemia was not related to age, although the numbers in the febrile group appeared to increase with age, and there were many cases of drug abuse, and use of sub-curative doses prescribed by non-medically qualified staff.

51 citations


Journal ArticleDOI
TL;DR: It is shown that a single sex-linked gene model can be fitted to most recently published data for salivary gland infection rates in tsetse, and the maturation of Trypanosoma congolense infections is shown to be independent of fly sex.

47 citations


Journal ArticleDOI
TL;DR: The human promyelocytic THP-1 cell line has been found to support the growth of Leishmania parasites and should facilitate biochemical and immunological studies on amastigotes and be of use in screening anti-parasite drugs.

41 citations


Journal ArticleDOI
TL;DR: A dose of 2.5 mg of PZQ per kg would be safer and more economical in population-oriented interventions aiming at control of T. solium taeniasis in man.

39 citations


Journal ArticleDOI
TL;DR: The aim of the present study was to assess the performance of the ELISA in an endemic area of Kenya for detecting dogs with E. granulosus infection, and comparing serological data with parasitological data obtained from the dogs by necropsy.

35 citations


Journal ArticleDOI
TL;DR: Homidium bromide was used in a strategic chemoprophylactic regime to control trypanosomiasis in Boran cattle in Kenya and no infections were detected for periods of nineteen weeks and seventeen weeks respectively.

Journal ArticleDOI
TL;DR: It was concluded that microhaematuria is a valuable indicator for the diagnosis of S. haematobium in national control programmes and can be substituted for parasitological examination with advantage but sensitivity and specificity should continue to be evaluated throughout the programme.

Journal ArticleDOI
TL;DR: Results suggested that component(s) from trypanosomes generated hormonal perturbations.

Journal ArticleDOI
TL;DR: In a study to assess the status of filariasis in the Jarawa River Valley of the savanna area of Nigeria, 940 self-selected residents from 10 villages were examined between March 1984 and April 1987, overall results showed 105 (11.2%) had microfilaraemia and/or clinical signs of Filariasis.

Journal ArticleDOI
TL;DR: Alternative mechanisms for antigen synthesis, insertion into the cuticle and export from the parasite are discussed, and currently available biochemical and functional data on the surface/secreted ES glycoproteins are presented.

Journal ArticleDOI
TL;DR: These widespread clones, named Lmajor clones, are repeatedly sampled over large geographical areas and long periods of time and their medical and epidemiological characteristics deserve to be investigated with utmost priority.

Journal ArticleDOI
TL;DR: Bloodstream forms of a stock of Trypanosoma brucei evansi were propagated in vitro for more than 14 months and all organisms were dyskinetoplastic and had lost their infectivity for mice.

Journal ArticleDOI
TL;DR: It appeared that a suitable field test would be where natural infection could be effected as early in the test as possible and anaemia control measurements carried out over 6 weeks of detected parasitaemia, and PCV post-test recovery was shown to be rapid following a single trypanocidal drug treatment.

Journal ArticleDOI
TL;DR: The present work emphasizes the need for using highly specific immunodiagnostic techniques in seroepidemiology of larval cestode infections, and refugees originating from endemic areas should be regarded as potential carriers of T. solium cysticercosis.

Journal ArticleDOI
TL;DR: The infective larvae of Acanthocheilonema viteae, Nippostrongylus brasiliensis, Trichinella spiralis and Ostertagia ostertagi were found to exhibit a rapid change in lipophilicity upon exposure to conditions simulating entry into a mammalian host environment, evidence that the surface lipid layer is heterogeneous, and possibly comprises lipid domains.

Journal ArticleDOI
TL;DR: The similarities in the molecular weights of the L2 and L3 surface-associated components and the results of immunoprecipitation experiments suggest that synthesis of the molecules found at the surface of mature infective larvae begins as early as day 6 of development in the mosquito, D. immitis.


Journal ArticleDOI
TL;DR: The plasma levels of tumor necrosis factor were measured during a longitudinal survey of 84 subjects living in an endemic area of malaria and results suggest that tumor Necrosis factor could be associated with the development of resistance against malaria.

Journal ArticleDOI
TL;DR: It is proposed that the three groups of collagen polypeptides found in SDS-PAGE correspond to collagen monomers, dimers and trimers, and that the molecules in the dimeric and trimeric forms are cross-linked via non-reducible bonds.

Journal ArticleDOI
TL;DR: Administration of DEC medicated salt is simple, rapid, safe, inexpensive, efficient, and practical for filariasis control or eradication.

Journal ArticleDOI
TL;DR: The interaction in vitro between eosinophil effector cells and third and fourth stage larvae of Onchocerca volvulus was studied by electron microscopy.

Journal ArticleDOI
TL;DR: The Southern blot hybridization experiments revealed that the DNA probe pAL1 was specific for E. multilocularis and E. granulosus and was used to detect genetic variation within a set of different E. multi-ocularis isolates which had been experimentally maintained by parasite tissue transplantation.

Journal ArticleDOI
TL;DR: Levels of circulating anodic antigen (CAA) in serum were investigated after differential treatment of 160 Sudanese patients with mixed Schistosoma haematobium and S. mansoni infections and clearing of CAA from the circulation seemed to take longer in patients treated with oxamniquine.

Journal ArticleDOI
TL;DR: The development of the high level of resistance to fenbendazole in the DASP strain is related to the history of anthelmintic usage and management of sheep and goats at the university farm.

Journal ArticleDOI
TL;DR: The resistance trait in the two stocks remained stable after their cyclical development in the tsetse vectors, and the infection rates of the drug-resistant stocks of T. congolense in G. centralis, when goats were used as reservoir hosts, were as high (range, 22.3-56.3%) as of thedrug sensitive stock.