Showing papers in "American Journal of Ophthalmology in 2021"

TL;DR: Increased digital screen time, near work and limited outdoor activities were found to be associated with the onset and progression of myopia, and could potentially be aggravated during and beyond the COVID-19 pandemic outbreak period.

TL;DR: Quantitative analysis of the CC using commercially available OCTA instruments is complicated and researchers need to tailor their strategies based on the instrument, scan patterns, anatomy, and thresholding strategies to achieve accurate and reliable measurements.

TL;DR: In this article, the retinal vessel density in macular and papillary regions in post-SARS-CoV-2 pneumonia patients by means of optical coherence tomography angiography (OCTA) was investigated.

TL;DR: Both structural and functional tests should be used to monitor glaucoma, and SDOCT still has a relevant role in detecting fast progressors in advanced disease.

TL;DR: In this article, the authors used multinomial logistic regression with lasso regularization on the training set to determine a parsimonious set of criteria for each disease and to minimize misclassification rates.

TL;DR: In this article, an interventional case series was conducted to determine whether corneal cross-linking (CXL) with individualized fluence (sub400 protocol) is able to stop keratoconus (KC) progression in ultrathin corneas with 12-month follow-up.

TL;DR: The results suggested that retinal microvascular impairments might have occurred antecedent to clinically visible diabetic retinopathy and could be detected early by OCTA, however, those manifestations could be inconsistent according to the types of diabetes mellitus.

TL;DR: The concept that inhibition of ROCK signaling represents a potent tool in regenerative therapies in FECD patients through re-activation of cell proliferation and migration as well as restoration of endothelial pump and barrier function without inducing adverse phenotypic changes is supported.

TL;DR: In this article, a multimodal model was developed to automate glaucoma detection by combining multiple deep neural networks trained on macular optical coherence tomography volumes and color fundus photographs with demographic and clinical data.

TL;DR: Real-world support that DMEK is an effective treatment for FED with respect to vision restoration, inducing a small hyperopic shift with an acceptable endothelial cell loss is provided, suggesting a learning curve on a national level.

TL;DR: In this paper, a set of diagnostic criteria for panuveitides, including exudative retinal detachment with characteristic appearance on fluorescein angiogram or optical coherence tomography or panuveitis with ≥2 of 5 neurologic symptoms/signs, were evaluated.

TL;DR: The calibrated numerical model can quantify the spatial oxygen concentration related to different scenarios such as irradiance or environmental oxygen concentration and indicates an exponential decay with increasing distance to the anterior surface.

TL;DR: In this article, the authors investigated the relationship between enlargement rates (ERs) of geographic atrophy (GA) and choriocapillaris (CC) flow deficits (FDs), mean choroidal thickness (MCT), and Choroidal vascularity index (CVI) in age-related macular degeneration (AMD).

TL;DR: GoCheck Kids as checked by a family member provides a modest correlation of visual acuity compared to the chart screen and a fair correlation of visuals compared to HOTV-Amblyopia Treatment Study protocol, though a vast majority are within 1 line.

TL;DR: In this article, the authors evaluated retinal fluid volume data extracted from OCT scans by artificial intelligence algorithms in the treatment of neovascular age-related macular degeneration (NV-AMD).

TL;DR: Biosimilars hold the potential to reduce the financial burden of the highly efficacious biologic therapy in retinal pathologies, however, the off label bevacizumab may differentiate the success of biosimilars in different geographic regions.

TL;DR: In this article, the authors used multinomial logistic regression (MLR) to determine a parsimonious set of criteria that minimized the misclassification rate among the infectious posterior/panuveitides.

TL;DR: Home-monitoring of VFs is viable for some patients, and may provide clinically useful data, and many of these anomalous tests could be identified by applying machine learning techniques to recordings from the tablets’ front-facing camera.

TL;DR: Addition of tape to the superior portion of a patient’s face mask reduced bacterial dispersion during simulated intravitreal injections, and had no difference inacterial dispersion compared to wearing N95 masks.

TL;DR: In this article, an open-source, reproducible, step-by-step method was described to design sum-of-segments thick intraocular lens (IOL) calculation formulas, and to evaluate a formula built using this methodology.

TL;DR: The case in favour of performing DALK over PK for corneal pathologies with functional endothelium when possible is strengthened, as primary DALK results in less post-operative complications and lower rates of graft rejection and failure.

TL;DR: This novel questionnaire produces a reliable domain score for person-ability that does not show significant test-retest variability across repeated administration and is psychometrically validated and available for use in evaluation of patients with IRDs.

TL;DR: The COVID-19 pandemic decreased the authors' institution’s surgical volume in April 2020 to approximately 10% of the usual volume and led to a statistically significant decrease in both the age of surgeons and patients relative to the same interval in the year prior.

TL;DR: Multivariate analysis suggest that a younger donor age and higher donor endothelial cell count are associated with better long-term graft survival for optical grafts.

TL;DR: In this article, a set of criteria for sarcoidosis-associated uveitis were evaluated using multinomial logistic regression (MLR) on the training set and validated on the validation set.

TL;DR: In this article, the authors used multinomial logistic regression to determine a parsimonious set of criteria that minimized the misclassification rate among the intermediate uveitides.

TL;DR: In this article, a modified treatment ladder algorithm incorporating transcutaneous retrobulbar amphotericin B (TRAMB) for invasive fungal rhino-orbital sinusitis (IFROS) can reduce the risk of exenteration without compromising survival.

TL;DR: In this paper, a deep learning approach was developed to describe the structural phenotype of the glaucomatous ONH and can be used as a robust GLA diagnosis tool.

TL;DR: In this article, the effect of select baseline characteristics on geographic atrophy (GA) progression in eyes receiving intravitreal pegcetacoplan or sham was evaluated in a randomized, single-masked, sham-controlled trial.

TL;DR: In this article, the authors used the Vision Function Questionnaire (VFQ-25) and Ocular Surface Disease Index (OSDI) questionnaire to assess quality of life (QOL) as measured by patient-reported outcomes (PRO) within the iStent inject® pivotal trial.