Showing papers in "Biochimie in 1982"

TL;DR: A previously unsuspected wealth of evolutionarily conserved sequences and secondary structures was uncovered, and at least seven at least of the available sequences may be folded up into elaborate secondary structure models, the cores of which are nearly identical.

TL;DR: These results are suppose to illustrate the previously observed greater affinity of polymerases under template-free conditions for purine nucleotides and can be used to account for mutagenic base selection on noninstructional DNA templates.

TL;DR: Inhibitors can be valuable tools to investigate various aspects of the physiological role of glycosidases and also to detect conformational adaptability of an enzyme.

TL;DR: Homology was detected between the structural genes for the nitrogenase complex of K. pneumoniae (nifHDK genes) and the total DNA of several Azospirillum strains and the AbRI fragment, examined after infection of E. coli minicells.

TL;DR: A unified secondary structure model applicable to all 5S RNA sequences known to-date, which contains the five helices already present in the eukaryotic model, extended by additional segments that were not previously assumed to be universally present.

TL;DR: The changes occurring in tubulin heterogeneity are developmentally controlled but it seems that alpha and beta isotubulins are independently regulated: changes in alpha tubulin occur only just before birth whereas the major evolution is concerned with the appearance and accumulation of acidic beta isotUBulins throughout development.

TL;DR: In this article, the authors investigate the interaction between porphyrine and chloroquine in terms of the interaction moleculaire entre the two drugs. But, the authors do not consider the effect of the presence of other ingredients, such as hemine andhematine, on the interaction of the two agents.

TL;DR: Models for DNA-intercalation, electron-donor systems involved in drug metabolisation, and the role of oxygen in radical reactions, are discussed in the light of recent reports.

TL;DR: It is very difficult to see how the complex mechanisms involved in controlling some of these repair pathways, such as the pleiotropic SOS response in E. coli, could have been unravelled without the use of a wide range of repair deficient mutants.

TL;DR: In this article, the authors discuss the ways in which the high fidelity of DNA replication is achieved: base selection, exonucleolytic editing, and post-replicative proofreading.

TL;DR: The results suggest that 3-methylcytosine could be responsible, at least partially, for the killing and the mutagenesis observed after cell treatment by alkylating agents.

TL;DR: It would seem that selectional pressures do act in so called variable positions as well as invariable and semi-invariable positions of tRNA molecules during evolution.

TL;DR: The results suggest that at least part of the response in the Mutatest depends on the induction of an SOS function, and that most of the genotoxins are inducer of the SOS system -i.e. can lead to activation of the RecA protease.

TL;DR: The present study emphasizes that the effects of salts on protein-nucleic acid interactions do not depend only on ionic strength but also on the nature of the salt.

TL;DR: Three aspects of lexA protein's repressor function are reviewed: how it regulates genes of the SOS response, how it governs its own synthesis, and how it recognizes its operator sites.

TL;DR: Induction, monitored quantitatively by means of a sfiA::lac operon fusion, was stronger with the plasmid phage P1 than with lambda, but the kinetics were similar, showing that plasmids and non-plasmids are not fundamentally different in their ability to produce indirect induction.

TL;DR: The complete amino acid sequence of D. africanus ferredoxin I is described, which contains 4 cysteine residues represents the most simple case of one (4 Fe-4 S) cluster ferredoxins.

TL;DR: The view that a glucose-induced reduction of disulphide bridges to sulphydryl groups participates in the stimulus-secretion coupling of nutrient-induced insulin release is supported.

TL;DR: It is concluded that the changes in the distribution of the tubulin isoforms and vimentin are directly related to neurite formation.

TL;DR: This report summarizes the cloning of the uvrA, uvrB and uvrC genes of E. coli, the identification and isolation of the gene products, the regulation of the genes, and reconstitution of active UVRABC endonuclease from the individually isolated components.

TL;DR: The biochemical basis of induction is activation of the specific proteolytic activity of recA protein, which then inactivates the lexA repressor, and the development of the inducing signal in the cell is discussed.

TL;DR: Mutations at three positions in the operator for recA have been detected, cloned and sequenced and one mutant confirms the region of major groove interaction between repressor and operator to demonstrate that RecF pathway genes other than recA are under lexA control.

TL;DR: A gene (mue) or genetic elements which confer the umuC genelike function have been found on several bacterial plasmids and may imply a transposable element associated origin of those genetic materials.

TL;DR: A two-site immunoradiometric assay of Escherichia coli recA protein is described and it yields a linear response for amounts of recAprotein in the 0.1-7 ng range.

TL;DR: The general interpretation of the results leads to the conclusion that carcinogen treatment of monkey cells activates some kind of error-prone replication mode able to better replicate UV-damaged templates but leading to a higher level of mutagenesis.

TL;DR: Fluorescence studies show that the photobinding of 3-CPs gives rise to the formation of monoadducts involving the 4',5' double bond of this molecule.

TL;DR: Evidence is reviewed that the state of the SOS regulatory system is controlled by the level of RecA protease activity, and in vitro studies indicate that ATP or dATP and single-stranded polynucleotide are both required to activate the protease.