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Showing papers in "International Journal of Cardiology in 2000"


Journal ArticleDOI
TL;DR: There does not appear to be an increased risk for development of atherosclerotic coronary artery disease in anomalous coronary arteries in patients with congenital coronary anomalies, among 4,100 adult patients who underwent diagnostic coronary arteriography, and in a small subgroup of patients with coronary fistulae.

233 citations


Journal ArticleDOI
TL;DR: Investigation of hypertensive patients' self-reported reasons for adhering to or ignoring medical advice regarding antihypertensive medication found no obvious relation between reported adherence, laboratory markers of adherence and blood-pressure levels.

231 citations


Journal ArticleDOI
TL;DR: The main components which are thought to be relevant to the pathogenesis of CHF are cytokines, adhesion molecules, autoantibodies, nitric oxide, and endothelin-1, and this review will concentrate on these factors.

177 citations


Journal ArticleDOI
TL;DR: Evidence suggests that atorvastatin may also affect the atherogenic lipoprotein phenotype found in patients with combined hyperlipidemia, and Lipid-lowering agents that are capable of lowering triglyceride levels below this threshold value will cause a shift to a less dense and, therefore, less Atherogenic LDL profile.

153 citations


Journal ArticleDOI
TL;DR: The data supports previous findings that lower, rather than higher cholesterol levels are associated with poor clinical outcome in patients with chronic heart failure and suggests that the classic risk profile is not longer relevant in established heart failure.

138 citations


Journal ArticleDOI
TL;DR: Clinical classification of aortitides is rather difficult and often misleading because morphologic characterizations of these vascular disorders are frequently overlapping and therefore additional clinical and radiologic information is usually required.

130 citations


Journal ArticleDOI
TL;DR: Discontinuation of chronic aspirin therapy in stable coronary artery disease patients may lead to acute myocardial infarction within 10 days of withdrawal as a consequence of the progressive recovery of the platelet cyclooxygenase activity which exposes to a rebound effect leading to acute coronary thrombosis.

127 citations


Journal ArticleDOI
TL;DR: The PTBA with or without stent placement is a safe and effective method for relief of stenotic lesion in patients with Takayasu's arteritis.

126 citations


Journal ArticleDOI
TL;DR: Low concentrations of high-density lipoprotein cholesterol (HDL-C) have been associated with increased risk of coronary heart disease (CHD) even when the total cholesterol (TC) and triglyceride (TG) levels are not elevated, and HDL exerts a protective effect on endothelium-dependent vasodilatation in TC being relatively normal population.

116 citations


Journal ArticleDOI
TL;DR: Results reccurence of severe chest pain with ST segment demonstrated a trend for greater inhibition of platelet abnormalities, Aggrastat (Tirofiban) infusion was aggregation and shorter bleeding times in those who started with the usual regimen dose of 0.4 micg/Kg/ had received tiroFiban plus enoxaparin.

108 citations


Journal ArticleDOI
TL;DR: Of 124 patients with Takayasu arteritis studied over a period of 20 years (1979-1999), 12 female patients experienced 24 pregnancies and all patients with poor perinatal outcome had abdominal aortic involvement and a significant delay in seeking medical attention.

Journal ArticleDOI
TL;DR: Findings confirm that chronic nonrheumatic atrial fibrillation is associated with a prothrombotic state but also suggest that there is a correlation between endothelial dysfunction, coagulation factors and left atrial dimension.

Journal ArticleDOI
TL;DR: This study suggests that the proteolytic activities of MMP-9 and TIMP-l are depressed in hypertensive patients and were not significantly affected by short-term antihypertensive treatment.

Journal ArticleDOI
TL;DR: These vascular inflammatory changes are also recognized during progression of atherosclerosis and these observations strongly suggest that inflammation is a serious risk factor of Atherosclerosis.

Journal ArticleDOI
TL;DR: The results showed that the risk factors for coronary spasm differ significantly from those for atherosclerosis-based coronary stenosis in the Japanese, and smoking alone was a significant preventable risk factor for coronary artery spasm.

Journal ArticleDOI
TL;DR: The clinical profile of young patients with TA is similar to that of adults with this disease and the causes of mortality were renal failure and heart failure in one patient each.

Journal ArticleDOI
TL;DR: Stroke at CABG is due to multiple risk factors, one of which is high-grade carotid stenosis, and pathophysiology of stroke, although multifactorial, supports embolism rather than flow limitation as the primary mechanism.

Journal ArticleDOI
TL;DR: In this article, the authors defined occurrence, lesions and clinical characteristics of grown-up Congenital Heart (GUCH) patients who develop atrial flutter (AFL) and studied all GUCH patients who presented as inpatients or outpatients with documented sustained AFL between 1996 and 1998 were studied prospectively.

Journal ArticleDOI
TL;DR: The results of this study suggest a continued decline in AMI incidence in Stockholm, and a reduction in the proportion of regular smokers has probably contributed to this decline.

Journal ArticleDOI
TL;DR: Some clinical features at stroke onset may help clinicians to differentiate cerebral infarction subtypes in patients with atrial fibrillation, which is associated with a higher in-hospital mortality both in cardioembolic and atherothrombotic stroke patients.

Journal ArticleDOI
TL;DR: The purpose of this review article is to discuss the current knowledge of platelet activation, thrombin generation, fibrinolysis, and endothelial dysfunction in CHF patients, and the potential role of anticoagulants and/or antiplatelet agents in preventing these hemostatic abnormalities.

Journal ArticleDOI
TL;DR: It is concluded that, in patients with chronic heart failure, distance ambulated in the SWT predicts event-free survival at one year better than that in the 6-MT.

Journal ArticleDOI
TL;DR: FMD% was found to be rather independent of age or BMI, and the anatomical vessel size had an influence on the test results, which was more obvious in female patients.

Journal ArticleDOI
TL;DR: In this article, the role of leptin and regulators of apoptosis in cardiac cachexia was investigated in patients with congestive heart failure and showed that cachexia is a strong predictor for mortality.

Journal ArticleDOI
TL;DR: Patients with cyanotic congenital heart disease are at risk for acute renal failure, which can be prognosed by urine analysis already 24 h after surgery, and Cyanotic glomerulopathy should be known before surgery.

Journal ArticleDOI
TL;DR: In patients with severe mitral stenosis, the presence of atrial fibrillation and in the subgroup of the patients with sinus rhythm the presenceOf large left atrium (> or =40 cm(2)) and spontaneous echo contrast were associated with higher risk of clot formation in theleft atrium and might be benefited by prophylactic anticoagulation.

Journal ArticleDOI
TL;DR: The expressions of three types of NOS were differentially regulated and iNOS produced in the non-infarcted region may contribute to the progression of heart failure after myocardial infarction in rats.

Journal ArticleDOI
TL;DR: Heterogeneity in the immune insult and the resulting arterial response patterns correlate with variations in clinical disease.

Journal ArticleDOI
TL;DR: The author recommends prophylactic bypass of involved aortic arch arteries to prevent strokes and describes Takayasu's disease as an unusual arteritis that affects young females with minimal morbidity and mortality.

Journal ArticleDOI
TL;DR: It is concluded that the antero-lateral paddle position appears more effective for DC cardioversion of persistent atrial fibrillation.