Showing papers in "International Journal of Environmental Health Research in 2004"

Climatological variables and the incidence of Dengue fever in Barbados.

Abstract: A retrospective study to determine relationships between the incidence of dengue cases and climatological variables and to obtain a predictive equation was carried out for the relatively small Caribbean island of Barbados which is divided into 11 parishes. The study used the weekly dengue cases and precipitation data for the years (1995 - 2000) that occurred in the small area of a single parish. Other climatological data were obtained from the local meteorological offices. The study used primarily cross correlation analysis and found the strongest correlation with the vapour pressure at a lag of 6 weeks. A weaker correlation occurred at a lag of 7 weeks for the precipitation. The minimum temperature had its strongest correlation at a lag of 12 weeks and the maximum temperature a lag of 16 weeks. There was a negative correlation with the wind speed at a lag of 3 weeks. The predictive models showed a maximum explained variance of 35%.

Water quality deterioration: A study of household drinking water quality in rural Honduras

Abstract: There is growing awareness that drinking-water can become contaminated following its collection from communal sources such as wells and tap-stands, as well as during its storage in the home. This study evaluated the post-supply drinking-water quality in three rural Honduran communities using either a protected hand-dug well or borehole supply. Water management practices were documented as a basis for further research to improve household drinking-water quality. Membrane filtration was used to compare thermotolerant coliform levels in samples taken from community wells and household drinking-water storage containers. Over a 2-year period, water quality was examined in 43 households and detailed observation made of typical collection, storage and usage practice. Substantial water quality deterioration occurred between the points of supply and consumption. Deterioration occurred regularly and frequently, and was experienced by the majority of study households. Only source water quality appeared to be a significant factor in determining household water quality. None of the storage factors examined, i.e. covering the container, type of container, the material from which the container was made, and hours stored, made any significant difference to the stored water quality. Observation of household water management shows that there are multiple points during the collection to use sequence where pollution could occur. The commonality of water management practice would be an asset in introducing appropriate intervention measures.

Association between nutritional status and arsenicosis due to chronic arsenic exposure in Bangladesh

Abstract: The role of nutritional factors in arsenic metabolism and toxicity is not clear. Provision of certain low protein diets resulted in decreased excretion of DMA and increased tissue retention of arsenic in experimental studies. This paper reports a prevalence comparison study conducted in Bangladesh to assess the nutritional status among the chronic arsenic exposed and unexposed population. 138 exposed individuals diagnosed as arsenicosis patients were selected from three known arsenic endemic villages of Bangladesh and age, sex matched 144 unexposed subjects were randomly selected from three arsenic free villages. The mean arsenic concentration in drinking water for the exposed and unexposed population was 641.15 and 13.5 microg L(-1) respectively. Body Mass Index was found to be lower than 18.5, the cut off point for malnutrition, in 57 (41.31%) out of 138 exposed arsenicosis cases and 31 (21.53%) out of 144 unexposed individuals. The crude prevalence ratio (or risk) was 1.92 (95% CI = 1.33-2.78) for poor nutritional status among the arsenicosis cases compared to the unexposed population. The findings of this study add to the evidence that poor nutritional status may increase an individual's susceptibility to chronic arsenic toxicity, or alternatively that arsenicosis may contribute to poor nutritional status.

Environmental influences on helminthiasis and nutritional status among Pacific schoolchildren

Abstract: This paper describes a study undertaken to: (1) determine the prevalence of Ascaris lumbricoides, Trichuris trichiura and hookworm infections and nutritional status among Pacific Island school children; (2) identify factors influencing helminthiasis; (3) identify interventions to improve school health. A total of 3,683 children aged 5-12 years attending 27 primary schools in 13 Pacific Island countries were surveyed along with school environmental data. Stool samples were collected from 1996 children (54.2%) and analysed for ova and helminths. Total prevalence of helminthiasis was 32.8%. Anaemia prevalence was 12.4%. Children with helminthiasis and anaemia were found to be 8.7 times more likely to be stunted and 4.3 times more likely to be underweight than non-anaemic and non-infected children. Four significant environmental influences on helminthiasis were identified: (1) an inadequate water supply; (2); availability of a school canteen; (3) regular water/sanitation maintenance regimes; and (4) overcrowded classrooms. Helminthiasis was found to be strongly associated with anaemia, stunting and underweight and environmental influences identified. Although mass anti-helminthic drug administrations (MDA) have been taking place, reinfection is common as drug therapy alone is not enough. Programme effectiveness depends upon upgrading school environments to include an adequate water supply, controlled food preparation/provision, well-maintained water/sanitation facilities and class sizes of 30 students or less.

Using qualitative psychology to investigate HACCP implementation barriers

Abstract: Hazard Analysis Critical Control Point (HACCP) is a system of food safety management that in the last few decades has become an increasing part of national government and international strategy to reduce the prevalence of food borne disease. Yet despite wide dissemination and scientific support of its principles, successful HACCP implementation has been limited. There has been very little in-depth consideration of the reasons behind this, and qualitative psychological research examining the interplay of factors involved is almost non-existent. For this study therefore, four in-depth narrative interviews were carried out with small business owners attempting to implement HACCP. Non-prescriptive analysis of their interviews was carried out, and this revealed five key themes acting as 'barriers' to successful implementation. These were of HACCP as difficult, burdensome and unnecessary, and hindered by staff and external problems. The analysis showed furthermore the complexity of issues underpinning problems with HACCP implementation and the way in which they operate at knowledge, attitude and behavioural levels. From this, essential issues to be addressed in order for successful HACCP to be achieved are put forward.

Relationship among prevalence of patients with Itai-itai disease, prevalence of abnormal urinary findings, and cadmium concentrations in rice of individual hamlets in the Jinzu River basin, Toyama prefecture of Japan

Abstract: This study investigated the associations among prevalence of patients with Itai-itai disease, and prevalence of abnormal urinary findings and cadmium (Cd) concentrations in rice in individual hamle...

Role of motor-vehicles and trend of air borne particulate in the Great Tehran area, Iran.

Abstract: Tehran, the capital city of Iran, is one of the largest cities in the world. It extends over an area of approximately 2,300 square kilometers and has a population of more than 10 million people. The city is suffering from atmospheric pollution arising from the rapid urbanization during the last 3 to 4 decades. The city will develop towards the west to Karaj, and large volumes of traffic will be going east – west by the year 2015. With more than 2 million vehicles in Tehran, most of which are more than 20 years old, traffic is the major source of air pollution in Tehran. The city of Tehran has a significant air pollution problem and suspended particulate matter (SPM) appears to rank high on the list pollutants. The monthly average of PM-10 in Tehran is high in autumn and low in spring. Maximum average value observed in September is over 370 μg/m3; the minimum in March (102 μg/m3) and early April (65 μg/m3). The diurnal variation PM-10 concentration have been studied.

Hospital waste management status in university hospitals of the Fars province, Iran.

Abstract: Hospital waste contains large quantities of hazardous materials. In Iran, as in many developing countries, not much attention has been paid to this matter. Little information is available regarding the generation and disposal of medical waste in Iran, and this fact hinders planning for a better management of the aforementioned waste. This paper describes a survey performed on the collection and disposal of waste in the university hospitals of the Fars province, which are the medical referral centres in the southern half of the country, and the results obtained are fully discussed. The lack of separation between hazardous and non- hazardous waste, an absence of necessary rules and regulations applying to the collection of waste from the hospital wards and the on-site transport to a temporary storage location, a lack of proper waste treatment, disposal of hospital waste along with municipal garbage, insufficient training of personnel, insufficient personal protective equipment and lack of knowledge regarding the proper use of such equipment, were the main findings. For a rapid improvement of existing conditions, performing extensive research for the assessment of present situation in the hospitals of this country, compilation of rules and establishment of standards along with effective training for the personnel is recommended.

Comparison of the microbiologic quality of point-of-use (POU)-treated water and tap water.

Abstract: Activated carbon filtration devices placed on household faucets are used to improve the taste and odour of tap water. However, there has been a concern that the growth of bacteria capable of causing opportunistic infections in these devices might present a public health risk. The water quality from point-of-use (POU) water activated carbon treatment devices and that of tap water with POU-connections and tap water without POU devices were compared. Heterotrophic plate count (HPC) bacteria, total and faecal coliforms, and acid-fast organisms (Mycobacteria spp.), as well as, the opportunistic bacterial pathogens Aeromonas hydrophila, Plesiomonas shigelloides, and Pseudomonas aeruginosa were enumerated. The highest concentration of bacteria was found in POU-treated water. P. aeruginosa, acid-fast organisms, and total coliforms were present in 38.5, 43.8, and 82.4% of the samples, respectively. HPC bacteria were present in all of the POU-treated water samples, with concentrations ranging from 10(2) to 10(7) colony forming units/mL. Neither faecal coliforms nor P. shigelloides were recovered from any samples. Tap water with a POU-connection also had higher numbers of bacteria than tap water samples. It was concluded that tap water without POU devices had lower numbers of A. hydrophila, acid-fast organisms, HPC bacteria, P. aeruginosa and coliforms than POU-treated water, and tap water with a POU-connection. The use of POU-devices may amplify the numbers of bacteria present in the tapwater by promoting biofilm formation. Based on a daily ingestion of two liters of POU treated water, A. hydrophila and P. aeruginosa had a probability of less than 10(-6) of colonizing the gut; however, annual risks could be as much as 100-fold greater.

Composition of eye cosmetics (kohls) used in Cairo.

Abstract: A total of 18 kohl samples were analysed using X-ray powder diffraction (XRPD) and scanning electron microscopy (SEM). All the samples were purchased in Cairo and eleven of them originated in Egypt. The main component of six samples was found to be galena (PbS); where four of these samples originated in Egypt and two in India. For a further ten samples the main component was found to be one of the following: amorphous carbon, calcite (CaCO3), cuprite (Cu2O), goethite (FeO(OH)), elemental silicon or talc (Mg3Si4O10(OH)2). For the last two samples the main component of each was an unknown amorphous organic compound.

An assessment of food hygiene and safety at farmers' markets

Abstract: Farmers' markets are becoming a more significant part of the food-retailing sector. A survey of farmers' markets was conducted to assess aspects of food hygiene and safety. The views of the public using the markets were also examined. The range of farm products was wide and the methods utilised varied. The markets were usually temporary outdoor events with few facilities. Traders had received elementary food hygiene training and rated their hygiene standards highly. Less than half had risk management procedures in place, most did not perceive their produce as high-risk. They believed consumers to be mainly interested in food quality and to regard food safety issues highly. Consumers shopped at the markets because of the quality of the products sold. Their overall satisfaction with the markets was high and they raised no concerns about food safety. Given the restricted facilities at farmers' markets and the early phase of implementation of hygiene management systems by market traders, it may be precautionary to restrict the sale of farm products at farmers markets to those that are regarded as low-risk.

Prevalence of Giardiasis due to wastewater reuse for agriculture in the suburbs of Asmara City, Eritrea

Abstract: A study was undertaken to assess the health impact of utilization of the raw domestic sewage for vegetable cultivation in the suburbs of the capital city of Asmara, Eritrea. Standard techniques were adopted for the analysis of the samples. Results showed heavy contamination of vegetables by faecal coliforms as well as with Giardia cysts. Stool samples of 75 farmers who were occupationally exposed revealed that 45% of them were harbouring giardia cysts. The dietary intake of raw salads (lettuce, cabbage) grown on the raw sewage appear to be a causative factor of Giardiasis in the farming community as well as in the town of Tsadachristian located on the suburbs of the capital city of Asmara. The hospital data of the affected town is compared with other towns of Eritrea. The result indicates agriculture reuse of untreated wastewater is a major cause for the increase in Giardasis.

Creating a GIS application for local health care planning in Saudi Arabia.

Abstract: The purpose of this paper is to show how Geographical Information Systems can be used to support health planners on a micro-scale. The first part of this paper discusses the issue that affect local health care planning which include monitoring of catchment area and facilities management. The second part defines GIS and its possible uses in the health care field. The relevant GIS functions have also been explained. The third part of this paper discusses the created GIS application, which is made for a local health centre in Makkah City, Saudi Arabia. In this application, three sets of GIS models have been produced. These are catchment area, patient profile and patient distribution and patient flows models. The created GIS models are produced to help local health planners in their health care decision output.

Qat chewing and pesticides: a study of adverse health effects in people of the mountainous areas of Yemen.

Abstract: Chewing qat leaves, Cathula Edulis, is now a very common behaviour among the people of the mountainous areas of Yemen. For about the past 20 years, in tandem with national development, qat chewing has been rapidly expanding, and the use of chemical pesticides in qat production has been increasing. In this study, the adverse effects on human health of qat chewing combined with pesticide use were investigated. Results of interviews and questionnaires showed that chewers of qat grown with few or no chemical pesticides and chewers of qat grown with chemical pesticides have considerably different subjective symptoms. Chewers of qat produced in fields where chemical pesticides are used regularly have more symptoms than chewers of qat produced in fields where chemical pesticides are rarely or never used. Chewers of qat produced with more chemical pesticides, in particular, experience acute adverse effects on the digestive system and chronic adverse effects such as body weakness and nasal problems. Farmers who chew homemade qat on which they spread chemical pesticides by themselves may have the highest health risks regarding the combination of qat and pesticides. It is concluded that chewing qat grown with chemical pesticides causes considerable adverse health effects in human beings.

Occupational exposure to urban pollutants and plasma insulin-like growth factor 1 (IGF-1)

Abstract: The aim of present study is to evaluate whether traffic policemen exposed to urban pollutants and possible psycho-social stressors could be at risk of alterations on plasma insulin-like growth factor (IGF-1) levels compared to a control group. Out of a population of 395 Municipal Police employees, the subjects with principal confounding factors (cigarette smoking habits, drinking habits, oral contraceptives being taken, use of paints, solvents and pesticides) were excluded from the study. The remaining traffic policemen were matched with those not exposed by sex, age and length of service; 49 traffic policemen (22 men and 27 women) with outdoor activity exposed to urban pollutants and 49 not exposed subjects (22 men and 27 women) with indoor activity were included in the study. The plasma levels of IGF-1 resulted significantly higher in the male and female traffic policemen compared with control subjects (respectively P<0.001; P<0.001). The authors hypothesise that occupational exposure to chemical stressors, that may interact with possible psycho-social stressors, could cause an alteration on IGF-1 levels in traffic policemen.

Urban pollution and nickel concentration in serum.

Abstract: The study's objective has been to evaluate whether urban pollution, here nickel compounds and metallic nickel (Ni) are present, could determine serum concentrations of the above mentioned metal. Out of a population of 394 Municipal Police employees, subjects with main confounding factors were eliminated. The remaining subjects were made comparable for sex, age, and length of employment. Thus, 160 subjects were included in the study: 80 traffic policemen (42 men and 38 women) with outdoor activity exposed to urban pollutants in a direct way, and 80 administrative workers (42 men and 38 women) with indoor unexposed activity. The results obtained in the studied population demonstrate that in traffic policemen the serum levels of Ni are more elevated than those in administrative workers; both in male and female workers. The authors hypothesise that the presence of Ni as fuel additive in lead free fuels and as catalyser in catalytic exhausts, which have been obligatory in Italy in new cars for the last 10 years, could be one of the causes for the increased serum levels of the above mentioned metal in traffic policemen.

Linkages between biodiversity loss and human health: a global indicator analysis

Abstract: The association between health and biodiversity loss was explored by means of regression analysis on a global scale, with control for confounding by socio-economic developments. For this we selected indicators of human health (life expectancy, disability adjusted life expectancy, infant mortality rate and percentage low-birthweight babies), biodiversity (percentage threatened species, current forest as a percentage of original forest, percentage of land highly disturbed by man) and socio-economic development (health expenditure as percentage of GNP, percentage one-year olds immunized, illiteracy rate, GNP per capita and development grade) on a country level. After controlling for relevant socio-economic confounders, both current forest as a percentage of original forest and the percentage of land highly disturbed by human activities had no relationship with one of the health indicators. The logarithm of the percentage threatened species, showed a positive association with life expectancy and disability ad...

High levels of oxidative DNA damage in lymphocyte DNA of premenopausal breast cancer patients from Egypt.

Abstract: Egypt shows a parallel increase in premenopausal breast cancer and environmental pollution. The purpose of this study is to explore a possible relationship between oxidative DNA damage, urinary estrogen metabolites and breast cancer in Egyptian premenopausal women. We conducted a pilot study of Egyptian breast cancer involving 29 cases and 32 controls and analysed lymphocyte DNA levels of 7,8-dihydro-8-oxo-2′-deoxyguanine (8-oxo-dG), a measure of oxidative DNA damage using high performance liquid chromatography with electro-chemical detection (HPLC-ECD) method. We analysed levels of urinary estrogen metabolites, 2-hydroxyestrone (2-OHE) and 16α-hydroxyestrone (16α-OHE) by an enzyme immuno assay. We also collected residential, occupational, and reproductive histories of all study subjects. We detected, in all subjects, exceptionally high levels of 8-oxo-dG and thus oxidative DNA damage, the levels (mean 8-oxo-dG/105 dG ± SD) were significantly (P < 0.01) higher in breast cancer cases (139.4 ± 78.4) than in...

Knowledge, attitudes and behaviours related to climate change in Alberta, Canada: implications for public health policy and practice.

Abstract: Climate change has received recent extensive media attention (e.g., Kyoto Protocol) and is currently on the international public health agenda. The purpose of this study was to survey knowledge, at...

A study of environmental tobacco smoke in South Australian pubs, clubs and cafes.

Abstract: Exposure to Environmental Tobacco Smoke (ETS) in hotels and clubs is of community concern and may lead to a variety of adverse health outcomes for workers and patrons. This study sought to measure ETS in both smoking and non-smoking areas of hospitality venues in South Australia and to assess the effectiveness of ETS control measures. Seven hotels, clubs and cafes were investigated and the concentrations of airborne nicotine and particulate matter (PM(10)) were measured as markers of ETS exposure during normal to busy periods. Overall average concentrations were higher in smoking areas (nicotine = 15 microg/m(3) and PM(10) = 255microg/m(3)) compared with non-smoking dining areas (nicotine = 7 microg/m(3) and PM(10) = 192 microg/m(3)). The data demonstrate an approximate two-fold reduction of ETS within non-smoking areas and suggest that mechanical ventilation is only partially effective in preventing propagation of ETS throughout premises. Risk models suggest that ETS exposures in non-smoking areas may still represent an appreciable health risk. It is recommended that smoking be totally banned in enclosed publicly accessible areas.

Effects of mould remediation on school teachers' health.

Abstract: The follow-up study of the health of teachers (n = 56) of three mould damage schools were done with self-administered symptom questionnaire before and 1 year after the remediation of school buildings. Technical and microbiological investigations were done parallel at the same time. In the beginning of the study symptoms of allergic rhinitis, sinusitis, conjunctivitis and fatigue were high compared to normal population and 1 year after the intervention a decrease in fatigue (OR = 0.4) and headache (OR = 0.2) was observed. An association between female gender and sinusitis was found before the remediation (OR = 8.1). Age over 40 years was a risk factor for voice problems and more than 10 working years at the same school were associated with increased risk for conjunctivitis (OR = 8.5) and headache (OR = 5.4). Other exposure situations such as mould problems at home and mould exposure during leisure time also have an effect on teachers' health. Significant reduction was found in symptoms of fatigue and headache after the cessation of exposure, while respiratory symptoms need much longer time to relieve after the remediation. Age, female gender, atopy, long-term exposure time and other exposure situations might be the risk factors for prolonged symptoms among mould exposed teachers.

Developmental toxicity potential of paclobutrazol in the rat.

Abstract: Paclobutrazol is used as a fungicide and as a plant growth regulator, but there are few studies about its potential toxic effects. Experiments were conducted to determine whether this compound has ...

Assessment of waste amalgam management in dental clinics in Ramallah and al-Bireh cities in Palestine.

Abstract: The behavior of dental health personnel was examined with regard to the handling and proper disposal of wastes generated at common dental clinics, and some of the amounts of waste they produce were...

How clean is clean enough? Recent developments in response to threats posed by chemical and biological warfare agents.

Abstract: Recent terrorist events underscore the urgent need to develop a comprehensive set of health-protective cleanup standards and effective decontamination technologies for use in the restoration of civilian facilities. Accurate scientific information remains limited in the area of biological warfare agents. However, new guidelines and calculated cleanup values are emerging for initial re-entry and long-term reoccupation following use of chemical warfare agents. This article addresses airborne, soil, and surface exposures following release of G-type chemical warfare agents and VX. Cleanup goals should be tailored to the type of population that may be exposed, potential exposure times, and other scenario-specific considerations. Three different airborne concentrations are proposed for cleanup of public sector facilities. One value is recommended for initial re-entry; a more conservative value is recommended for long-term monitoring and increased public confidence; and a third, even more conservative concentration represents essentially a no-effect level for round-the-clock airborne exposure. Health-based cleanup levels are provided for contaminated residential and industrial soil. Results are presented on the outcome of a preliminary risk assessment to determine safe surface levels (e.g., walls, floors, and handrails) for cleanup after exposure to the G agents and VX. Because specific cleanup criteria for most biological warfare agents remain problematic, recommendations are made for filling the knowledge gaps.

Prevalence of Cryptosporidium parvum in private drinking water cisterns in Bani-Kenanah district, northern Jordan.

Abstract: Due to water scarcity in Jordan, the water authority only pump the water once or twice a week to the population. Thus people in rural areas, including the Bani-Kenanah district, make the most of their water resources by storing rainwater in private reservoirs for use during periods of water shortage. These reservoirs include; underground cisterns and concrete or metal tanks. The water collected in these reservoirs is at risk of contamination. During the period March – July 2002, the three types of reservoirs from 368 households were surveyed for presence of Escherichia coli and Cryptosporidium parvum, indicators of contamination. The cistern was the most contaminated reservoir with 17% (95% CI: 13,22) for E. coli (significant, P < 0.05), and 2% (95% CI: 1,4) for C. parvum. Only 1% (95% CI: 1,6) of the metal reservoirs had E. coli, while concrete reservoirs were free. No C. parvum oocysts were detected in either the concrete or metal reservoirs. Reservoirs opening at floor level and the bucket kept outside...

A pilot study of personal exposure to respirable and inhalable dust during the sanding and sawing of medium density fibreboard (MDF) and soft wood.

Abstract: A pilot study of production of respirable and inhalable dusts from sawing and sanding medium density fibreboard (MDF) and softwood in a typical cabinet-making workshop produced high but variable exposure levels at the bench and operator position. Exposure levels for the total inhalable fraction (approximately <100 microm) were 6.9-91 mg m(-3) for MDF and 2.5-45 mg m(-3) for softwood. For the respirable fraction (< 10 microm) levels were 0.4-13 mg m(-3) for MDF and 0.4-2.9 mg m(-3) for softwood. These results show significant dust loading is produced in the coarser fraction and that the material used has a significant impact on levels produced. It suggests that fuller evaluation of operator influence of fine dust production is needed and may question the common application of a single inhalable exposure standard for wood dust to all wood working scenarios.

Detection of Cryptosporidium oocysts and Giardia cysts in swimming pool filter backwash water concentrates by flocculation and immunomagnetic separation

Abstract: The purpose of the present study was to evaluate techniques for detection of Giardia cysts and Cryptosporidium oocysts in swimming pool filter backwash water. Calcium carbonate flocculation was used for water samples concentration of 1 l filter backwash water samples. Immunomagnetic separation (IMS) was used for separation of cysts and oocysts from detrital material. Cysts and oocysts were then detected using direct immunofluorescence. ColorSeed C&G was used as an internal standard. Recoveries were examined at several processing points. Highest recoveries (23% Cryptosporidium, 18% Giardia) were obtained using lower filter backwash volumes, greater IMS volumes, and addition of Tween20 to backwash samples prior to processing. The combination of CaCO3 flocculation, IMS and direct immunofluorescence was found to be an effective tool for the detection and quantification of Giardia spp. and Cryptosporidium spp. in filter backwash water samples.

Food safety knowledge and practices in ready-to-eat food establishments.

Abstract: Safe food handling in ready-to-eat food establishments is a basic element in the reduction of foodborne illness. The aim of this research was to investigate (using a questionnaire), knowledge and attitudes about food safety held by management and staff in ready-to-eat food establishments. Fieldwork was conducted in 2002 in Wellington City, New Zealand. Managers rated 'staff with good food safety knowledge' the most important aspect of ensuring safe food. Half of these managers were prepared to pay higher wages to staff holding a current food safety certificate. Although respondents considered that closure of the establishment was the most serious business consequence of a breakdown in safe food handling, less than half (49%) were prepared to pay an additional insurance premium to cover this risk. All food handling workers should be encouraged to obtain and maintain a current food safety certificate. Environmental health officers who inspect ready-to-eat food establishments play an important role in guiding and assisting owners and staff in improving food handling standards.

Determination of lead in Smilax myosotiflora herbal preparations obtained in Malaysia.

Abstract: The DCA (Drug Control Authority), Malaysia implemented the phase 3 registration of traditional medicines on 1 January 1992 with special emphasis on the quality, efficacy and safety (including the presence of heavy metals) in all pharmaceutical dosage forms of traditional medicinal preparations. As such, a total of 100 traditional medicinal preparations, containing Smilax myosotiflora, in various pharmaceutical dosage forms, which were bought in the Malaysian market, were analysed for lead content using atomic absorption spectrophotometry. Results showed that 15% of the products analysed possessed 10.23-23.05 ppm of lead, and therefore, do not comply with the quality requirement for traditional medicines in Malaysia. The quality requirement for traditional medicines in Malaysia is that they should not exceed 10 ppm of lead. Out of these 15 products, five products exhibited 10.23-23.05 ppm of lead, in fact they have already been registered with the DCA Malaysia. However, the rest of the products, which possessed 12.24-20.72 ppm of lead, have still not been registered with the DCA Malaysia. Although this study successfully showed that only 85% of the products complied with the quality requirement for traditional medicines in Malaysia pertaining to lead, they cannot, however, be assumed to be safe from lead contamination because of batch-to-batch inconsistency.

Ambient levels of benzene in Mumbai city

Abstract: An attempt has been made to determine the levels of benzene in air at different locations in Mumbai city. Levels of benzene in air have been determined by adsorbing air at a uniform flow rate on especially fabricated activated coconut charcoal cartridges followed by thermal desorption and detection on Varian GC-MS. The results show that maximum concentrations of benzene have been observed at traffic junctions and petrol pumps.