Showing papers in "International Journal of Mass Spectrometry in 2011"

TL;DR: The Predator data station is a control system for FT-ICR mass spectrometers that champions speed and experimental flexibility while simultaneously providing stability, ease of use, and the ability to integrate more advanced hardware as it becomes available.

TL;DR: In this article, a single particle laser desorption/ionization time of flight mass spectrometer capable of determining the size and chemical compositions of individual aerosol particles in real-time was presented.

TL;DR: In this article, a projected superposition approximation (PSA) is proposed to compute molecular collision cross sections measured in ion-mobility experiments, which is able to handle complex molecular shapes (concave, convex, pores, cavities, channels) as well as the range in molecular size typical to proteins.

TL;DR: The results suggest that protein binding does not affect analyte signal, and that paper spray therefore measures the total drug concentration in blood at least in this case.

TL;DR: Vibrational predissociation spectroscopy of the HOOC(CH 2 ) 10 COO − (H 2 ) 2 and − OOC( CH 2 10 CO − (COO − H 2 ) 5 cluster ions is carried out by predissociating weakly bound H 2 molecules as discussed by the authors.

TL;DR: A set of PHP scripts facilitating H/D data visualization and presentation is described, which comprises tools helping in preparation of H/ D experiments as well as tools for turning simple tables with data on H/d exchange into different ways of representation used by the HXMS community.

TL;DR: In this paper, a negative-ion electrospray ionization (ESI) Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) was used for selective ionization of acidic components of crude oils and naphthenates.

TL;DR: In this article, the identification of volatile organic compounds (VOCs) emitted from fires of biomass commonly found in the southeast and southwest U.S. were investigated with PTR-MS and PIT-MS which are capable of fast measurements of a large number of VOCs.

TL;DR: Tandem mass spectrometry of intact, noncovalently-bound protein-ligand complexes can yield structural information on the site of ligand binding and top-down proteomics for protein sequencing can be enhanced by increasing analyte charging.

TL;DR: Since the method offers high performance mass spectrometry in combination with high spatial resolution, it appears to be ideally suited for imaging peptide signatures on a cellular level with high confidence in identification and with high sensitivity.

TL;DR: Desorption electrospray ionization (DESI) was employed to measure lipids directly from sixteen bacterial samples without extraction or other sample preparation, indicating that the different species are readily distinguished and that different growth media do not prevent bacterial species differentiation in the cases examined.

TL;DR: The origins of peptide carryover in HX MS is explored, how carryover causes mass spectra to indicate false EX1 kinetics is described and an optimized washing protocol is described that can be used to eliminate peptide Carryover.

TL;DR: In this paper, the authors used a small light-weight mass spectrometer (MS) for chemical analysis of organic material directly from solution or from the solid state with potential value in future planetary missions.

TL;DR: In this paper, an ablation cell was developed to host large or several small samples (up to dimensions 230mm× 34mm × 16mm, L ǫ× Wǫǫ D ) for high spatial resolution analysis, which can have a significant impact on numerous applications, such as imaging of biological samples or trace element determinations on climate archives.

TL;DR: In this article, the effects of various concentrations of solvent vapor (either water or methanol) added to the curtain/drift gas in a planar high-field asymmetric waveform ion mobility spectrometer (FAIMS) have been examined.

TL;DR: In this article, a systematic empirical investigation of ESI(+)-MS-MS dissociation pathways of over 1000 spectra of small organic compounds, containing more than 30 chemical functional groups, was performed.

TL;DR: In this article, the authors demonstrate a new ToFAMS data acquisition mode capable of collecting high-resolution aerosol mass spectra at rates exceeding 1 kHz, which is about 1/10 of the physically meaningful limits imposed by the ToF-AMS detection processes.

TL;DR: In this article, a real-time mass spectrometry (DART-MS) was used for characterizing 16 reference papers of known manufacture in terms of their pulp composition and pitch contaminants.

TL;DR: In this paper, the authors derived an expression for the equilibrium value p e under space charge dominated conditions typical of an ES cloud (probably also of a corona discharge): p e ǫ=ǫ kǫ o /( Z s q ) This simple expression is derived from a balance between space charge dilution and the rate of ionization of neutral vapor.

TL;DR: In this paper, the authors applied hyphenated techniques (liquid chromatography and gel electrophoresis coupled to inductively coupled plasma-mass spectrometry (ICP-MS)) to the characterisation of synthesized gold nanoparticles.

TL;DR: In this paper, the authors proposed an alternative for production of multiply charged ions that is based on the recent discovery that laser ablation of certain common matrix-assisted laser desorption/ionization (MALDI) matrixes produce multiply charged ion at atmospheric pressure (AP) that are similar in charge state distribution to ions produced by electrospray ionization (ESI).

TL;DR: The quantitative determination of 48 molecular species of regioisomeric diacylglycerols has been made in a single analysis of an extract of bone marrow derived macrophages, yielding species that are sensitively and uniquely determined by constant neutral loss mass spectrometry.

TL;DR: The results indicate that glycosylation of inhibitory serpins does not interfere with either native state flexibility or the native instability that is required for efficient function, though it may confer resistance to degradation by proteases and thus extend the half-life of circulating serpins.

TL;DR: This review focuses on the methods to isolate circulating cell free DNA from body fluids, their quantitative analysis and mass spectrometry based characterization in evolving applications as prenatal and cancer diagnostic tools.

TL;DR: The results indicate that binding of positive counter ions causes a decrease in collision cross section (CCS) measurements, thus promoting a more compact octasaccharide structure.

TL;DR: In this paper, a novel surface transport technique called ion surfing is proposed which relies on a traveling potential wave combined with a static repelling RF field and the results of numerical simulations are presented and the observed features of ion surfing are discussed.

TL;DR: In this paper, a review of inductively coupled plasma mass spectrometers (ICP-MS) as a powerful analytical tool for elemental speciation analysis is presented, focusing on As, Hg, I, Se, Sb, and Sn.

TL;DR: A rapid profiling method for bovine and human milk gangliosides employing matrix-assisted desorption/ionization (MALDI) Fourier transform ion cyclotron resonance (FTICR) mass spectrometry (MS) found that only in human milk Ganglioside carbon always even numbered, which is consistent with the notion that differences in the oligosaccharide and the ceramide moieties confer to their physiological distinctions.

TL;DR: In this article, a fast screening technique for the detection of phthalic acid esters (PAEs) in poly vinyl chloride (PVC) samples was developed using Direct Analysis in Real Time (DART) ionization tandem mass spectrometry.

TL;DR: In this paper, the C-O and C-C stretching vibrational modes of 18-crown-6 ether (18c6) complexes with alkaline-earth metals (Mg(2+), Ca(2+) and Ba(2 +)) stored in the cell of a Fourier Transform Ion Cyclotron Resonance mass spectrometer were investigated.