Showing papers in "Journal of Chromatography A in 2013"

TL;DR: Deep eutectic solvents were used to extract flavonoids (myricetin and amentoflavone), which are well known and widely used antioxidants, to extend their applications and highlight their potential for the extraction and determination of a range of bioactive compounds or drugs.

TL;DR: The present work describes the development of a fast and robust analytical method for the determination of 53 antibiotic residues, covering various chemical groups and some of their metabolites, in environmental matrices that are considered important sources of antibiotic pollution, namely hospital and urban wastewaters, as well as in river waters.

TL;DR: The methodological solutions, together with properly matched sampling devices for collecting analytes from samples with varying matrix composition, enable to reduce the number of errors during the sample preparation prior to chromatographic analysis as well as to limit the negative impact of this analytical step on the natural environment and the health of laboratory employees.

TL;DR: The present review focuses on the recent advances made in DLLME; the selected papers that are discussed in this work represent modifications that fall into three main categories (exploration of new extraction Solvents, disperser solvents and combination with other techniques).

TL;DR: A liquid chromatography-tandem mass spectrometric method was described to detect tobacco-specific nitrosamines (TSNAs) in replacement liquids of electronic cigarettes and solid-phase extraction and liquid-liquid extraction were compared to each other to select the optimum clean-up method.

TL;DR: An innovative sample preparation procedure based on the quick, easy, cheap, effective, rugged and safe (QuEChERS) method was developed, and the protocol was successfully applied to various types of sludge collected in several sewage works in France.

TL;DR: Comparison study shows that the recoveries of target PAHs are low when they are extracted using traditional SPE method even with the addition of methanol or tetrabutylammonium bromide surfactants in water samples, suggesting great application potential of magnetic SPe method to preconcentrate highly hydrophobic contaminants (such as PAhs) from large volume of water samples.

TL;DR: In this review, the recent applications of different nanomaterials, including metallic nanoparticles, metal organic frameworks (MOFs) materials, carbonaceous nanommaterials and siliceous nanoparticle, in sample preparation techniques are discussed.

TL;DR: Zeolite imidazolate framework-8 (ZIF-8) was used as the novel sorbent for on-line solid-phase extraction coupled with high-performance liquid chromatography (HPLC) for the determination of oxytetracycline (OTC), tetracyCline (TC) and chlorotetracy Cline (CTC) in water and milk samples.

TL;DR: A novel approach to simultaneously perform targeted and non-targeted metabolomics as well as lipidomics from one small piece of liver or muscle tissue by ultra-high performance liquid chromatography/mass spectrometry (UHPLC/MS) following a methyl tert-butyl ether (MTBE)-based extraction.

TL;DR: Several extraction methods were evaluated in terms of recoveries and extraction precision for 113 pesticides in avocado: QuEChERS with various d-SPE clean-ups (Z-Sep, Z-Sep+, PSA+C18 and silica), miniLuke and ethyl acetate, and validated in two matrices - avocado and almonds.

TL;DR: The results demonstrated that the Fe3O4@MOF core-shell magnetic microspheres are promising sorbents in the MSPE of aromatic pollutants from environmental water samples.

TL;DR: This work reviews the current state-of-the-art of liquid chromatography coupled to high-resolution mass spectrometry (LC-HRMS) techniques applied to the analysis of pesticides in fruit-based and vegetable-based matrices and includes HRMS technology as a reliable complementary alternative allowing theAnalysis of a wide range of pesticide in food.

TL;DR: The present review addresses the use of the improved liquid chromatography (LC), ultra-high performance LC (UHPLC), coupled to MS or tandem MS (MS/MS) as the detector system for the determination of phenolic compounds in food samples.

TL;DR: In this paper, a new sensitive method based on pressurized liquid extraction (PLE) and purification by gel permeation chromatography (GPC) prior to ultra-highperformance liquid chromatography coupled to tandem mass spectrometry (UHPLC-MS/MS) was developed for the determination in fish homogenate, liver and muscle of twenty pharmaceuticals compounds and metabolites from seven commonly used therapeutic families.

TL;DR: An evaluation of HPLC-based analytical tools for the simultaneous analysis of native and oxidized cello-oligosaccharides, which are products of enzymatic cellulose degradation, found HPAEC with pulsed amperometric detection (PAD) was superior for analysis of oxidized oligosac charides, combining the best separation with superior sensitivity.

TL;DR: The magnetic molecularly imprinted polymers for resveratrol were prepared by using surface molecular imprinting technique with a super paramagnetic core-shell nanoparticle as a supporter and showed high adsorption capacity for res veratrol and contained homogeneous binding sites.

TL;DR: LC is a powerful analytical tool in the study of complex sample matrices and a further development and configuration employing Ultra-High Pressure Liquid Chromatography (UHPLC) is optimized to provide the largest known liquid chromatographic resolution and peak capacity.

TL;DR: The central role chromatographic methods, together with liquid-liquid partition coefficients, occupy in the determination of the six descriptors used in the solvation parameter model is detailed.

TL;DR: The result indicates that infants who are fed with breast milk from the milk banks are not at risk from aflatoxin and ochratoxin exposure.

TL;DR: TheMethod which gave the best results was the microwave hydrodiffusion and gravity (MHG) method which gave reduced extraction time and gave no differences in essential oil yield and sensorial perception.

TL;DR: A critical overview of the opportunities, strengths and limitations of some of the newest analytical approaches is provided, with a particular attention to liquid phase separation techniques coupled to high accuracy, high resolution mass spectrometry.

TL;DR: The UHPLC-MS/MS platform has successfully been employed over the last decade for various types of applications, including those related to bioanalysis, drug metabolism, multi-residue screening, metabolomics, biopharmaceuticals and polar compounds.

TL;DR: A reliable and rapid method for the determination of multiple mycotoxins was developed using a QuEChERS (quick, easy, cheap, effective, rugged and safe) based extraction procedure in highly pigmented and complex spice matrices, namely red chilli, black and white pepper.

TL;DR: This overview regards some critical issues in performing flow field-flow fractionation (flow FFF, FlFFF, AF4, HF-Fl FFF, HF5) and good fractogram practice (GFP) is suggested.

TL;DR: A new analytical method was developed for the determination of dialkyl and diaryl phosphates (DAPs), which are metabolites of organophosphate triesters (PFRs), in human urine and DPHP was the major DAP metabolite.

TL;DR: The developed and validation of the first fully automated method, based on on-line solid phase extraction-liquid chromatography-tandem mass spectrometry (on line-SPE-LC-MS/MS), for the determination of UV filters and transformation products, with a wide range of physicochemical properties is described.

TL;DR: An integrated experimental and modelling approach to evaluate the potential of semi-continuous chromatography for the capture of monoclonal antibodies (mAb) in clinical and commercial manufacture found that PCC capture chromatography would offer more significant savings in direct costs for early-stage clinical manufacture (proof-of-concept) than for late-stageclinical or commercial manufacture.

TL;DR: A novel low-density solvent-based vortex-assisted surfactant-enhanced-emulsification liquid-liquid microextraction was developed for the fast, simple and efficient determination of six phthalate esters in bottled water samples followed by gas chromatography-mass spectrometry (GC-MS).

TL;DR: This work thoroughly investigated different solid phase extraction mechanisms (ion pair, ion exchange, reversed phase), sorbents and derivatisation agents to enable trace-level analysis of 5-FU based on GC-MS/MS in natural and wastewaters and concluded that alkylation was rejected in favour of silylation with MTBSTFA.