Showing papers in "Journal of Heterocyclic Chemistry in 1986"

TL;DR: In this paper, a synthese sur les acyclonucleosides derives de purine ou de pyrimidine and les acYclo-C-nucleoside.

TL;DR: In this article, the antimicrobial activities of the above compounds were screened against different strains of bacteria and fungi, and the results showed that they were effective against different species of fungi.

TL;DR: In this article, a series of 2-arylthiocarbamoylhydrazino-5-phenyl-1,3,4-thiadiazoles III-VII was synthesized and cyclodesulfurized into the corresponding 3-arylamino-6phenyls-triazolo[3, 4-b][1, 3,4]thiadiadiazole VIII-XII with DCCD.

TL;DR: A number of N-substituted-1,8-naphthalimides have been prepared and their fluorescence yields measured in water at pH 7.4 as mentioned in this paper.

TL;DR: A series of macrocyclic polyether polyether (crown) ligands containing the proton-ionizable s-triazole subcyclic unit were prepared by reacting the 1-THP blocked 3,5-bis(chloromethyl)-1H-1,2,4-Triazole with various oligoethylene glycols.

TL;DR: In this paper, the correct isomeric and tautomeric structure of different 1- and 2-R1-3-R2,R3-amino-5amino,1,2,4-triazole derivatives prepared from the corresponding N-cyano-N'-R2 and R3-S-methyl-isothioureas and corresponding hydrazines was proved with the help of their ir, uv, 1H-nmr and 13C-nr spectra as well as the uv spectra of

TL;DR: In this article, the pyridinyl groups at the 5,6,7 and 8 positions were synthesized for the synthesis of 1,2,4-triazolo[4,3-a]pyridines.

TL;DR: In this paper, the Claisen-Schmidt condensation (potassium hydroxide/ethanol) of aromatic aldehydes with 3-hydroxy-3-methyl-2-butanone to give enones is described.

TL;DR: In this paper, the metalation chemistry of several 1-substituted 1H-1,2,4-triazoles has been investigated, including 1-trityl, 1-methyl, and 1-benzyl-5-lithio-1.2, 4.4-ttriazol 5-yl phosphonates.

TL;DR: The Gewald syntheses were employed to prepare a series of 2-amino-3-carboethoxythiophenes, and the syntheses of two of these, namely, the 3,4-trimethylene (1f) and 3, 4-tetramethylene derivatives, were examined in detail.

TL;DR: A series of dimethoxy[1]benzothieno[2,3-c]quinolines have been prepared by photocyclization of the appropriate N-phenyl-3-chlorobenzo[b]thiophene-2-carboxamides.

TL;DR: In this paper, 3-amino-5-methyl-(or 5-phenyl)thiophene-2-carbonitriles 7 and 8 were obtained in a single step by conjugate addition of mercaptoacetonitrile (generated in situ) to substituted acetylenic nitriles 4 and 5 and annelation of intermediate vinylic thioethers.

TL;DR: A series of new 1-(2,4-dichlorobenzoyl) hydrazones and 2-aryl/aralkyl-5-2, 4-D-Dichlorophenyl-1, 3-4-oxadiazoles have been synthesized from different aldehydes as mentioned in this paper.

TL;DR: In this paper, a new process suitable for large scale synthesis of the antitumor-antiviral agent, 2-β-D-ribofuranosyl-4-selenazolecarboxamide, has been developed.

TL;DR: In this paper, a general procedure for the preparation of aminocoumarins and aminohydroxycoumarin under mild conditions is described, and the synthesis of 3-salicylideneaminoc-marin (XIII) is described.

TL;DR: In this article, a novel synthesis of the title compounds by the facile cyclization between 2,3dichloro-5,6-dicyanopyrazine and various 2-aminopyridines under relatively mild conditions is described.

TL;DR: In this article, three new proton-ionizable macrocyclic polyether ligands containing the 4-pyridone subcyclic group have been prepared and two of these ligands contain lipophilic n-octyl substituents, while the other ligand contains a phenyl substitution.

TL;DR: Synthese de 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, and 3n-crowns-n (n=8, 9, 10) ayant carboxy-2' decyl-4' phenoxymethyl (tous ces composes sont prepares par l'intermediaire des crowns correspondants hydroxymethyles) as mentioned in this paper.

TL;DR: The reaction of 3-(2,4-dichlorophenyl)-5-mercapto with α-haloketones and 1,2-dibromoethane leading to the formation of fused heterocycles was carried out and the orientation of cyclization was studied as mentioned in this paper.

TL;DR: The direction of cyclisation of 4.4-Quinazolinones has been proved by the unambiguous synthesis of their ethylation products as discussed by the authors, and it has been shown that they can be cyclised to [1,2,4]triazoloquinazolinens and to imidazoquinazolins.

TL;DR: In this paper, the synthesis of six-membered heterocyclic rings containing two heteroatoms was performed using the 13C nmr spectroscopy to assign the structure of the synthesized compounds.

TL;DR: In this article, a general discussion of the benzoin condensation catalysis within the framework of nucleophilic carbene chemistry is carried out and as a result of it the important role played by the "dimers" is emphasized.

TL;DR: The reaction of acyl chlorides with cyclic five-membered β-enaminoesters gave exclusively N-acylated products, while reaction of cyclic seven-meganoesters gave only C-acylation products as mentioned in this paper.

TL;DR: In this paper, the synthesis and chemical properties of some 2 and 3-substituted furo[2,3-b]pyridines were described, and a 2-methyl derivative was obtained by reduction, O-acetylation and subsequent pyrolysis.

TL;DR: Aryl aldehydes I reacted with α-tetralone to give the corresponding 2-arylidene-1-tetrone II and 2-benz[g]indazole derivatives III, and the structure of all products was elucidated by chemical and spectroscopic methods.

TL;DR: Amino-3-trifluoromethylisoxazole- and -pyrazole-4-carboxylic acids were prepared by the reactions of trifluoroacetonitrile oxide or -imines with cyanoacetic acid derivatives, respectively as mentioned in this paper.

TL;DR: The synthesis of praziquantel (1), a potent anthelmintic agent, was reported in this article, which requires five steps and proceeds in 16% yield, achieving a state-of-the-art performance.

TL;DR: In this article, a number of new tetracyclic furocoumarin derivatives with a linear structure or with various angular arrangements were synthetized and characterized for having an additional cyclohexene or phenyl ring condensed at the 4′,5′ double bond of the furan ring of the furocarin nucleus, where methyl groups were introduced into positions which look most promising for enhancement of the photoreactivity of the compounds toward DNA.

TL;DR: In this article, cyclization of benzylsulphonamides with aldehydes in strong acid media is a synthetically useful route to 3,4-dihydro-1H-2,3-benzothiazine 2,2-dioxides III.

TL;DR: In this article, a mechanism for the synthesis of 3-substituted 5-aminopyrimidino[4,5-b]-[1,5]benzodiazepin-2(3H,11H)-ones was proposed.