Showing papers in "Journal of Laboratory and Clinical Medicine in 2006"

TL;DR: It is hypothesized that blood cells can act as sentinels of disease and that they could capitalize on this property of blood for the diagnosis/prognosis of disease (the "Sentinel Principle").

TL;DR: The role of HBx in the life cycle of HBV as well as the various signal transduction pathways involved in the pathogenesis ofHBV-induced hepatocarcinogenesis are examined.

TL;DR: The available scientific evidence for the use of herbs or natural substances as a complementary treatment for patients with CKD is reviewed and the literature on herbs that have been reported to cause kidney failure is reported.

TL;DR: The results of this study suggest that the lowering of elevated levels of plasma Trx-1 in cancer patients may provide a surrogate for the inhibition of tumor TrX-1 by PX-12, and Px-12 decreases plasma VEGF levels that may contribute to the antitumor activity of P X-12.

TL;DR: The results establish a protein standard in RLS, provide a comparative analysis of protein-controlled versus volumetric immunoblot techniques, and argue for a profound loss of iron storage capacity in the brain inRLS, specifically in the early onset RLS phenotype.

TL;DR: Examples show how meta-analysis has clarified thinking about the off-label use of selective serotonin reuptake inhibitors for treating child and adolescent depression, use of low-tidal volume respirator assistance for acute lung injury and acute respiratory distress syndrome patients, and the long-term use of COX-2 inhibitors for relieving arthritic pain.

TL;DR: This review focuses on proatherogenic properties of Amadori-modified serum proteins, which are perhaps underappreciated contributors to atherosclerosis in diabetes.

TL;DR: It is concluded that the ACE2 A/G polymorphism is associated with hypertension in patients with metabolic syndrome and females who carry the GG genotype had a significantly higher diastolic blood pressure compared with other genotypes.

TL;DR: The authors found that reduced NK cell numbers, probably a result of apoptotic death, may contribute to impaired NK cell activity in patients with primary Sjögren's syndrome.

TL;DR: The authors evaluated the correlation of post-cardiopulmonary bypass surgery bleeding with platelet function tests using glass bead adhesion and Thrombelastograph Platelet Mapping, finding that bleeding could be explained for 11 patients by BMI plus surgery parameters along with coagulation and/or platelet dysfunction.

TL;DR: Pseudohyperkalemia is mainly present in patients with thrombocytosis or mixed-type disorders, probably as a result of the degranulation of platelets, which offers a potassium load to the surrounding plasma at the time of clot formation in vitro.

TL;DR: The studies indicate that podocyte expression of alpha3- and beta1-integrin subunits is significantly reduced in humans with primary FSGS and chronic PAN-treated rats, before the morphological changes of FSGS are observed.

TL;DR: It is concluded that gene expression patterns may be useful in helping to further classify subtypes of renal cell carcinoma that may have clinical significance and may represent useful targets for therapy.

TL;DR: The data indicate dose-related responses in red blood indices upon chronic ethanol consumption, which may also be reflected in reference intervals for hematological parameters in health care.

TL;DR: Long-term storage of blood at 4°C does have a detrimental effect on DNA yield, but this effect seemed less significant than the age of a person, and storage ofBlood at 4 °C offers an acceptable alternative to frozen storage.

TL;DR: The existence of albumin peptides in IPK urine is demonstrated and it is suggested that receptor-mediated endocytosis plays a role in urinary albumin degradation.

TL;DR: MLPA can be considered a quick, sensitive, cost-effective, and easy method to screen for subtelomeric rearrangements, but any finding based in the testing of one probe should be confirmed by other sources.

TL;DR: The polymorphisms of p53 and p21 were significantly associated with the occurrence of smoking-related COPD in Taiwan Chinese patients, and the degree of association observed was quantitatively assessed.

TL;DR: A novel method for rapid determination of the three major FAEEs found in human plasma is described, which is precise, accurate, sensitive, and specific and deserves broader application.

TL;DR: Low-plasma VWF associated with a normal platelet VWF content may be a first useful indicator for identifying type Vicenza VWD patients.

TL;DR: The Figge-Fencl-Waston model of human plasma was applied to laboratory values obtained from two novel populations, patients with nephrotic syndrome and patients with diabetic ketoacidosis, justifying the common clinical practice of correcting the AG for the net protein charge.

TL;DR: It is observed that PI3-K is required for p70-S6-K activation by IGF-1 and PDGF, and is partially responsible for PDGF-induced ERK activation, which is important for perpetuating the activated state of HSC during fibrogenesis.

TL;DR: It seems unlikely that MPs from preeclamptic patients induce endothelial dysfunction by directly affecting the expression of inflammation-related genes in these cells, because incubation with IL-1alpha triggered substantial changes in RNA expression in endothelial cells.

TL;DR: Compared with other ASA regimens, L-100 twice-daily reduced by >50% the proportion of patients with suboptimal inhibition of platelet recruitment in WB and inhibited 14C-5HT release to the greatest extent.

TL;DR: The calculated free water ABE effect was offset by opposite changes in calculated chloride, lactate, phosphate, and albumin ABE effects, which would be useful in the interpretation of the effect of changes in free water in patients.

TL;DR: The data suggest that IFN-gamma/JAK/STAT pathway, which is supposed to be activated in inflammatory rheumatoid arthritis (RA) synovial tissues, contributes to form apoptosis resistance phenotype of the cells in situ, leading to a marked increase in cellularity ofsynovial cells.

TL;DR: It is suggested that men with PCa have higher ATT levels than those without PCa; and African-American men without PCA have higher Att levels than Caucasian men.

TL;DR: In this paper, the authors investigated the difference between a new office-based stool immunoassay (ImmunoCard STAT! HpSA) and (13) C-Urea Breath Test ((13)C-UBT).

TL;DR: There was an excellent correlation between the mean 24-hour glucose concentration and the %tGHb among subjects with diabetes and the correlation was poor among subjects without diabetes, and the relationship was curvilinear when plotted as a single group.

TL;DR: The results demonstrated that the integrin antagonist, Gly-Arg-Gly-Asp (GRGD), increased the percentage of cells with apoptosis (from 0.9±0.5% to 27.2±9.9%, P P).