Showing papers in "Journal of Neuroscience Methods in 1998"

TL;DR: Results of the reported experiments indicate that the UIEA can be successfully used for limited times in a chronic recording application, and could form the platform for a cortical neuroprosthetic system.

TL;DR: This simple and novel culture method allows the rapid expansion of large numbers of non-transformed human neural precursor cells which may be of use in drug discovery, ex vivo gene therapy and clinical neural transplantation.

TL;DR: A method for impregnating the whole rat brain with Golgi-Cox stain and sectioning with the vibratome is described, which provides good resolution of dendrites and spines.

TL;DR: An on-line archive of neuronal geometry to encourage the use of realistic dendritic structures in morphometry and for neuronal modeling and to facilitate the quantitative use of full three-dimensional reconstructions of neurons from the hippocampus and other brain regions is developed.

TL;DR: It is shown that the annexin V-binding assay is also applicable to differentiated neuronal cells with fragile neurite outgrowths, and when the cells are incubated with Annexin V prior to harvesting, the former cell populations can be separated from cells damaged during isolation.

TL;DR: It is concluded that the ORP test is useful for evaluating motor deficit in MPTP-treated mice, and the effects of subsequent treatments.

TL;DR: Eleven monoclonal antibodies directed against various reelin epitopes were obtained, providing useful additions to the widely used antibody CR-50, and one anti-peptide antibody recognizes the highly basic C-terminal segment.

TL;DR: This paper reviews some novel spectral analysis techniques that are useful for neurological signals in general and EEG signals in particular and presents an auto-regressive (AR) modeling based spectral estimation procedure to overcome the problems of lower resolution and 'leakage' effects inherent in the FFT algorithm.

TL;DR: The reversible and renewable immersion technique was most effective in paraformaldehyde-fixed tissue where the preservation quality was improved such that labeled axons remained detectable for more than 1 year after initial preparation.

TL;DR: The results reinforce the idea that comparison of measurements of different profiles using the same measurement method may be useful and valid even if an exact numeric value of the dimension is not realised in practice.

TL;DR: High resolution substrates, created using patterned self-assembled monolayers, are shown to direct axonal and dendritic process extension at the level of a single hippocampal neuron, and may be used to study the role of fine scale spatial cues in neuronal development and synapse formation.

TL;DR: Efficient unbiased stereological techniques to estimate the total numbers and absolute size distributions of both myelinated and unmyelinated axons from a small sample of axons are described and evaluated.

TL;DR: A linear model for point process systems is introduced and the finite Fourier transform of this model leads to a regression type analysis of the relations between spike trains.

TL;DR: Using this non-invasive method of imaging brain activity in conscious animals, it is now possible to perform developmental studies in animal models of neurological and psychiatric disorders.

TL;DR: The results indicate that both embryonic and adult cultured neurons retain a clearly neuronal electrophysiological phenotype in Neurobasal/B27 serum-free medium.

TL;DR: Methods for preparing, visualizing, and recording from healthy perirhinal cortex neurons in brain slices from young and aging rats should benefit neuroscientists interested in applying visually-guided whole-cell patch-clamp techniques to brain slice experiments using aged tissue.

TL;DR: The presence of a variety of ion channels in the HEK 293 cells suggests that a great precaution needs to be taken when this expression system is used in studies of several similar ion channels.

TL;DR: It is demonstrated that ischemic lesion of focal cerebral ischemia in rat can be accurately and reproducibly quantified using this method, and the low-cost and simplicity of this method may facilitate the application in determination of isChemic damage.

TL;DR: In vivo results suggest reliable glucose monitoring in brain ECF and indicate that changes in O2 and AA, the principal endogenous interferents, have minimal effect on the response of these first generation biosensors.

TL;DR: In both systems, movements of a single whisker may be monitored 'on-line' with high spatial and temporal resolution; in one case with, in the other without the presence of neighboring whiskers.

TL;DR: The electronic algometer allows standardization of testing, detailed documentation of each experiment and provides an objective and accurate method for measuring the reactions of test animals to mechanical stimuli.

TL;DR: A new, computer controlled, automated procedure for assessing conditioned freezing in rats and its development over time is described, in response to contextual cues and to a discrete tone which had been paired with foot shock.

TL;DR: In the present paper applications of SDF in analysis of the firing patterns of Lymnaea neurons are described and its performance is compared to other quantitative methods.

TL;DR: This paper describes methods for visualizing auditory localization data without assuming that the principal components of the data are aligned with the coordinate system and collects together a set of spherical plotting and statistical procedures to visualize and summarize these data.

TL;DR: The combination of immunocytochemistry and stereology provides a reliable means to assess microglia number that can easily be adopted for studies of transgenic and lesion-based models of aging and neurodegenerative diseases.

TL;DR: Computer algorithms that correct capacitative filtering that results from pipette series resistance as well as the voltage error for current responses with either linear or non linear current voltage curves are described.

TL;DR: The high performances observed with systems based on neural networks highlight the need to integrate these tools into the field of sleep research and the heterogeneity of the different processing approaches in sleep research.

TL;DR: It is concluded that the AR modelling approach can produce tremor spectra that are superior to those from FFT-based methods for short data sequences and for providing information about the physiological mechanisms of tremor generation are not yet clear.

TL;DR: The technique is used for classifying sensory neurones in culture with respect to their sensitivity to heat and algogens; however, it is applicable to any study of the effects of increased temperature on the activity of ion channels in cultured cells.

TL;DR: It is demonstrated that a low intra-individual variability of COX assay can be obtained with SWS by: using manual stirrers to avoid the formation of bubbles in the mixture, and preincubating mitochondria and laurylmaltoside before the addition of cytochrome c, which prevents light scattering secondary to mitochondrial swelling.