Showing papers in "Kidney International in 1989"
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TL;DR: Left ventricular hypertrophy appears to be an important, independent, determinant of survival in patients receiving therapy for end-stage renal failure in patients beginning renal replacement therapy.
785 citations
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TL;DR: Elevated venous dialysis pressure is a reliable method of detecting fistula stenoses and that the elective treatment of these stenoses significantly decreases fistula thrombosis and fistula loss.
396 citations
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TL;DR: A 40-year-old man has undergone chronic hemodialysis for 7 years and had nephrotic syndrome from age 2 to 5 years but was apparently well until age 18, when proteinuria was detected again.
371 citations
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TL;DR: The antiproteinuric effect of the ACE inhibitor lisinopril appears to be dose and time related, and is strongly dependent on dietary sodium restriction, whereas it does not depend on initial proteinuria, BP, or GFR.
365 citations
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TL;DR: While no single morphologic feature of HIVN is specific, the combination of clinical and pathologic findings is quite distinctive and permits a presumptive diagnosis of HIVn in otherwise asymptomatic carriers.
364 citations
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TL;DR: This work studied the functional and morphological sequelae of nephrectomy and those of unilateral ureteral diversion into the peritoneal cavity of rats with chronic renal diseases to investigate a possible causal link between the glomerular hyperfunction and hypertrophy.
363 citations
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TL;DR: Results confirm the clinical observation that antihypertensive therapy slows diabetic glomerulopathy, but also suggest that CAP affords superior long-term protection as compared to the other anti Hypertensive drug regimen studied.
320 citations
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TL;DR: A 64-year-old man was admitted to the hospital for evaluation of progressive dyspnea and increasing angina and showed normal sinus rhythm and evidence of an old, anteroseptal myocardial infarction.
292 citations
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265 citations
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TL;DR: In vivo pretreatment with 1,25(OH)2D3, either by intermittent i.p. injection or by osmotic minipump, dose-dependently decreased 3H-thymidine incorporation and parathyroids cell mitoses without affecting morphometric indices of parathyroid cells.
264 citations
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TL;DR: In a large group of patients who have progressed to ESRD, there is an association between control of diastolic blood pressure and a slower rate of decline in renal function.
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TL;DR: Blood peritoneal clearances of various endogenous solutes in patients undergoing continuous ambulatory peritoneAL dialysis (CAPD) were evaluated according to recent developments of the two-pore theory of membrane permeability, using a non-linear transport formalism for the analysis.
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TL;DR: Enalapril and triple drug therapy, at equi-depressor doses in regard to systemic blood pressure, had identical potency in sparing glomerular structure, and this antisclerotic potency appears to be related to the drugs' potency to inhibitglomerular growth rather than an effect on the abnormal hemodynamics which develop in the glomerulus.
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TL;DR: An otherwise healthy, 27-year-old white female went to her local physician complaining of 2 weeks of fever, malaise, and poor appetite and was admitted to the hospital, where a renal biopsy was performed subsequent to a diagnostic ultrasound examination, blood cultures, and a urine culture.
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TL;DR: In this review attention was paid mainly to the validity of lithium clearance as a pure "proximal marker" and many of the interpretations suffer from incomplete certainty with respect to the renal effects of tested maneuvers.
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TL;DR: The role of prostaglandin E2 (PGE2) was determined to assess the mechanisms whereby TNF production was regulated, and it was found that PGE2 acted in a negative feedback manner to regulate the production of TNF.
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TL;DR: During acute rHuEPO therapy net body iron balance remained neutral in patients receiving no iron supplements and increased 5 mg/kg in patients prescribed oral ferrous sulfate, however, in patients given iron dextran i.v. less than 60% of elemental iron administered became measurable as iron stores or usable for hemoglobin synthesis.
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TL;DR: The mechanism of the diuretic braking phenomenon was studied in nine male hypertensive patients by assessing the diurnal pattern of renal sodium excretion during furosemide therapy, and the response to a test dose of furo Semide infused alone and with chlorothiazide.
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TL;DR: In this paper, a population of 96 patients insuffisant renaux suivis pendant 14 mois, le taux de filtration glomerulaire and l'index 1/creatininemie sabaissent.
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TL;DR: It is concluded that KHCO3 promotes more positive Ca balances by either enhancing renal Ca retention or skeletalCa retention or both and NaHCO3 administration was accompanied by equivalently more positive Na or K balances, respectively and equivalent more negative acid balances (H CO3 retention).
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TL;DR: The formation of insoluble IC produces complement activation and inflammation at the site of the immune aggregate and the deposition of circulating complement-fixing IC in various organs may be considered as a failure of this transport system.
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TL;DR: This finding suggested progression of secondary hyperparathyroidism (HPT) only in group A patients, and an effective correction of acidosis was shown in group B by a higher predialysis plasma bicarbonate level.
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TL;DR: The effect of intravenous calcitriol on parathyroid function was evaluated in nine chronic hemodialysis patients with secondary hyperparathyroidism by inducing hypo- and hypercalcemia with low calcium and high calcium and the sigmoidal relationship between PTH and calcium was evaluated.
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TL;DR: The data suggest that MHD patients have normal energy expenditure and approximately normal requirements for maintenance of protein balance, body weight and body fat, and an average energy intake of about 38 kcal/kg desirable weight/day may be necessary to maintain nitrogen balance in these patients.
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TL;DR: The effects of well characterized cytokines on endothelial cells in vitro are reviewed, the role of endothelial activation in several clinical settings in vivo is examined, and those reactions that may be particularly relevant to renal injury are emphasized.
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TL;DR: Variability in the collagen chain composition of renal basement membranes was demonstrated by immunofluorescent microscopy using polyclonal and monoclonal antibodies and correlating with imaging of the glomerular basement membrane by phase microscopy.
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TL;DR: Systemic and regional hemodynamics studies in 11 hemodialysis patients before and 10 to 35 weeks after initiation of rHuEpo therapy showed that r HuEpo treatment led to a decrease in left ventricular end-diastolic diameter and aortic diameters, and echocardiographic study showed that there was no change in left atrial diameter.
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TL;DR: 1,25(OH)2D3 treatment was associated with a significant fall in serum phosphorus and alkaline phosphatase concentrations as well as with histological evidence of an amelioration of hyperparathyroid changes, and no deterioration of renal function attributable to the treatment occurred.
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TL;DR: The higher phosphorus binding/calcium absorption ratio coupled with a lower dose indicates that less calcium will be absorbed when calcium acetate is used for phosphorus control, which should be less likely to occur with this drug than other calcium salts.