Showing papers in "Natural Product Research in 2008"

TL;DR: In this article, the essential oil composition of Pimpinella anisum L. fruits obtained from different geographical areas of Europe were determined using capillary GC and GC-MS techniques.

TL;DR: In this article, a screening of antibacterial activity and toxicity of 22 aqueous plant extracts from 17 Turkish plants was conducted, including Tussilago farfara leaves, Helichyrsum plicatum flowers, Solanum dulcamara aerial parts and Urtica dioica leaves.

TL;DR: In vivo experiments showed that the five components exhibited significant inhibiting effects both on the ear edema induced by xylene and on the peritoneal capillary permeability induced by acetic acid in mice.

TL;DR: The essential oil tested was weak antioxidant and induced cytotoxicity in different cell types by a mechanism related to apoptosis, indicating that apoptosis is the main mechanism of toxicity induced by S. molle essential oil in this cell line.

TL;DR: The results show that the gorgonian coral S. suberosa and S. gracillis can produce potent anti-fouling compounds that deserve further exploration.

TL;DR: The authors in this paper selected 15 species of Tunisian traditional medicinal plants, belonging to 10 families, and evaluated their antiviral activity against Herpes simplex virus type 1 (HSV-1), using neutral red incorporation.

TL;DR: Cryptomeria japonica bark extract and its diterpenoids, ferruginol and isopimaric acid, have the ability to inhibit the bacterial growth and can be used as the source for natural bactericides.

TL;DR: A new labdane diterpenoid, (E)-labda-8(17),12-dien-15,16-olide together with eight known compounds, coronarin D, together with epimeric mixtures of 2 and 3 have not been reported before and were evaluated for their cytotoxicity.

TL;DR: This is the first report of antioxidant activity in this plant and the antioxidant activities of the two dihydrochalcones were very weak.

TL;DR: Result presented here may suggest that the essential oil of D. heterophyllum posses antimicrobial and antioxidant properties, and therefore, they can be one of new medicinal resources for antimicrobial agent and/or used as a natural preservative ingredient in food and cosmetics and pharmaceuticals industry.

TL;DR: CP has exhibited potent memory-enhancing effects in the step-down and shuttle-box avoidance paradigms and further studies are necessitated to identify the exact mechanism of action.

TL;DR: It is concluded that oral administration of gum arabic could conceivably alleviate adverse effects of chronic renal failure and should be considered as a potential treatment option for CRF.

TL;DR: The saponin constituents extracted from M. charantia in an aqueous two-phase extraction system induced significant hypoglycaemic activity in hyperglycaemic and normal mice.

TL;DR: The results indicated that globulol could be a main antimicrobial compound in the ethanol crude extract of E. globulus fruits.

TL;DR: Three known compounds, 5,7-dimethoxy-6-methylflavone (9), hoslunddiol (10) and euscaphic acid (11) were isolated from H. opposita and it was found that compounds 2, 4 and 9 inhibited the HIV-1 reverse transcriptase enzyme by 91, 53 and 52%, respectively, at 100 µg mL−1.

TL;DR: The viral binding assay showed that the extract of lemon balm does not prevent the entry of HSV-2 in the cells, thus suggesting a mechanism of action subsequent to the penetration of the virus in the cell.

TL;DR: Antifungal bioassay-guided fractionation of Combretum nelsonii leaf extracts afforded two closely related triterpenes, asiatic acid and arjunolic acid which were determined against five fungal animal pathogens and Aspergillus fumigatus was the most resistant.

TL;DR: Results indicate that an ideal extraction process was obtained at 5000 psi and 80°C with an extraction yield of 4.27% (w/w) and rich in phenolic antioxidants CA and CAL as contents of 35.23 and 0.46 mg g−1 in extract, respectively.

TL;DR: The modulatory effect of mangiferin on mitochondrial lipid peroxidation, tricarboxylic acid, cycle key enzymes and electron transport chain complexes was investigated against lung carcinogenesis induced by benzo(a)pyrene in Swiss albino mice and these results are consistent with the hypothesis that mangifer in is a promising chemopreventive agent.

TL;DR: A new acylated apigenin glucoside was isolated from the methanolic extract of the leaves of Phyllanthus emblica L. (Euphorbiaceae) and their chemical structures were elucidated on the basis of spectroscopic studies.

TL;DR: Flow cytometry analysis showed that it could markedly increase accumulation of sub-G1 phase, which suggested that this enzyme could induce apoptosis, and ACTX-6 could effectively inhibit tumor growth and it is a potential substance to develop into an antitumor drug.

TL;DR: Subamone's cytotoxic activities were evaluated against A549, DU-145 and LNCaP (human prostate cancer cell lines) and its cytotoxicity was found to be significantly against L NCaP rather than DU- 145 and A549 cancer cell Lines.

TL;DR: The results showed that the chamomile extract in the form of rubbing oil had a good potential for acceleration of burn wound healing in rats, and there was significant difference between vehicle and treatment groups.

TL;DR: A new 24-membered ring lactone was isolated from a culture broth of marine Bacillus sp.

TL;DR: It was observed that the content of small-molecular phenolic compounds had greater influence on the activity of extracts than tannins, and cation 2,2′-azini-di-(3-ethylbenzthiazoline sulphonate) ABTS•+.

TL;DR: Oil content in sweet and bitter fennels was obtained 12.22% and 14.41%, respectively, and trans-Anethole, estragole and fenchone were found to be the main constituents in both fennel.

TL;DR: The phytochemical study on the aerial parts of Cyperus rotundus L. led to the isolation of a fructose-amino acid conjugate, N-(1-deoxy-α-D-fructos-1-yl)-L-tryptophan, which was elucidated on the basis of spectroscopic methods.

TL;DR: Variations in the essential oil composition of Thymus serpyllum L., growing wild in Estonia and in some other countries (Russia, Latvia and Armenia, seven samples) were determined.

TL;DR: There may be a potential role for essential oils in the development of novel anticaries treatments after in vivo experiments conducted on male and female volunteers who brushed with essential oil blended toothpastes indicated that lower concentrations of the oils were significantly higher and effective during the course of the study as compared to chlorhexidine.

TL;DR: The present communication deals with some studies on the antibacterial, physico-chemical and phytochemical parameters of different extracts of Eucalyptus citriodora leaf, which revealed the most susceptible bacteria was C. freundii, while the most resistant was P. vulgaris.