Showing papers in "Neuroscience & Biobehavioral Reviews in 1983"

TL;DR: A 'septo-hippocampal syndrome,' consisting of the effects common to both lesions, is delineated, and divergences between the effects of the two lesions are noted.

TL;DR: It is suggested that the feeding profile of the animal provides important clues as to whether or not the animal has an opiate-sensitive feeding system, and interactions with ingested nutrients and the milieu interieur provide an important means by which animals modulate the opiates-entrained feeding drives.

TL;DR: It is concluded that at least six of these methods appear to do a reasonable job of excluding gross performance deficit in ICSS, and self-regulation of current intensity constitutes a powerful tool that has yet to realize its full potential in the pharmacological study of ICSS.

TL;DR: In this article, the triazolopyridazines, a new class of drugs, may be promising compounds for treatment of withdrawal with a more specific mode of action and fewer side effects.

TL;DR: Structural differentiation and/or size of allocortical limbic structures are clearly more advanced in higher primates and man than in low (basal) Insectivora and the opposite trends imply the existence of two functional systems in the allocortex being predominantly independent of one another.

TL;DR: It is unlikely that the atypical antipsychotics and antiparkinsonian agents interact with only one subtype of DA receptor, or have their therapeutic actions only through that receptor, and other pharmacological characteristics of these agents are more critically involved in their unique behavioral effects.

TL;DR: Evidence concerning an involvement of gonadal hormones in sensory function of man and animal is reviewed and it is suggested that such involvement does exist and that hormones exert their influence in two ways: by acting directly upon discrete peripheral structures and by affecting the processing of certain stimuli by the central nervous system.

TL;DR: It is concluded that besides the short-lived ictal abberations of mental state and emotional sphere ("psychical seizures") also some of the more prolonged behavior and personality changes seen frequently in patients with bitemporal basal spike foci might be attributed to narrowly confined limbic seizure discharges or to a "limbic dyscontrol syndrome" based on the altered activity of limbic structures due to the spikefoci.

TL;DR: The similarity between environmental and genetic effects on these variables suggests that the above changes have a common adaptive function.

TL;DR: It is suggested that the noradrenergic system may be involved in the expression of extinction behavior by a role in selective attention, the dopamine system via an involvement with secondary reinforcement, the cholinergic system by a mechanism of response inhibition and the barbiturates and benzodiazepines by a block of nonreward.

TL;DR: The various central effects of neurohypophyseal hormones involve different mechanisms which can be distinguished from one another on the basis of required dose, time-course of action, and structure-activity relationships.

TL;DR: The hyperreactivity of SHR rats to stressful stimulation is not necessarily related to the development of hypertension but may be a valuable marker of the predisposition to develop high blood pressure in rats of the SHR strain.

TL;DR: The hypothesis is made that potentially lethal disease does not usually occur in healthy animals or people but does so when covert or overt disease exists or when a predisposition for disease exists.

TL;DR: Results revealed that neurotensin significantly increased the hypothermia induced by apomorphine and N-n-propylnorapomorphine, and possible mechanisms which could underly neurotens in's selective inhibitory action on hyperactivity produced by both pre and post synaptic dopaminergic stimulation are discussed.

TL;DR: It is suggested that it may be more appropriate to view stress-induced receptor subsensitivity as part of a more complex pattern of adaptive changes which includes alterations in the size, number, efficiency and output of CA effector cells.

TL;DR: The present review has extended the general theory of motion sickness by identifying specific neurophysiological mechanisms that are involved in motion sickness and by interpreting the actions of both scopolamine and amphetamine as effective anti-motion sickness drugs within this neurophysiology context.

TL;DR: It can be concluded that the effects of vasopressin in the terminal regions of the coeruleo-telencephalic noradrenalin system correlate with its effects on consolidation of memory.

TL;DR: It is proposed that estrogen acts upon metabolically specific and unique neural elements in the hypothalamus whose function is to translate error signals derived from the long-term integration of body nutrients into appropriate readjustments in feeding behavior, which can influence the efficiency with which nutrient loads of fats and proteins can modify subsequent feeding behavior.

TL;DR: The results indicate that much of the limbic system suppresses quiet biting attack behavior, and the most potent inhibitory effects were obtained from the basomedial amygdala and the prefrontal cortex.

TL;DR: This paper compiles and reviews animal and selected human literature in this research area and shows that animal studies show that long-lasting functional tolerance to drugs develops following early barbiturate exposure, and that in humans treated with barbiturates, hormone levels remain within the normal range.

TL;DR: The outcome of this review suggests that the incidence of recurrent attacks of TGA is higher than previously assumed and that a transient global amnesic attack may be followed by lasting behavioral deteriorations.

TL;DR: Development of an appropriate animal model for examining the atherogenic effects of psychosocial variables is attempted and periodic social group reorganization led to development of greater atherosclerosis in the coronary arteries.

TL;DR: Interest has returned to a second implication of evolution: The authors should expect to find not only similarities among species, but also divergences and adaptation to specific problems.

TL;DR: Clinical analysis of 40 cases of traumatic apallic syndrome is based on clinical analysis of 30 of whom developed a complete or partial Klüver-Bucy syndrome during recovery, and the delineation between a pre-stage, full-stage and remission-stage of the Klüer- Bucy syndrome is suggested.

TL;DR: It is concluded that a combined method of a sociobiological perspective using established experimental procedures will offer unique opportunities for the investigation of specific predictions suggested by kin selection theory.

TL;DR: Bilateral lesion of the anterior cingulate cortex in man should hamper the volitional control of emotional vocal utterances in man as it does in monkeys.

TL;DR: This paper reviews the clinical literature relevant to the association between aggressive behavior and the limbic system in humans to identify areas of review related to aggressive behavior related to naturally occurring and iatrogenic brain lesions.

TL;DR: Neuropsychiatric investigation revealed developmental lags in speech and other psychosocial skills and a circumscribed lesion (cystic defect) lateral to the right nucleus amygdalae in a 14-year-old male who killed an 8- year-old child following an alleged insult.

TL;DR: Results of research on imprinting and developmental neurobiology of the visual cortex are compared to evaluate the evidence for or against a frequently hypothesized linkage of the two phenomena.