Showing papers in "Neuroscience Letters in 1980"
••
TL;DR: Preliminary evidence indicates that this reduced glutamate content is not due to neuroleptic treatment, and is interpreted by the hypothesis that there is a dysfunction or degeneration of glutamatergic neurons in schizophrenia.
711 citations
••
TL;DR: Two new fluorescent retrograde neuronal tracers are reported: Nuclear Yellow (Hoechst S 769121), which mainly labels the neuronal nucleus; and Fast Blue (diamidino compound 253/50, which mainlylabel the neuronal cytoplasm), which seem to be transported effectively over long distances in rat and cat.
457 citations
••
TL;DR: A significant fall in ChAT activity was observed in the cortex, hippocampus and amygdala of the SDAT cases and was maximal in the temporal cortex, accompanied by a significant reduction in immunoreactive somatostatin.
426 citations
••
TL;DR: Dopaminergic afferents to the rat hippocampal formation originate from the A10 and A9 dopaminergic cell groups, and the 'anterior' hippocampusal formation receives a major input fromThe A10 area whereas the 'posterior' hippocampal region receives dopamine and DOPAC contents from both A9 and A10 cell groups.
332 citations
••
TL;DR: Observations tend to support a recent suggestion that there may be a particular form of pyruvate dehydrogenase associated with cholinergic neurones, as shown by the regional distribution of choline acetyltransferase.
235 citations
••
TL;DR: It is suggested that MLR stimulation may give rise to locomotion by activation of pontine and medullary reticulospinal pathways projecting through the ventrolateral quadrant.
172 citations
••
TL;DR: This migration was found to take place both in vivo and in vitro during storage of the sections in water, and when using the tracers in 1% concentrations the in vivo migration may be controlled by restricting the survival time.
166 citations
••
TL;DR: The site of origin of a direct projection from the amygdala to autonomic regulatory nuclei in the dorsomedial medulla has been precisely localized and delimited in the rabbit by means of the retrograde axonal transport of horseradish peroxidase.
148 citations
••
TL;DR: Transganglionic transport of horseradish peroxidase was greatly improved by conjugating the enzyme with wheat germ agglutinin (WGA) and constitutes a valuable advance in HRP technique.
145 citations
••
TL;DR: A rapid thionin stain is introduced which, after stabilizing the TMB-based reaction product in methyl salicylate, causes no detectable loss of HRP labelled neurons.
140 citations
••
TL;DR: The results indicate that SP, apart from its direct action on the LM, also activates cholinergic neurones innervating the LM.
••
TL;DR: Findings after injections of two different tracers in the same animal suggest that about 15% of the labeled neurons in the above areas distribute divergent axon collaterals to both the medulla and the spinal cord.
••
TL;DR: Sudden withdrawal of extracellular Mg 2+ from the medium produced contraction of arterial smooth muscle, whereas elevated concentrations of magnesium [Mg] o decreased the basal tensions in a concentration-dependent manner.
••
TL;DR: Using a radioimmunoassay technique levels of dynorphin-immunoreactivity (dyn-ir) have been measured in the brain and pituitary of rats, indicating that a substantial part of the dyn-ir measured represented biologically active material.
••
TL;DR: Evidence is presented for the existence of serotonergic as well as non-serotonergic projections from the nucleus raphe dorsalis to the caudate-putamen complex by Immunofluorescence combined with retrograde axonal tracing by propidium iodide.
••
TL;DR: With this technique, the neurons innervating the different muscles can be demonstrated simultaneously and in both cats and dogs neurons labeled with PI were concentrated dorsomedially in Onuf's nucleus, while those labeled with BB were concentrated ventrolaterally.
••
TL;DR: A retrograde labeling procedure utilizing fluorescent substances was used to establish the presence of branching axons in the ascending raphe system of young rats, and each class of neurons, i.e. single-, double- and triple-labeled, were shown to have a predominant distribution within specific parts of the nucleus.
••
TL;DR: The present method results in highly rapid and sensitive visualization of monoaminergic neurons and their axonal varicosities in body tissue.
••
TL;DR: Crossed and descending projections to the inferior colliculus of the cat were studied following injections of horseradish peroxidase and 16 cell types were described.
••
TL;DR: It is suggested that mesolimbic and mesocortical DA neurons are necessary for normal exploratory behavior in the rat.
••
TL;DR: Artificial opening of the eyes of young rabbits on the 5th postnatal day led to accelerated myelination: the myelin-specific basic and proteolipid proteins nearly doubled and AChE activities presumably reflected elevated myelin/axolemma ratios.
••
TL;DR: Renin-like immunoreactivity could be demonstrated in the nuclei paraventricularis, periventricularIS and supraopticus of the hypothalamus and in the cerebellar cortex of rats and mice, consistent with the assumption of an endogenous angiotensin-forming system in the brain.
••
TL;DR: This result supports the finding that pentobarbitone enhances synaptic inhibition mediated by GABA, and abolishes the enhancement of GABA binding in the presence of picrotoxinin.
••
TL;DR: Minimal conduction velocities of peripheral nerves contributing to acute thermal pain sensation in human volunteer subjects were calculated and cerebral responses were found to preclude C fiber peripheral activity from this phenomenon.
••
TL;DR: Single vestibular neurons functionally identified as secondary neurons receiving primary afferents from the horizontal canal in the cat were intracellularly stained with horseradish peroxidase and distributed terminal branches in a relatively narrow band in the nucleus.
••
TL;DR: The results suggest an involvement of SP-innervation in the regulation of coronary blood flow, and substance P-immunoreactive nerve fibers and varicosities were identified in the adventitial layers of the aorta, the pulmonary trunk and the coronary arteries and veins in the guinea pig heart.
••
TL;DR: A combined technique of dry-mount autoradiography and immunoperoxidase staining and results suggest a direct action of estradiol on neurohypophysial hormone producing cells of the mouse supraoptic and paraventricular nucleus.
••
TL;DR: During and after degeneration of the optic nerve afferents in the rat suprachiasmatic nucleus (SCN) postsynaptic density material is added to existing symmetrical and asymmetrical appositions of non-optic synapses on optic target neurons.
••
TL;DR: The results suggest that the behavioral actions of beta-endorphin and smaller beta-lipotropin sequences such as gamma- endorphin, are distinct, and that 0.1-100 micrograms/kg of either alpha-Endorphin or Met-enkephalin given before or after training was without effect on retention of the response.
••
TL;DR: Neither the cerebral cortex nor the cerebellum are necessary parts of the neural circuitry generating longer latency components of the electromyographic response to muscle stretch in lightly anaesthetized monkey and cat.