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Showing papers in "New Biotechnology in 2011"


Journal ArticleDOI
TL;DR: The progress made in antibody production is examined as well as the future of manufacturing for these molecules, including the emergence of single use technologies are discussed.

185 citations


Journal ArticleDOI
TL;DR: The plant oil-like fatty acid composition of yeast and microalgal lipids suggested their high potential for use as biodiesel feedstock.

174 citations


Journal ArticleDOI
TL;DR: A successful reactor performance indicates the large potential for the industrial application of MaB-flocs for flue gas sparged sewage treatment.

115 citations


Journal ArticleDOI
TL;DR: A granular activated carbon based microbial fuel cell (GACB-MFC) was used without using any expensive materials like Nafion membrane and platinum catalyst for simultaneous decolorization of real dye wastewater and bioelectricity generation.

113 citations


Journal ArticleDOI
TL;DR: An overview of the recent advances of cell-free production of membrane proteins for structural and functional analysis and the array of currently available options to modify and develop cell- free expression protocols adapted to the specific requirements of individual membrane proteins are given.

99 citations


Journal ArticleDOI
TL;DR: The optimum menaquinone-7 concentration was in good agreement with the predicted value by the model (96% validity), and this value is the highest concentration reported in the literature.

93 citations


Journal ArticleDOI
TL;DR: Quercetin exhibited a potential protective effect on t-BHP-caused injury in hepatocytes through the induction of MT, and this results suggest that quercet in is a natural antioxidant in the diet and the consumption of foods that are rich in quercETin could be beneficial for the prevention of environmental oxidant-induced liver damage.

92 citations


Journal ArticleDOI
TL;DR: Findings suggest protease secreted by P. aeruginosa MCM B-327 may have application in dehairing for environment-friendly leather processing and Kinetic studies indicated that substrate specificity of PA02 protease was towards various natural and synthetic proteolytic substrates but inactive against collagen and keratin.

84 citations


Journal ArticleDOI
TL;DR: Results indicated the scope for potential application of this marine fungal lipase in bioremediation, and an overall 4.6-fold increase in lipase production was achieved.

84 citations


Journal ArticleDOI
TL;DR: The present report describes production of 1,3-propanediol by Klebsiella pneumoniae ATCC 15380 from crude glycerol from jatropha biodiesel process, which resulted in 99.7% pure product with a recovery of 34%.

80 citations


Journal ArticleDOI
TL;DR: An overview of mAbs approved for use in clinical oncology and those currently in clinical development is provided and the mechanisms of action of anti-cancer mAbs are discussed, as well as the antigen targets recognised by these antibodies.

Journal ArticleDOI
TL;DR: The fungal treatment, although less efficient than ozonation, caused a good decolourisation of the effluent, with colour values within the threshold limits of the Italian law; both the fungal and the ozone treatment caused a detoxification, but only towards one of the three organisms used for the ecotoxicological tests.

Journal ArticleDOI
TL;DR: The question is not whether antibodies have a bright future for infectious agents, but rather what formats are cost effective and generate safe and efficacious treatments to satisfy regulatory approval.

Journal ArticleDOI
TL;DR: The novel xylanase, reported in this study is a halotolerant enzyme from marine isolate and can play a very important role in bioethanol production from marine seaweeds.

Journal ArticleDOI
Thomas Tiller1
TL;DR: Various single B cell approaches are summarized and their use for the discovery of mAbs with potential therapeutic values or in basic research is described.

Journal ArticleDOI
TL;DR: The optimization process yielded highest titer value of laccase reported to date and the interactions between different parameters of fermentation were studied using response surface methodology.

Journal ArticleDOI
TL;DR: High-yield production of polyhydroxyalkanoates (PHAs) by Ralstonia eutropha KCTC 2662 was investigated using soybean oil and γ-butyrolactone as carbon sources and the optimum carbon to nitrogen ratio (C/N ratio) giving the highest cell and PHA yield was 20 g-soybean oil/g-(NH(4))(2)SO(4).

Journal ArticleDOI
TL;DR: An alkaline-fibrinolytic protease-producing bacterial strain isolated from a soil sample in Assam was a Gram-negative rod and grown at temperatures ranging from 25 to 55 °C, and pH 6.5 to 11.0, suggesting that its future application in pharmaceutical industry as thrombolytic and anticancer drugs is highly promising.

Journal ArticleDOI
TL;DR: A laboratory experiment was carried out to test the efficiency of a mixture of compost and straw in bio-degrading different mixtures of fungicides usually applied in vineyards, showing that the biomixture had a good capability of degrading pesticides.

Journal ArticleDOI
TL;DR: Thermostable lipase produced by a genotypically identified extremophilic Bacillus subtilis NS 8 was purified 500-fold to homogeneity with a recovery of 16% by ultrafiltration, DEAE-Toyopearl 650M and Sephadex G-75 column.

Journal ArticleDOI
TL;DR: Of six alkalitolerant, extracellular protease producing bacterial strains isolated, DP2 displayed maximum activity, and was active over a broad range of elevated temperatures, and possessed thermostability that may have industrial significance.

Journal ArticleDOI
TL;DR: BSN1, a nattokinase, was purified from the culture supernatant of Bacillus subtilis TKU007 with shrimp shell wastes as the sole carbon/nitrogen source and was inhibited completely by PMSF, indicating that the BSN1 was a serine protease.

Journal ArticleDOI
TL;DR: Improved levels of xylanase and laccase biosynthesis were achieved by co-culturing the mutant P. ostreatus MTCC 1804, which appears productive for the development of mixed enzyme preparation with tremendous potential for biobleaching.

Journal ArticleDOI
TL;DR: The characterization of an economic and ease-to-use carbon paste acetylcholinesterase (AChE) based biosensor to determine the concentration of pesticides Paraoxon and Dichlorvos is discussed and the comparison with the behavior of similar AChE based biosensors is presented.

Journal ArticleDOI
TL;DR: This research indicates that comprehensive biochemical analysis of plant products would facilitate the development of more reliable produce for use by the functional food/medicinal plant industry.

Journal ArticleDOI
TL;DR: Recently developed techniques available to produce functional membrane proteins are reviewed, and amphipols, nanodisc and styrene maleic acid lipid particle (SMALP) technologies that can be exploited alongside cell-free expression of membrane protein technologies are discussed.

Journal ArticleDOI
TL;DR: Investigation of the conditions for regenerating shoots from hypocotyl explants from four genetic lines showed Invigor plants were shown to regenerate more efficiently than Topas; the number of plantlets regenerated from Invigor was approximately 40-50% more as compared to Topas or Line 4079.

Journal ArticleDOI
TL;DR: The statistical experimental designs were adopted to optimize the culture medium in xylitol production by Candida tropicalis HDY-02 with corncob hemicellulose hydrolysate as substrate and the interactive effects of yeast extract and MgSO(4)·7H(2)O onxylitol yield were determined to be significant.

Journal ArticleDOI
TL;DR: The expression and function of DcHsp17.7, a small heat shock protein in carrot, were examined under salt stress, which is an exacerbating environmental condition due to water shortage and irrigation, and showed tissue-specific oligomer formation.

Journal ArticleDOI
TL;DR: High level production of an extracellular cellulase-poor alkali stable xylanase has been conceded from newly isolated Bacillus pumilus SV-85S under solid state fermentation using wheat bran as a substrate.