Showing papers in "Placenta in 1987"

TL;DR: In Placenta creta there is defective interaction between maternal tissues, particularly decidua, and migratory trophoblast in the early stages of placentation resulting in undue adherence of the placenta or penetration into the uterus coupled with the development of an abnormal uteroplacental circulation.

TL;DR: A small proportion of the syncytial knots, sprouts and bridges in the last-trimester placenta, those containing coarse pyknotic nuclei, are trophoblastic specializations of a probably degenerative character.

TL;DR: Stereological methods were used to test whether or not altitudinal, ethnic and sex differences in birthweight in Bolivia are associated with differences in placental morphology and structural differences are discussed in the context of their likely impact on placental functioning.

TL;DR: The findings of this study suggest that, among the pathogenic mechanisms responsible for the observed placental changes, uteroplacental ischaemia is probably a dominant factor, and that any ill effects on fetal growth and viability are very likely to be related to the inadequate maternal supply of oxygen and nutrients.

TL;DR: Human placental villi from both normal and complicated pregnancies were examined and it is found that histological features such as syncytial sprouts, bridges, and a net-like arrangement of villi represent tangential sections of irregularly shaped villi rather than proliferative activity of the villous surface.

TL;DR: In this article, the authors compared the incidence of postmolar sequelae in patients with homozygous and heterozygous moles, and established the androgenetic origin of complete hydatidiform moles in 84 of 91 cases.

TL;DR: Placentae from type I (insulin-dependent) pregnant diabetic patients, treated with continuous subcutaneous insulin infusion (CSII), were studied morphologically, indicating that near normoglycaemia, achieved with CSII, does not modify the morphological expression of the disease in the placenta.

TL;DR: In an elective study of 163 hydatidiform moles 38 were classified as partial mole (PHM) and 125 as complete mole (CHM) on the basis of pathology, and genetic studies showed the PHM to be triploid with one maternal and two paternal chromosome sets.

TL;DR: Perfusion fixation resulted in a lower coefficient of variation for many parameters compared with traditional immersion fixation, and it is considered that perfusion fixation will make true interplacental variations easier to detect.

TL;DR: In serial semithin sections mitoses of Hofbauer cells, as well as those of other cellular components of the villous stroma, were generally easily identified and thin sections were helpful in differentiating this cell type from the fixed stromal cells.

TL;DR: Ten cases of recurrent intrauterine growth retardation have been described; a high incidence of severe CVUA was found in both first and successive pregnancies, and it is suggested that subsequent pregnancies with the same father might be similarly affected.

TL;DR: The asymmetry of the transplacental amino acid flux is favoured by rapid uptake from the maternal circulation and transfer towards the fetus both rates exceed those observed in the reverse direction.

TL;DR: Oncomodulin was detected by immunocytochemical means in human placenta and found to occur in the cytotrophoblastic shell during implantation, in Langhans type villar cytotophoblastic cells, and in extravillar cytOTrophoblast or intermediate trophoblast.

TL;DR: Immunohistochemical localization of HLA antigens and plancental proteins in villous and extravillous trophoblast at various stages of normal human gestation were studied to strongly suggest that extravillus possesses many distinctive biological features and differs in an independent manner.

TL;DR: Trophoblast populations in four cases of placenta accreta were characterized using antibodies directed against cell membrane antigens, placental hormonal products and low-molecular-weight cytokeratins in standard immunoperoxidase techniques, suggesting it may regulate its development at an unfavourable intramyometrial implantation site by the production of hyaluronic acid.

TL;DR: The importance of defining the location of the sampling site in studies involving elemental analysis of the placenta is demonstrated, with significant variations found in the central and peripheral regions of the disc.

TL;DR: According to these observations, the segmental mesometrial arteries of pregnant guinea pigs show cytological and structural changes similar to those described for the mesometricrial arteries in the hamster and the spiral arteries in man.

TL;DR: Using flow cytometry, it was shown that two cases which were pathologically complete were in fact diploid, despite the finding of trisomy at one locus in the molar tissue using biochemical markers, and the most likely explanation of apparenttrisomy of the enzymes in themolar tissue was contamination by maternal tissue.

TL;DR: A role for the endogenous GnRH-like activity of the placenta in the control of placental hormonogenesis is indicated, as demonstrated by a gestational age-related action of this antagonist on placental hormonal release.

TL;DR: It is clear that changes in the thickness of vasculosyncytial membranes can take place independently of any alterations in the calibre of the underlying fetal capillary network.

TL;DR: It is concluded that this in vitro culture system is suitable for studying both m PL-II secretion and the differentiation of mPL-II-producing cells.

TL;DR: In this paper, immunoreactive peaks of β-endorphin and β-lipotrophin were detected in the syncytiotrophoblast in both early and term pregnancy.

TL;DR: Monoclonal antibody GB36, which was raised against human term syncytiotrophoblastic microvilli, was found to recognize a novel epithelial antigen and it is suggested that the antigen of GB36 may play a role in the polarity of epithelial cells and the adhesion of epithel cells to extracellular matrix.

TL;DR: On the basis of its lectin binding properties the EVT cell population was found to be heterogeneous and the expression of mannosylated and di-N-acetylchitobiosyl residues by a fetally derived cell invites speculation that such expression enables it both to invade host maternal tissues and to avoid any adverse host immunological response.

TL;DR: A possible role for trophoblast phagocytosis in early gestation is proposed with reference to the use of in vitro systems for examining developmental processes.

TL;DR: The ultrastructure of the placentae on day 20 of gestation was studied in rats made diabetic by streptozotocin injection on day 13 of gestation and a marked increase in glycogen content, together with higher numbers of glycogen cells in the junctional zone, was seen.

TL;DR: A possible role for the c-myc gene in proliferation of normal cells is discussed in the light of a strong correlation between myc transcript abundance and cytotrophoblastic proliferation.

TL;DR: A specific, membrane-bound, Ca2+-activated and Mg2-dependent adenosine triphosphatase (ATPase) activity is present in the human term placenta and is inhibited by phenothiazin and erythrosin B which also significantly inhibit active calcium in vitro by placental microsomal membrane vesicles.

TL;DR: It is concluded that Doppler flow velocity waveform analysis is a valuable and non-invasive method to assess impedance to blood flow through the placental circulation in pregnant sheep.