Journal ArticleDOI
3D printing of biomaterials with mussel-inspired nanostructures for tumor therapy and tissue regeneration.
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TLDR
The mussel-inspired nanostructures in 3D-printed bioceramic exhibited a remarkable capability for both cancer therapy and bone regeneration, offering a promising strategy to construct bifunctional biomaterials which could be widely used for therapy of tumor-induced tissue defects.About:
This article is published in Biomaterials.The article was published on 2016-12-01. It has received 153 citations till now. The article focuses on the topics: Bone regeneration & Tissue engineering.read more
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3D-printed bioceramic scaffolds: From bone tissue engineering to tumor therapy.
TL;DR: 3D-printed bioceramic scaffolds with different compositions and hierarchical structures (macro, micro, and nano scales), and their effects on the mechanical, degradation, permeability, and biological properties are focused on.
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2D-Black-Phosphorus-Reinforced 3D-Printed Scaffolds:A Stepwise Countermeasure for Osteosarcoma.
TL;DR: A black phosphorus (BP) reinforced 3D‐printed scaffold is designed and prepared to provide a feasible countermeasure for the efficient localized treatment of osteosarcoma and endows the scaffolds with unique physicochemical properties favoring the whole stepwise therapeutic process.
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3D printed porous ceramic scaffolds for bone tissue engineering: a review.
Yu Wen,Sun Xun,Meng Haoye,Sun Baichuan,Chen Peng,Liu Xuejian,Zhang Kaihong,Yang Xuan,Peng Jiang,Lu Shibi +9 more
TL;DR: This study summarizes the recent research status and development of three-dimensional (3D)-printed porous ceramic scaffolds in bone tissue engineering and suggests new classes of bone graft substitutes can be developed.
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3D printing of ceramic-based scaffolds for bone tissue engineering: an overview
TL;DR: This review aims to highlight advances in 3D printing of ceramic-based scaffolds for bone tissue engineering and discusses technical limitations and practical challenges, as well as design considerations.
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2D MXene-Integrated 3D-Printing Scaffolds for Augmented Osteosarcoma Phototherapy and Accelerated Tissue Reconstruction.
Shanshan Pan,Shanshan Pan,Junhui Yin,Luodan Yu,Changqing Zhang,Yufang Zhu,Yufang Zhu,You-Shui Gao,Yu Chen +8 more
TL;DR: The rational integration of 2D Ti3C2 MXene is demonstrated to efficiently accelerate the in vivo growth of newborn bone tissue of the composite BG scaffolds for achieving concurrent bone‐tumor killing by photonic hyperthermia and bone-tissue regeneration by bioactive scaffolds.
References
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Mussel-Inspired Surface Chemistry for Multifunctional Coatings
TL;DR: Inspired by the composition of adhesive proteins in mussels, dopamine self-polymerization is used to form thin, surface-adherent polydopamine films onto a wide range of inorganic and organic materials, including noble metals, oxides, polymers, semiconductors, and ceramics.
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Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
Donald W. Nicholson,Ambereen Ali,Nancy A. Thornberry,John P. Vaillancourt,C K Ding,Michel Gallant,Yves Gareau,Patrick R. Griffin,Marc Labelle,Yuri Lazebnik +9 more
TL;DR: A potent peptide aldehyde inhibitor has been developed and shown to prevent apoptotic events in vitro, suggesting that apopain/CPP32 is important for the initiation of apoptotic cell death.
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Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy
TL;DR: The biochemical, structural and genetic studies that have clarified how the interplay between members of the BCL-2 family on mitochondria sets the apoptotic threshold are discussed, illuminating the physiological control of apoptosis, the pathological consequences of its dysregulation and the promising search for novel cancer therapies that target the BCA2 protein family.
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Functional Nanomaterials for Phototherapies of Cancer
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PCNA, the Maestro of the Replication Fork
TL;DR: Proliferating cell nuclear antigen -a cofactor of DNA polymerases that encircles DNA-orchestrates several of these functions by recruiting crucial players to the replication fork, indicating that these interactions do not occur simultaneously during replication.