Journal ArticleDOI
5α-Reductase, an enzyme regulating glucocorticoid action in the testis of Rhinella arenarum (Amphibia: Anura).
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TLDR
In vitro experiments suggest that 5α-DHB is an agonist of toad testicular GR, decreasing the activity of the key enzyme for androgen synthesis, the cytochrome P450 17-hydroxylase, C17,20-lyase.About:
This article is published in General and Comparative Endocrinology.The article was published on 2012-05-01. It has received 6 citations till now. The article focuses on the topics: Corticosterone & Toad.read more
Citations
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Journal ArticleDOI
Effect of estradiol on apoptosis, proliferation and steroidogenic enzymes in the testes of the toad Rhinella arenarum (Amphibia, Anura).
TL;DR: Results suggest that E2 is involved in the regulation of testicular steroidogenesis and spermatogenesis, and reduces 3β-HSD/I activity during the post reproductive season and has no effect on testicular proliferation all year long.
Journal ArticleDOI
Seasonal changes and regulation of the glucocorticoid receptor in the testis of the toad Rhinella arenarum.
Eleonora Regueira,Alina Grisel Sassone,María Florencia Scaia,María Clara Volonteri,Nora R. Ceballos +4 more
TL;DR: It is suggested that seasonal changes in plasma melatonin and glucocorticoids modulate the effect of glucocORTicoids in the testis of R. arenarum.
Journal ArticleDOI
Estradiol and reproduction in the South American toad Rhinella arenarum (Amphibian, Anura).
María Florencia Scaia,María Florencia Scaia,María Clara Volonteri,Silvia Cristina Czuchlej,Nora R. Ceballos,Nora R. Ceballos +5 more
TL;DR: The effect of E2 on gonadotropins and testicular function is complex, not clearly understood and probably varies depending on the species, while the effect on LHβ mRNA is dual, since during the reproductive season estradiol increases the expression of LH β mRNA while in the non-reproductive season it has no effect.
Journal ArticleDOI
Effect of glucocorticoids on androgen biosynthesis in the testes of the toad Rhinella arenarum (Amphibia, Anura).
Silvia Cristina Czuchlej,María Clara Volonteri,Eleonora Regueira,Eleonora Regueira,Nora R. Ceballos,Nora R. Ceballos +5 more
TL;DR: Results suggest that GCs inhibit steroidogenesis in toad testes by reducing of cytochrome P450 17-hydroxylase activity via a GR-mediated mechanism.
Book ChapterDOI
Comparative Aspects of Vertebrate Adrenals
David O. Norris,James A. Carr +1 more
TL;DR: The role in non-mammals for cortisol and corticosterone in gluconeogenesis, the stress response, and aging are similar to those of mammals and natriuretic peptides antagonize Ang-II actions.
References
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Journal ArticleDOI
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
TL;DR: This assay is very reproducible and rapid with the dye binding process virtually complete in approximately 2 min with good color stability for 1 hr with little or no interference from cations such as sodium or potassium nor from carbohydrates such as sucrose.
Journal ArticleDOI
How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions.
TL;DR: This review considers recent findings regarding GC action and generates criteria for determining whether a particular GC action permits, stimulates, or suppresses an ongoing stress-response or, as an additional category, is preparative for a subsequent stressor.
Book ChapterDOI
Assay of inorganic phosphate, total phosphate and phosphatase
TL;DR: The method is about seven times as sensitive as the Fiske–SubbaRow procedure and involves less pipetting, but it is not very satisfactory for determining inorganic phosphate if labile phosphate esters are present in large excess.
Journal ArticleDOI
Stress and disorders of the stress system
TL;DR: Optimal basal activity and responsiveness of the stress system is essential for a sense of well-being, successful performance of tasks, and appropriate social interactions, which might impair development, growth and body composition, and lead to a host of behavioral and somatic pathological conditions.
Journal ArticleDOI
The amphibian tree of life
Darrel R. Frost,Taran Grant,Taran Grant,Julián Faivovich,Julián Faivovich,Raoul H. Bain,Alexander Haas,Célio F. B. Haddad,Rafael O. de Sá,Alan Channing,Mark Wilkinson,Stephen C. Donnellan,Christopher J. Raxworthy,Jonathan A. Campbell,Boris L. Blotto,Paul E. Moler,Robert C. Drewes,Ronald A. Nussbaum,John D. Lynch,David M. Green,Ward C. Wheeler +20 more
TL;DR: A new taxonomy of living amphibians is proposed to correct the deficiencies of the old one, based on the largest phylogenetic analysis of living Amphibia so far accomplished, and many subsidiary taxa are demonstrated to be nonmonophyletic.