754-3 Impact of Atrial Fibrillation on the Risk of Death: The Framingham Study
TLDR
AF has a negative impact on survival, independent of the preexisting cardiovascular conditions with which it is often associated, and the increased mortality of AF underscores the importance of its prevention.About:
This article is published in Journal of the American College of Cardiology.The article was published on 1995-02-01 and is currently open access. It has received 34 citations till now. The article focuses on the topics: Framingham Heart Study & Hazard ratio.read more
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Journal ArticleDOI
Impact of Atrial Fibrillation on Mortality, Stroke, and Medical Costs
TL;DR: Prevention of AF and treatment of patients with AF and associated CVD may yield benefits in reduced mortality and stroke as well as reducing health care costs.
Journal ArticleDOI
Secular trends in the prevalence of atrial fibrillation: The Framingham study
Philip A. Wolf,Emelia J. Benhamin,Albert J. Belanger,William B. Kannel,Daniel Levy,Ralph B. D'Agostino +5 more
TL;DR: In this paper, the authors determined the prevalence of AF from 1968 to 1989 in the Framingham Study cohort aged 65 to 84 years and evaluated the prevalence by sex and in the presence of VHD, prior MI, and CHF.
Journal ArticleDOI
Familial aggregation of atrial fibrillation in Iceland
David O. Arnar,Sverrir Thorvaldsson,Teri A. Manolio,Gudmundur Thorgeirsson,Kristleifur Kristjansson,Hakon Hakonarson,Kari Stefansson +6 more
TL;DR: AF shows strong evidence of heritability among unselected patients in Iceland, suggesting that there may be undiscovered genetic variants underlying the risk of the common form of AF.
Journal ArticleDOI
Altered Na+Currents in Atrial Fibrillation: Effects of Ranolazine on Arrhythmias and Contractility in Human Atrial Myocardium
Samuel Sossalla,Birte Kallmeyer,Stefan Wagner,Marek Mazur,Ulrike Maurer,Karl Toischer,Jan D. Schmitto,Ralf Seipelt,Friedrich A. Schöndube,Gerd Hasenfuss,Luiz Belardinelli,Lars S. Maier +11 more
TL;DR: Investigating changes in Na(+) currents in permanent (or chronic) atrial fibrillation and the effects of I(Na) inhibition using ranolazine (Ran) on arrhythmias and contractility in human atrial myocardium found antiarrhythmic effects and improved diastolic function.
Journal ArticleDOI
Atrial fibrillation and the hypercoagulable state: from basic science to clinical practice.
TL;DR: Increasing evidence points to the fulfillment of Virchow's triad in this arrhythmia, leading to a prothrombotic or hypercoagulable state in AF.