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Xiaoyan Yin
Researcher at Boston University
Publications - 64
Citations - 5947
Xiaoyan Yin is an academic researcher from Boston University. The author has contributed to research in topics: Framingham Heart Study & Atrial fibrillation. The author has an hindex of 35, co-authored 64 publications receiving 4799 citations. Previous affiliations of Xiaoyan Yin include University of Texas Health Science Center at Houston & National Institutes of Health.
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Journal ArticleDOI
50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study
Renate B. Schnabel,Xiaoyan Yin,Philimon Gona,Martin G. Larson,Alexa S. Beiser,David D. McManus,Christopher Newton-Cheh,Steven A. Lubitz,Jared W. Magnani,Patrick T. Ellinor,Patrick T. Ellinor,Sudha Seshadri,Philip A. Wolf,Ramachandran S. Vasan,Emelia J. Benjamin,Daniel Levy,Daniel Levy +16 more
TL;DR: Trends in incidence, prevalence, and risk factors for atrial fibrillation and its association with stroke and mortality after onset in 9511 participants enrolled in the Framingham Heart Study between 1958 and 2007 were investigated.
Journal ArticleDOI
Common variants at ten loci influence QT interval duration in the QTGEN Study.
Christopher Newton-Cheh,Christopher Newton-Cheh,Mark Eijgelsheim,Kenneth Rice,Paul I.W. de Bakker,Paul I.W. de Bakker,Xiaoyan Yin,Karol Estrada,Joshua C. Bis,Kristin D. Marciante,Fernando Rivadeneira,Peter A. Noseworthy,Nona Sotoodehnia,Nicholas L. Smith,Nicholas L. Smith,Jerome I. Rotter,Jan A. Kors,Jacqueline C.M. Witteman,Albert Hofman,Susan R. Heckbert,Susan R. Heckbert,Christopher J. O'Donnell,Christopher J. O'Donnell,André G. Uitterlinden,Bruce M. Psaty,Thomas Lumley,Martin G. Larson,Bruno H. Stricker +27 more
TL;DR: A meta-analysis of three genome-wide association studies in 13,685 individuals of European ancestry offers insights into myocardial repolarization and suggests candidate genes that could predispose to sudden cardiac death and drug-induced arrhythmias.
Journal ArticleDOI
Association of common variants in NPPA and NPPB with circulating natriuretic peptides and blood pressure
Christopher Newton-Cheh,Martin G. Larson,Ramachandran S. Vasan,Daniel Levy,Kenneth D. Bloch,Aarti Surti,Candace Guiducci,Sekar Kathiresan,Emelia J. Benjamin,Joachim Struck,Nils G. Morgenthaler,Andreas Bergmann,Stefan Blankenberg,Frank Kee,Peter M. Nilsson,Xiaoyan Yin,Leena Peltonen,Erkki Vartiainen,Veikko Salomaa,Joel N. Hirschhorn,Joel N. Hirschhorn,Joel N. Hirschhorn,Olle Melander,Thomas J. Wang +23 more
TL;DR: Common genetic variants at the NPPA-NPPB locus found to be associated with circulating natriuretic peptide concentrations contribute to interindividual variation in blood pressure and hypertension.
Journal ArticleDOI
Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization
Dan E. Arking,Sara L. Pulit,Sara L. Pulit,Sara L. Pulit,Lia Crotti,Pim van der Harst,Patricia B. Munroe,Tamara T. Koopmann,Nona Sotoodehnia,Elizabeth J. Rossin,Elizabeth J. Rossin,Michael Morley,Xinchen Wang,Xinchen Wang,Andrew D. Johnson,Alicia Lundby,Alicia Lundby,Daniel F. Gudbjartsson,Peter A. Noseworthy,Peter A. Noseworthy,Mark Eijgelsheim,Yuki Bradford,Kirill Tarasov,Marcus Dörr,Martina Müller-Nurasyid,Annukka M. Lahtinen,Ilja M. Nolte,Albert V. Smith,Joshua C. Bis,Aaron Isaacs,Stephen Newhouse,Daniel S. Evans,Wendy S. Post,Daryl Waggott,Leo-Pekka Lyytikäinen,Andrew A. Hicks,Lewin Eisele,David Ellinghaus,Caroline Hayward,Pau Navarro,Sheila Ulivi,Toshiko Tanaka,David J. Tester,Stéphanie Chatel,Stefan Gustafsson,Stefan Gustafsson,Meena Kumari,Richard W Morris,Åsa Torinsson Naluai,Sandosh Padmanabhan,Alexander Kluttig,Bernhard Strohmer,Andrie G. Panayiotou,María Dolores Torres,Michael Knoflach,Jaroslav A. Hubacek,Kamil Slowikowski,Soumya Raychaudhuri,Soumya Raychaudhuri,Soumya Raychaudhuri,Runjun D. Kumar,Tamara B. Harris,Lenore J. Launer,Alan R. Shuldiner,Alan R. Shuldiner,Alvaro Alonso,Joel S. Bader,Georg Ehret,Hailiang Huang,Hailiang Huang,W. H. Linda Kao,James B. Strait,Peter W. Macfarlane,Morris Brown,Mark J. Caulfield,Nilesh J. Samani,Florian Kronenberg,Johann Willeit,J. Gustav Smith,J. Gustav Smith,J. Gustav Smith,Karin Halina Greiser,Karin Halina Greiser,Henriette E. Meyer zu Schwabedissen,Karl Werdan,Massimo Carella,Leopoldo Zelante,Susan R. Heckbert,Bruce M. Psaty,Bruce M. Psaty,Jerome I. Rotter,Ivana Kolcic,Ozren Polasek,Alan F. Wright,Maura Griffin,Mark J. Daly,Mark J. Daly,David O. Arnar,Hilma Holm,Unnur Thorsteinsdottir,Joshua C. Denny,Dan M. Roden,Rebecca L. Zuvich,Valur Emilsson,Andrew S. Plump,Martin G. Larson,Martin G. Larson,Christopher J. O'Donnell,Christopher J. O'Donnell,Xiaoyan Yin,Xiaoyan Yin,Marco Bobbo,Adamo Pio D'Adamo,Annamaria Iorio,Gianfranco Sinagra,Angel Carracedo,Steven R. Cummings,Mike A. Nalls,Antti Jula,Kimmo Kontula,Annukka Marjamaa,Lasse Oikarinen,Markus Perola,Markus Perola,Markus Perola,Kimmo Porthan,Raimund Erbel,Per Hoffmann,Per Hoffmann,Karl-Heinz Jöckel,Hagen Kälsch,Markus M. Nöthen,Marcel den Hoed,Marcel den Hoed,Ruth J. F. Loos,Ruth J. F. Loos,Dag S. Thelle,Dag S. Thelle,Christian Gieger,Thomas Meitinger,Siegfried Perz,Annette Peters,Hanna Prucha,Moritz F. Sinner,Melanie Waldenberger,Rudolf A. de Boer,Lude Franke,Pieter A. van der Vleuten,Britt M. Beckmann,Eimo Martens,Abdennasser Bardai,Nynke Hofman,Arthur A.M. Wilde,Elijah R. Behr,Chrysoula Dalageorgou,John R. Giudicessi,Argelia Medeiros-Domingo,Julien Barc,Florence Kyndt,Vincent Probst,Alice Ghidoni,Roberto Insolia,Robert M. Hamilton,Stephen W. Scherer,Jeffrey Brandimarto,Kenneth B. Margulies,Christine E. Moravec,Fabiola Del Greco M,Christian Fuchsberger,Jeffrey R. O'Connell,Wai K. Lee,Graham Watt,Harry Campbell,Sarah H Wild,Nour Eddine El Mokhtari,Norbert Frey,Folkert W. Asselbergs,Folkert W. Asselbergs,Irene Mateo Leach,Gerjan Navis,Maarten P. van den Berg,Dirk J. van Veldhuisen,Manolis Kellis,Manolis Kellis,Bouwe P. Krijthe,Oscar H. Franco,Albert Hofman,Jan A. Kors,André G. Uitterlinden,Jacqueline C.M. Witteman,Lyudmyla Kedenko,Claudia Lamina,Ben A. Oostra,Gonçalo R. Abecasis,Edward G. Lakatta,Antonella Mulas,Marco Orru,David Schlessinger,Manuela Uda,Marcello Ricardo Paulista Markus,Uwe Völker,Harold Snieder,Tim D. Spector,Johan Ärnlöv,Johan Ärnlöv,Lars Lind,Johan Sundström,Ann-Christine Syvänen,Mika Kivimäki,Mika Kähönen,Nina Mononen,Olli T. Raitakari,Jorma S. A. Viikari,Vera Adamkova,Stefan Kiechl,Maria Brion,Andrew N. Nicolaides,Bernhard Paulweber,Johannes Haerting,Anna F. Dominiczak,Fredrik Nyberg,Fredrik Nyberg,Peter H. Whincup,Aroon D. Hingorani,Jean-Jacques Schott,Connie R. Bezzina,Erik Ingelsson,Erik Ingelsson,Luigi Ferrucci,Paolo Gasparini,James F. Wilson,Igor Rudan,Andre Franke,Thomas W. Mühleisen,Peter P. Pramstaller,Terho Lehtimäki,Andrew D. Paterson,Afshin Parsa,Yongmei Liu,Cornelia M. van Duijn,David S. Siscovick,Vilmundur Gudnason,Yalda Jamshidi,Veikko Salomaa,Stephan B. Felix,Serena Sanna,Marylyn D. Ritchie,Bruno H. Stricker,Kari Stefansson,Laurie A. Boyer,Thomas P. Cappola,Jesper V. Olsen,Kasper Lage,Peter J. Schwartz,Stefan Kääb,Aravinda Chakravarti,Michael J. Ackerman,Arne Pfeufer,Paul I.W. de Bakker,Christopher Newton-Cheh,Christopher Newton-Cheh +260 more
TL;DR: In this paper, the authors identified 35 common variant loci associated with QT interval that collectively explain ∼8-10% of QT-interval variation and highlight the importance of calcium regulation in myocardial repolarization.
Journal ArticleDOI
Association Between Familial Atrial Fibrillation and Risk of New-Onset Atrial Fibrillation
Steven A. Lubitz,Xiaoyan Yin,João D. Fontes,Jared W. Magnani,Michiel Rienstra,Manju Pai,Mark L. Villalon,Ramachandran S. Vasan,Michael J. Pencina,Daniel Levy,Martin G. Larson,Patrick T. Ellinor,Emelia J. Benjamin +12 more
TL;DR: In this cohort, familial AF was associated with an increased risk of AF that was not attenuated by adjustment for AF risk factors including genetic variants and categoryless net reclassification improvement was improved.