Journal ArticleDOI
A biodegradable hydrogel system containing curcumin encapsulated in micelles for cutaneous wound healing.
TLDR
Biodegradable Cur-M-H composite might have great application for wound healing because of its well tissue adhesiveness and ability to release curcumin in an extended period.About:
This article is published in Biomaterials.The article was published on 2013-09-01. It has received 420 citations till now. The article focuses on the topics: Wound healing.read more
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Antibacterial anti-oxidant electroactive injectable hydrogel as self-healing wound dressing with hemostasis and adhesiveness for cutaneous wound healing
TL;DR: The antibacterial electroactive injectable hydrogel dressing prolonged the lifespan of dressing relying on self-healing ability and significantly promoted the in vivo wound healing process attributed to its multifunctional properties, meaning that they are excellent candidates for full-thickness skin wound healing.
Journal ArticleDOI
Antibacterial adhesive injectable hydrogels with rapid self-healing, extensibility and compressibility as wound dressing for joints skin wound healing.
TL;DR: In vivo experiments indicated that curcumin loaded hydrogels significantly accelerated wound healing rate with higher granulation tissue thickness and collagen disposition and upregulated vascular endothelial growth factor (VEGF) in a full-thickness skin defect model.
Journal ArticleDOI
Curcumin nanoformulations : A review of pharmaceutical properties and preclinical studies and clinical data related to cancer treatment
TL;DR: Recent works on the design and development of nano-sized delivery systems for curcumin, including liposomes, polymeric nanoparticles and micelles, conjugates, peptide carriers, cyclodextrins, solid dispersions, lipid nanoparticlesand emulsions are summarized.
Journal ArticleDOI
Functional Hydrogels as Wound Dressing to Enhance Wound Healing.
TL;DR: In this paper, a comprehensive review of the functional hydrogel as a wound dressing is presented, which summarizes the skin wound healing process and relates evaluation parameters and then reviews the advanced functions of hydrogels such as antimicrobial property, adhesion and hemostasis, anti-inflammatory and anti-oxidation, substance delivery, self-healing, stimulus response, conductivity, and the recently emerged wound monitoring feature.
Journal ArticleDOI
A Novel Wound Dressing Based on Ag/Graphene Polymer Hydrogel: Effectively Kill Bacteria and Accelerate Wound Healing
Zengjie Fan,Bin Liu,Jinqing Wang,Songying Zhang,Qianqian Lin,Peiwei Gong,Limin Ma,Shengrong Yang +7 more
TL;DR: In this article, a series of hydrogels are prepared by crosslinking of Ag/graphene composites with acrylic acid and N,N'-methylene bisacrylamide at different mass ratios.
References
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Journal ArticleDOI
Bioavailability of curcumin: problems and promises.
TL;DR: Enhanced bioavailability of curcumin in the near future is likely to bring this promising natural product to the forefront of therapeutic agents for treatment of human disease.
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Curcumin as “Curecumin”: From kitchen to clinic
TL;DR: Curcumin, a spice once relegated to the kitchen shelf, has moved into the clinic and may prove to be "Curecumin", a therapeutic agent in wound healing, diabetes, Alzheimer disease, Parkinson disease, cardiovascular disease, pulmonary disease, and arthritis.
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Multiple biological activities of curcumin: a short review.
TL;DR: This review summarizes the most interesting in vitro and in vivo studies on the biological effects of curcumin, the constituent of turmeric, which has been widely studied for its anti-inflammatory, anti-angiogenic,Anti-oxidant, wound healing and anti-cancer effects.
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The cellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survival
TL;DR: The results suggest that ERK and JNK/SAPK act in opposition to influence cell survival in response to oxidative stress, whereas neither p38 nor NF-kappaB affects the outcome.
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Liposome-encapsulated curcumin: in vitro and in vivo effects on proliferation, apoptosis, signaling, and angiogenesis.
TL;DR: Curcumin (diferuloylmethane) is a phytochemical with potent NF‐κB‐inhibitory activity, which is pharmacologically safe, but its bioavailability is poor after oral administration.