A numerical study of microparticle acoustophoresis driven by acoustic radiation forces and streaming-induced drag forces
TLDR
A numerical study of the transient acoustophoretic motion of microparticles suspended in a liquid-filled microchannel and driven by the acoustic forces arising from an imposed standing ultrasound wave shows the transition in the acoustrophoretic particle motion from being dominated by streaming-induced drag tobeing dominated by radiation forces as a function of particle size, channel geometry, and material properties.Abstract:
We present a numerical study of the transient acoustophoretic motion of microparticles suspended in a liquid-filled microchannel and driven by the acoustic forces arising from an imposed standing ultrasound wave: the acoustic radiation force from the scattering of sound waves on the particles and the Stokes drag force from the induced acoustic streaming flow. These forces are calculated numerically in two steps. First, the thermoacoustic equations are solved to first order in the imposed ultrasound field taking into account the micrometer-thin but crucial thermoviscous boundary layer near the rigid walls. Second, the products of the resulting first-order fields are used as source terms in the time-averaged second-order equations, from which the net acoustic forces acting on the particles are determined. The resulting acoustophoretic particle velocities are quantified for experimentally relevant parameters using a numerical particle-tracking scheme. The model shows the transition in the acoustophoretic particle motion from being dominated by streaming-induced drag to being dominated by radiation forces as a function of particle size, channel geometry, and material properties.read more
Citations
More filters
Journal ArticleDOI
Three-dimensional manipulation of single cells using surface acoustic waves
Feng Guo,Zhangming Mao,Yuchao Chen,Zhiwei Xie,James P. Lata,Peng Li,Liqiang Ren,Jiayang Liu,Jian Yang,Ming Dao,Subra Suresh,Tony Jun Huang +11 more
TL;DR: 3D acoustic tweezers are presented, which can trap and manipulate single cells and particles along three mutually orthogonal axes of motion by recourse to surface acoustic waves, and are shown to offer better performance over prior cell manipulation techniques in terms of both accurate and precise motion.
Journal ArticleDOI
Two-dimensional single-cell patterning with one cell per well driven by surface acoustic waves
David J. Collins,Belinda Joan Morahan,Jose F. Garcia-Bustos,Christian Doerig,Magdalena Plebanski,Adrian Neild +5 more
TL;DR: A new method for the patterning of multiple spatially separated single particles and cells using high-frequency acoustic fields with one cell per acoustic well is introduced, made possible by a hitherto unexplored regime where the acoustic wavelength is on the same order as the cell dimensions.
Journal ArticleDOI
Acoustofluidic separation of cells and particles.
TL;DR: Focusing on product development and technological improvements will enable acoustofluidic separation to find real-world applications, the researchers conclude.
Journal ArticleDOI
Correction: Corrigendum: A comprehensive strategy for the analysis of acoustic compressibility and optical deformability on single cells
Tie Yang,Francesca Bragheri,Giovanni Nava,Ilaria Chiodi,Chiara Mondello,Roberto Osellame,Kirstine Berg-Sørensen,Ilaria Cristiani,Paolo Minzioni +8 more
TL;DR: This paper presents a probabilistic procedure for estimating acoustic compressibility in the presence of low-frequency noise, and shows good results for both low and high-frequency compressibility experiments.
Journal ArticleDOI
Numerical study of acoustophoretic motion of particles in a PDMS microchannel driven by surface acoustic waves
Nitesh Nama,Rune Barnkob,Zhangming Mao,Christian J. Kähler,Francesco Costanzo,Tony Jun Huang +5 more
TL;DR: A numerical study of the acoustophoretic motion of particles suspended in a liquid-filled PDMS microchannel on a lithium niobate substrate acoustically driven by surface acoustic waves using a perturbation approach and demonstrates the capability to tune the position of the vertical pressure node along the channel width by tuning the phase difference between two incoming surfaceoustic waves.
References
More filters
Book
Theory of elasticity
TL;DR: The theory of the slipline field is used in this article to solve the problem of stable and non-stressed problems in plane strains in a plane-strain scenario.
Book
Theory of elasticity
TL;DR: The equilibrium of rods and plates Elastic waves Dislocations Thermal conduction and viscosity in solids Mechanics of liquid crystals Index as discussed by the authors The equilibrium of rod and plate elastic waves Elastic waves
Book
Particle Image Velocimetry: A Practical Guide
TL;DR: In this paper, the authors present a practical guide for the planning, performance and understanding of experiments employing the PIV technique, which is primarily intended for engineers, scientists and students, who already have some basic knowledge of fluid mechanics and nonintrusive optical measurement techniques.
Book ChapterDOI
Particle Image Velocimetry
TL;DR: In this paper, the authors use hot-wire (HW) or laser velocimetry (LV) to estimate the velocity, vorticity, and pressure fields of wake flows.
Related Papers (5)
Forces acting on a small particle in an acoustical field in a viscous fluid
Mikkel Settnes,Henrik Bruus +1 more
Microscale acoustofluidics: Microfluidics driven via acoustics and ultrasonics
James Friend,Leslie Y. Yeo +1 more