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Journal ArticleDOI

A review of botanical characteristics, phytochemistry, clinical relevance in efficacy and safety of Lycium barbarum fruit (Goji)

TLDR
A review of chemical constituents and efficacies with safety of L. barbarum can be found in this article, where a new direction for research and current regulatory situation of the chemical constituents are discussed.
About
This article is published in Food Research International.The article was published on 2011-08-01. It has received 442 citations till now. The article focuses on the topics: Goji berry.

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Citations
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Journal ArticleDOI

Biological activities and potential health benefit effects of polysaccharides isolated from Lycium barbarum L.

TL;DR: The purpose of the present review is to summarize previous and current references regarding biological activities as well as potential health benefits of L. barbarum polysaccharides.
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Characterization and hypoglycemic effect of a polysaccharide extracted from the fruit of Lycium barbarum L.

TL;DR: In vitro and in vivo hypoglycemic experiments showed that LBP-s-1 had significanthypoglycemic effects and insulin-sensitizing activity through increasing glucose metabolism and insulin secretion and promoting pancreatic β cell proliferation.
Journal ArticleDOI

Goji berry fruit (Lycium spp.): antioxidant compound fingerprint and bioactivity evaluation

TL;DR: Goji berry was identified as a rich source of antioxidant compounds, with health-promoting properties comparable with other common fruit species, and may be useful to better understand the nutraceutical traits of this species recently considered as functional food.
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An evidence-based update on the pharmacological activities and possible molecular targets of Lycium barbarum polysaccharides.

TL;DR: There is increasing evidence from preclinical and clinical studies supporting the therapeutic and health-promoting effects of LBPs, but further mechanistic and clinical Studies are warranted to establish the dose–response relationships and safety profiles of LBP.
Journal ArticleDOI

Lycium barbarum polysaccharides: Extraction, purification, structural characterisation and evidence about hypoglycaemic and hypolipidaemic effects. A review.

TL;DR: The evidence suggests that these purified components of the Goji berry may be potentially useful as adjuvants in the treatment of diabetes and its correlated illnesses.
References
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Journal ArticleDOI

Effect of the Lycium barbarum polysaccharides administration on blood lipid metabolism and oxidative stress of mice fed high-fat diet in vivo

TL;DR: This study revealed that HF diet induced oxidative stress and provided novel evidence regarding the link between high dietary fat and increased risk of degenerative diseases and showed a noticeable inhibition against lipid oxidation induced by free radicals caused by HF diet intake.
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Antioxidative activity of polysaccharide fractions isolated from Lycium barbarum Linnaeus.

TL;DR: With the exception of CE and DDP, most polysaccharides were effective in scavenging DPPH and ABTS(.)+ free radicals, superoxide anion and hydroxyl radical at 1000 microg/mL.
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Effect of lycium barbarum polysaccharide on human hepatoma QGY7703 cells: Inhibition of proliferation and induction of apoptosis

TL;DR: The study suggests that the induction of cell cycle arrest and the increase of intracellular calcium in apoptotic system may participate in the antiproliferative activity of LBP in QGY7703 cells.
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Simultaneous determination of phenolic acids and flavonoids in Lycium barbarum Linnaeus by HPLC-DAD-ESI-MS.

TL;DR: A high-performance liquid chromatography-diode array detection-mass spectrometry method with electrospray ionization mode (HPLC-DAD-ESI-MS) was developed for simultaneous determination of phenolic acids and flavonoids in fruits of Lycium barbarum Linnaeus, a widely used traditional Chinese herb possessing vital biological activity.
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Quantification of zeaxanthin dipalmitate and total carotenoids in Lycium fruits (Fructus Lycii).

TL;DR: This study is the first systematic quantification of the carotenoids in the fruits of different Lycium species, demonstrating that these methods are reliable and facile techniques for rapid analysis of carotanoids for crude drug and plant-derived food supplements.
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